GB334898A - Process for extracting and separating the active substances from the posterior lobe of the hypophysis - Google Patents

Process for extracting and separating the active substances from the posterior lobe of the hypophysis

Info

Publication number
GB334898A
GB334898A GB1729629A GB1729629A GB334898A GB 334898 A GB334898 A GB 334898A GB 1729629 A GB1729629 A GB 1729629A GB 1729629 A GB1729629 A GB 1729629A GB 334898 A GB334898 A GB 334898A
Authority
GB
United Kingdom
Prior art keywords
ether
precipitated
act
alcohol
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1729629A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IG Farbenindustrie AG
Original Assignee
IG Farbenindustrie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IG Farbenindustrie AG filed Critical IG Farbenindustrie AG
Priority to GB1729629A priority Critical patent/GB334898A/en
Publication of GB334898A publication Critical patent/GB334898A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

334,898. Groves, W'. W., (I. G. Farbenindustrie Akt.-Ges.). June 11, 1929. Hormones. - The hormones or active substances present in the, posterior lobe of the hypoplysis are extracted and separated into those which act on the uterus and those which increase the blood pressure. The fresh or dried gland is extracted with methyl or other alcohol containing hydrochloric sulphuric or other inorganic acid. The extract is precipitated either by neutralizing the acid by means of methyl alcohol containing ammonia or by addition of ether or other organic precipitant. The precipitate is dissolved in acidified alcohol and the solution is precipitated fractionally with acetone and ether, the first fractions containing more of the substances which act on the blood pressure- The filtrates containing the substances which act on the uterus are concentrated while feebly acid, shaken with water to form two layers, and the hormone obtained by distilling the alcohol from the aqueous layer and precipitating with petroleum ether. Alternatively the original extract may be precipitated first with acetone and then with ether.
GB1729629A 1929-06-11 1929-06-11 Process for extracting and separating the active substances from the posterior lobe of the hypophysis Expired GB334898A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1729629A GB334898A (en) 1929-06-11 1929-06-11 Process for extracting and separating the active substances from the posterior lobe of the hypophysis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1729629A GB334898A (en) 1929-06-11 1929-06-11 Process for extracting and separating the active substances from the posterior lobe of the hypophysis

Publications (1)

Publication Number Publication Date
GB334898A true GB334898A (en) 1930-09-11

Family

ID=10092685

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1729629A Expired GB334898A (en) 1929-06-11 1929-06-11 Process for extracting and separating the active substances from the posterior lobe of the hypophysis

Country Status (1)

Country Link
GB (1) GB334898A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2910404A (en) * 1953-03-26 1959-10-27 Armour & Co Preparation of oxytocin and acth

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2910404A (en) * 1953-03-26 1959-10-27 Armour & Co Preparation of oxytocin and acth

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