GB446703A - Process for the manufacture of phenyl mercury nitrates - Google Patents
Process for the manufacture of phenyl mercury nitratesInfo
- Publication number
- GB446703A GB446703A GB873435A GB873435A GB446703A GB 446703 A GB446703 A GB 446703A GB 873435 A GB873435 A GB 873435A GB 873435 A GB873435 A GB 873435A GB 446703 A GB446703 A GB 446703A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nitrate
- nitric acid
- solution
- basic
- dilute
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- PDTFCHSETJBPTR-UHFFFAOYSA-N phenylmercuric nitrate Chemical class [O-][N+](=O)O[Hg]C1=CC=CC=C1 PDTFCHSETJBPTR-UHFFFAOYSA-N 0.000 title 1
- 229910002651 NO3 Inorganic materials 0.000 abstract 10
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 9
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract 8
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 abstract 8
- 229910017604 nitric acid Inorganic materials 0.000 abstract 8
- 230000007935 neutral effect Effects 0.000 abstract 4
- 239000000243 solution Substances 0.000 abstract 4
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 abstract 3
- 229910004679 ONO2 Inorganic materials 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 238000001816 cooling Methods 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 239000000284 extract Substances 0.000 abstract 2
- 125000001893 nitrooxy group Chemical group [O-][N+](=O)O* 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- MSYUMXXVCSLXMR-UHFFFAOYSA-N phenylmercury;hydrate Chemical compound O.[Hg]C1=CC=CC=C1 MSYUMXXVCSLXMR-UHFFFAOYSA-N 0.000 abstract 2
- 239000002244 precipitate Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- HIXDQWDOVZUNNA-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxychromen-4-one Chemical compound C=1C(OC)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(OC)C(OC)=C1 HIXDQWDOVZUNNA-UHFFFAOYSA-N 0.000 abstract 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 230000008020 evaporation Effects 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000000417 fungicide Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 150000002823 nitrates Chemical class 0.000 abstract 1
- XEBWQGVWTUSTLN-UHFFFAOYSA-M phenylmercury acetate Chemical compound CC(=O)O[Hg]C1=CC=CC=C1 XEBWQGVWTUSTLN-UHFFFAOYSA-M 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 235000010344 sodium nitrate Nutrition 0.000 abstract 1
- 239000004317 sodium nitrate Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
- C07F3/12—Aromatic substances containing mercury
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
From the nitrates of hydroxy-mercurybenzene obtained in known way, a neutral nitrate C6H5.Hg.ONO2 is isolated by extraction with a water-immiscible organic solvent, such as ethyl acetate, and ether, from an aqueous solution or suspension of the crude preparation containing free nitric acid. By dissolving the crude preparation in hot dilute aqueous nitric acid and cooling, a precipitate of the basic nitrate C6H5.Hg.ONO2+C6H5.Hg.OH is obtained. The neutral nitrate may be converted into the basic nitrate by dissolving it in water or in dilute aqueous nitric acid and allowing the solution to crystallize, whilst the basic nitrate may be transformed into the neutral nitrate by suspending it in dilute aqueous nitric acid and extracting with a water-immiscible organic solvent. The products are useful in therapy and as fungicides, insecticides and disinfectants. According to the examples: (1) phenylmercury acetate (see Specification 325,846, [Class 2 (iii)]) is treated in cold aqueous solution with sodium nitrate, the precipitate taken up by heating the solution after addition of a little dilute nitric acid, and the basic nitrate p allowed to crystallize out; (2) the basic nitrate of (1) is suspended in dilute nitric acid and agitated with ethyl acetate, whereby the solid is dissolved; the solution is then extracted twice with ethyl acetate and water removed from the extracts by shaking with saturated sodium nitrate solution; on evaporation of the extracts in vacuo, and also on addition of benzine, the neutral nitrate separates out; (3) phenylmercury hydroxide or carbonate is dissolved in the minimum quantity of boiling dilute nitric acid, from which the basic nitrate separates on cooling; (4) phenylmercury hydroxide is suspended in dilute nitric acid and treated according to (2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB873435A GB446703A (en) | 1935-03-20 | 1935-03-20 | Process for the manufacture of phenyl mercury nitrates |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB873435A GB446703A (en) | 1935-03-20 | 1935-03-20 | Process for the manufacture of phenyl mercury nitrates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB446703A true GB446703A (en) | 1936-05-05 |
Family
ID=9858229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB873435A Expired GB446703A (en) | 1935-03-20 | 1935-03-20 | Process for the manufacture of phenyl mercury nitrates |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB446703A (en) |
-
1935
- 1935-03-20 GB GB873435A patent/GB446703A/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB446703A (en) | Process for the manufacture of phenyl mercury nitrates | |
| US1924073A (en) | Stable ammonium salt of primula saponine | |
| US1987743A (en) | Compounds of primula saponine | |
| GB337797A (en) | A specific for cancer | |
| GB989496A (en) | Sultone and method for the preparation thereof | |
| GB1033080A (en) | Manufacture of relatively pure para-hydroxymethyl-benzoic acid | |
| AT263814B (en) | Process for the production of a new poly-γ-propylsulfonic acid ether of inulin | |
| Lauer et al. | Ethers of p-Hydroxybenzoic Acid as Derivatives for the Identification of Alkyl Halides | |
| GB1072238A (en) | Process for the preparation of pivalolactone | |
| US2333050A (en) | Separating hematoxylin from logwood extract | |
| SU105849A1 (en) | The method of producing tetraethylthiopirophosphate | |
| GB1049229A (en) | Process for the preparation of aliphatic ªÏ-cyanocarboxylic acids | |
| SU143963A1 (en) | Method for isolating crystalline sodium salt of 6-aminopenicillanic acid from culture fluid obtained by deep fermentation of the microorganism Pemcillium chrysogenum | |
| GB469430A (en) | Process of producing and refining organ extracts | |
| GB482125A (en) | Process for the preparation of new hormones from the male sex apparatus and the new hormones obtained by such process | |
| GB866365A (en) | Trimethylolethane | |
| GB913059A (en) | New oestrogenic substance | |
| GB807590A (en) | Method for the preparation of organic salts of the rare earths, with good solubility in water, which possess an inhibitory action on blood coagulation | |
| GB953830A (en) | A process for the resolution of racemic homocysteic acids | |
| Rao | A note on the methylation of quercetagetin | |
| GB497746A (en) | Preparation of a complex derivative of gold | |
| GB720166A (en) | Method of preparing the tri-p-aminosalicylate of dihydrostreptomycin | |
| GB642369A (en) | Improvements in or relating to process for preparing pure crystalline salts of penicillin, and the pure crystalline salts of penicillin resulting therefrom | |
| GB357926A (en) | Manufacture of a new crystallized product from digitalis | |
| GB699575A (en) | Method of preparing 1-p-nitrophenyl-2-acylamino-1,3-propanediols |