GB662591A - Manufacture of new basic ethers - Google Patents

Manufacture of new basic ethers

Info

Publication number
GB662591A
GB662591A GB21295/49A GB2129549A GB662591A GB 662591 A GB662591 A GB 662591A GB 21295/49 A GB21295/49 A GB 21295/49A GB 2129549 A GB2129549 A GB 2129549A GB 662591 A GB662591 A GB 662591A
Authority
GB
United Kingdom
Prior art keywords
diethylamino
cyclohexane
manufacture
basic ethers
substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21295/49A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spofa Spojene Farmaceuticke Zavody
Original Assignee
Spofa Spojene Farmaceuticke Zavody
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Spojene Farmaceuticke Zavody filed Critical Spofa Spojene Farmaceuticke Zavody
Publication of GB662591A publication Critical patent/GB662591A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Basic ethers are obtained by condensing metal derivatives of substances of the formula R.O.M, where R is aryl or aralkyl and M is an atom of monovalent metal, with substances of the formula <FORM:0662591/IV (b)/1> where Hal is chlorine or bromine and Y is an alkyl radical or the whole N(Y)2-group may be the residue of a secondary heterocyclic amine. The condensation may be effected at an elevated temperature in water - immiscible solvents. Detailed examples are given of the preparation of 1 - phenoxy - 2 - diethylamino - cyclohexane, 1 - thymoxy - 2 - diethylamino - cyclohexane, 1 - benzyloxy - 2 - diethylamino - cyclohexane, 1 - phenylcyclohexyloxy - 2 - diethylamino - cyclohexane and 1-benzhydryloxy-2-diethylamino-cyclohexane.
GB21295/49A 1948-08-19 1949-08-16 Manufacture of new basic ethers Expired GB662591A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS662591X 1948-08-19

Publications (1)

Publication Number Publication Date
GB662591A true GB662591A (en) 1951-12-05

Family

ID=5454491

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21295/49A Expired GB662591A (en) 1948-08-19 1949-08-16 Manufacture of new basic ethers

Country Status (1)

Country Link
GB (1) GB662591A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3156725A (en) * 1962-04-18 1964-11-10 Smith Kline French Lab Substituted 2-phenoxy and phenylthio-cyclopropylamines
US4008329A (en) * 1974-08-05 1977-02-15 Societe Anonyme Dite: Centre Europen De Recherches Mauvernay (C.E.R.M.) Substituted cyclohexanes, pharmaceutical compositions containing them and method of treatment involving their use
US4956388A (en) * 1986-12-22 1990-09-11 Eli Lilly And Company 3-aryloxy-3-substituted propanamines

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3156725A (en) * 1962-04-18 1964-11-10 Smith Kline French Lab Substituted 2-phenoxy and phenylthio-cyclopropylamines
US4008329A (en) * 1974-08-05 1977-02-15 Societe Anonyme Dite: Centre Europen De Recherches Mauvernay (C.E.R.M.) Substituted cyclohexanes, pharmaceutical compositions containing them and method of treatment involving their use
US4956388A (en) * 1986-12-22 1990-09-11 Eli Lilly And Company 3-aryloxy-3-substituted propanamines

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