GB953830A - A process for the resolution of racemic homocysteic acids - Google Patents
A process for the resolution of racemic homocysteic acidsInfo
- Publication number
- GB953830A GB953830A GB42098/62A GB4209862A GB953830A GB 953830 A GB953830 A GB 953830A GB 42098/62 A GB42098/62 A GB 42098/62A GB 4209862 A GB4209862 A GB 4209862A GB 953830 A GB953830 A GB 953830A
- Authority
- GB
- United Kingdom
- Prior art keywords
- solution
- optically active
- isomer
- racemic
- racemate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/34—Preparation of optical isomers by separation of optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
DL-Homocysteic acid or the monoammonium last thereof is optically resolved by making and maintaining a supersaturated aqueous solution of the racemate or of the racemate and a small amount of optically active isomer, crystallizing an optically active isomer from the solution in the presence of crystals of optically active isomer and separating the crystals from the solution. After the crystals have been separated from the solution, more racemate or the other isomer is added thereto and this other isomer is then crystallized out and separated from the solution. Pure optically active homocysteic acid or the monoammonium salt thereof is obtained by dissolving optically active homocysteic acid which is contaminated with racemic acid in sufficient water, aqueous mineral acid, aqueous alkali or mixed solvent of water and a water-soluble organic solvent to dissolve the racemic component completely to form a solution which is at least substantially saturated with respect to the racemic component, and separating the optically active component remaining as a solid phase from the liquid phase.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3972261 | 1961-11-08 | ||
JP4112961 | 1961-11-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB953830A true GB953830A (en) | 1964-04-02 |
Family
ID=26379091
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB42098/62A Expired GB953830A (en) | 1961-11-08 | 1962-11-07 | A process for the resolution of racemic homocysteic acids |
Country Status (2)
Country | Link |
---|---|
CH (1) | CH401082A (en) |
GB (1) | GB953830A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0090866A1 (en) * | 1982-04-02 | 1983-10-12 | Showa Denko Kabushiki Kaisha | Optical resolution process for DL-cysteine |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3211127C1 (en) * | 1982-03-26 | 1983-08-11 | Degussa Ag, 6000 Frankfurt | Process for the production of S- (carboxymethyl) - (R) -cysteine and S- (carboxymethyl) - (S) -cysteine |
-
1962
- 1962-11-07 GB GB42098/62A patent/GB953830A/en not_active Expired
- 1962-11-07 CH CH1299862A patent/CH401082A/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0090866A1 (en) * | 1982-04-02 | 1983-10-12 | Showa Denko Kabushiki Kaisha | Optical resolution process for DL-cysteine |
Also Published As
Publication number | Publication date |
---|---|
CH401082A (en) | 1965-10-31 |
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