GB2552405B - A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders - Google Patents
A combination pharmaceutical composition and methods of treating diabetes and metabolic disordersInfo
- Publication number
- GB2552405B GB2552405B GB1707872.6A GB201707872A GB2552405B GB 2552405 B GB2552405 B GB 2552405B GB 201707872 A GB201707872 A GB 201707872A GB 2552405 B GB2552405 B GB 2552405B
- Authority
- GB
- United Kingdom
- Prior art keywords
- methods
- pharmaceutical composition
- metabolic disorders
- treating diabetes
- combination pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2010130348/15A RU2531048C2 (ru) | 2010-07-21 | 2010-07-21 | Лекарственное средство для уменьшения резистентности к инсулину и лечения сахарного диабета и способ повышения эффективности лечения сахарного диабета инсулином и/или гипогликемическими препаратами |
| RU2011127051/15A RU2509572C2 (ru) | 2011-07-01 | 2011-07-01 | Лекарственное средство для уменьшения резистентности к инсулину и для лечения сахарного диабета, способ уменьшения резистентности к инсулину, способ лечения сахарного диабета и способ лечения сахарного диабета инсулином и/или гипогликемическими препаратами |
| GB1302924.4A GB2496799B (en) | 2010-07-21 | 2011-07-15 | A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB201707872D0 GB201707872D0 (en) | 2017-06-28 |
| GB2552405A GB2552405A (en) | 2018-01-24 |
| GB2552405B true GB2552405B (en) | 2018-05-30 |
Family
ID=44899155
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1707872.6A Expired - Fee Related GB2552405B (en) | 2010-07-21 | 2011-07-15 | A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders |
| GB1302924.4A Expired - Fee Related GB2496799B (en) | 2010-07-21 | 2011-07-15 | A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1302924.4A Expired - Fee Related GB2496799B (en) | 2010-07-21 | 2011-07-15 | A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders |
Country Status (30)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2181297C2 (ru) | 2000-06-20 | 2002-04-20 | Эпштейн Олег Ильич | Способ лечения патологического синдрома и лекарственное средство |
| UA76638C2 (en) | 2002-08-02 | 2006-08-15 | Oleh Illich Epshtein | Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon |
| RU2309732C1 (ru) * | 2006-03-13 | 2007-11-10 | Олег Ильич Эпштейн | Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата |
| WO2007149010A1 (en) * | 2006-06-06 | 2007-12-27 | Oleg Iliich Epshtein | Medicinal agent for treating fatness, diabetes, and diseases associated with impaired glucose tolerance |
| WO2012007845A2 (en) * | 2010-07-15 | 2012-01-19 | Oleg Iliich Epshtein | A method of increasing the effect of an activated-potentiated form of an antibody |
| US8637034B2 (en) | 2010-07-15 | 2014-01-28 | Oleg I. Epshtein | Pharmaceutical compositions comprising activated-potentiated antibodies to interferon-gamma and S100 protein |
| ES2542042R1 (es) | 2010-07-15 | 2015-10-06 | Oleg Iliich Epshtein | Composiciones farmacéuticas y uso para preparar un medicamento destinado al tratamiento de la obesidad, los trastornos metabólicos relacionados y la adicción a sustancias psicoactivas |
| KR20130102542A (ko) * | 2010-07-21 | 2013-09-17 | 올레그 일리치 엡쉬테인 | 현기증, 동요병 및 증식형-혈관 이긴장증 치료용 제약학적 복합 조성물 및 치료 방법들 |
| ES2425315R1 (es) * | 2010-07-21 | 2014-09-08 | Oleg Iliich Epshtein | Composición farmacéutica y su uso para preparar un medicamento destinado al tratamiento sintomático de una enfermedad o afección respiratoria |
| CN103119061A (zh) | 2010-07-21 | 2013-05-22 | 奥列格·伊里奇·爱泼斯坦 | 治疗注意力不足过动症的方法 |
| JP2013537532A (ja) * | 2010-08-06 | 2013-10-03 | イリイチ・エプシテイン オレグ | 感染性疾患を治療及び予防する組み合わせ医薬組成物及び方法 |
| TWI588153B (zh) * | 2012-05-18 | 2017-06-21 | 中國醫藥大學 | 多胜肽、編碼該多胜肽之核酸分子、以及該多胜肽之應用 |
| RU2013111962A (ru) | 2013-03-18 | 2014-09-27 | Олег Ильич Эпштейн | Способ определения выраженности модифицирующей активности, ассоциированной с носителем |
| RU2013111961A (ru) | 2013-03-18 | 2014-09-27 | Олег Ильич Эпштейн | Способ определения выраженности модифицирующей активности, ассоциированной с носителем |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1547612A1 (en) * | 2002-08-02 | 2005-06-29 | Oleg Iliich Epshtein | Medicinal agent and method for curing erectile dysfunction |
| EP2036574A1 (en) * | 2006-06-06 | 2009-03-18 | Oleg Iliich Epshtein | Medicinal agent for treating fatness, diabetes, and diseases associated with impaired glucose tolerance |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4311897A (en) | 1979-08-28 | 1982-01-19 | Union Carbide Corporation | Plasma arc torch and nozzle assembly |
| US5811437A (en) * | 1996-05-21 | 1998-09-22 | Eli Lilly And Company | Methods of increasing nitric oxide synthesis |
| US6150500A (en) * | 1996-07-12 | 2000-11-21 | Salerno; John C. | Activators of endothelial nitric oxide synthase |
| WO1999026657A1 (en) * | 1997-11-25 | 1999-06-03 | Musc Foundation For Research Development | Inhibitors of nitric oxide synthase |
| US6933272B1 (en) * | 1998-09-22 | 2005-08-23 | Erik Helmerhorst | Use of non-peptidyl compounds for the treatment of insulin related ailments |
| RU2181297C2 (ru) * | 2000-06-20 | 2002-04-20 | Эпштейн Олег Ильич | Способ лечения патологического синдрома и лекарственное средство |
| UA76638C2 (en) | 2002-08-02 | 2006-08-15 | Oleh Illich Epshtein | Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon |
| UA76641C2 (uk) | 2002-08-02 | 2006-08-15 | Олєг Ільіч Епштєйн | Гомеопатичний лікарський засіб та спосіб лікування захворювань передміхурової залози |
| AU2003262804A1 (en) * | 2002-08-22 | 2004-03-11 | Nutrition 21, Inc. | Arginine silicate inositol complex and use thereof |
| CN101107003B (zh) | 2003-03-14 | 2012-08-08 | 营养学研究有限公司 | 用于治疗疼痛和/或炎症的顺势疗法的配剂 |
| MXPA06008180A (es) * | 2004-01-20 | 2006-08-31 | Astellas Pharma Inc | Metodo para tratar disfuncion erectil. |
| RU2438707C2 (ru) * | 2006-06-06 | 2012-01-10 | Олег Ильич Эпштейн | Лекарственное средство для перорального лечения сахарного диабета и других заболеваний, сопровождающихся нарушением толерантности к глюкозе, и способ получения твердой лекарственной формы для пероральной терапии сахарного диабета и других заболеваний, сопровождающихся нарушением толерантности к глюкозе |
| GB0812019D0 (en) * | 2008-07-02 | 2008-08-06 | Asterion Ltd | Insulin |
| WO2012007845A2 (en) * | 2010-07-15 | 2012-01-19 | Oleg Iliich Epshtein | A method of increasing the effect of an activated-potentiated form of an antibody |
| US8637034B2 (en) * | 2010-07-15 | 2014-01-28 | Oleg I. Epshtein | Pharmaceutical compositions comprising activated-potentiated antibodies to interferon-gamma and S100 protein |
| ES2542042R1 (es) * | 2010-07-15 | 2015-10-06 | Oleg Iliich Epshtein | Composiciones farmacéuticas y uso para preparar un medicamento destinado al tratamiento de la obesidad, los trastornos metabólicos relacionados y la adicción a sustancias psicoactivas |
| KR20130102542A (ko) * | 2010-07-21 | 2013-09-17 | 올레그 일리치 엡쉬테인 | 현기증, 동요병 및 증식형-혈관 이긴장증 치료용 제약학적 복합 조성물 및 치료 방법들 |
| ES2425315R1 (es) * | 2010-07-21 | 2014-09-08 | Oleg Iliich Epshtein | Composición farmacéutica y su uso para preparar un medicamento destinado al tratamiento sintomático de una enfermedad o afección respiratoria |
-
2011
- 2011-07-15 EP EP11773314.7A patent/EP2595658A2/en not_active Ceased
- 2011-07-15 SG SG2013004817A patent/SG187578A1/en unknown
- 2011-07-15 IT IT000627A patent/ITTO20110627A1/it unknown
- 2011-07-15 JP JP2013520235A patent/JP2013533268A/ja active Pending
- 2011-07-15 ES ES201390009A patent/ES2445846R1/es active Pending
- 2011-07-15 BR BR112013001299A patent/BR112013001299A2/pt not_active Application Discontinuation
- 2011-07-15 KR KR1020187032943A patent/KR20180127515A/ko not_active Ceased
- 2011-07-15 GB GB1707872.6A patent/GB2552405B/en not_active Expired - Fee Related
- 2011-07-15 GB GB1302924.4A patent/GB2496799B/en not_active Expired - Fee Related
- 2011-07-15 FI FI20135152A patent/FI20135152L/fi not_active Application Discontinuation
- 2011-07-15 NZ NZ606964A patent/NZ606964A/en not_active IP Right Cessation
- 2011-07-15 EE EEP201300007A patent/EE05761B1/et not_active IP Right Cessation
- 2011-07-15 DE DE112011102396T patent/DE112011102396T5/de not_active Withdrawn
- 2011-07-15 PE PE2013000114A patent/PE20130815A1/es not_active Application Discontinuation
- 2011-07-15 SE SE1350212A patent/SE1350212A1/sv unknown
- 2011-07-15 FR FR1156480A patent/FR2962913A1/fr not_active Withdrawn
- 2011-07-15 CA CA2805961A patent/CA2805961A1/en not_active Abandoned
- 2011-07-15 EA EA201300124A patent/EA029847B1/ru not_active IP Right Cessation
- 2011-07-15 PH PH1/2013/500140A patent/PH12013500140A1/en unknown
- 2011-07-15 CZ CZ20130124A patent/CZ2013124A3/cs unknown
- 2011-07-15 KR KR1020137004330A patent/KR20130103486A/ko not_active Ceased
- 2011-07-15 US US13/135,891 patent/US8617555B2/en active Active
- 2011-07-15 AU AU2011281240A patent/AU2011281240B2/en not_active Ceased
- 2011-07-15 EP EP19213849.3A patent/EP3693018A1/en not_active Withdrawn
- 2011-07-15 MX MX2013000804A patent/MX2013000804A/es active IP Right Grant
- 2011-07-15 CN CN2011800454899A patent/CN103118707A/zh active Pending
- 2011-07-15 WO PCT/IB2011/002177 patent/WO2012010966A2/en not_active Ceased
- 2011-07-15 MY MYPI2013000225A patent/MY160979A/en unknown
- 2011-07-21 AR ARP110102642A patent/AR082312A1/es not_active Application Discontinuation
-
2013
- 2013-01-21 CL CL2013000200A patent/CL2013000200A1/es unknown
- 2013-02-18 NO NO20130265A patent/NO20130265A1/no not_active Application Discontinuation
- 2013-02-19 DK DKPA201370089A patent/DK201370089A/da not_active Application Discontinuation
- 2013-02-19 LT LT2013018A patent/LT5980B/lt not_active IP Right Cessation
-
2016
- 2016-07-01 JP JP2016131729A patent/JP2016222684A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1547612A1 (en) * | 2002-08-02 | 2005-06-29 | Oleg Iliich Epshtein | Medicinal agent and method for curing erectile dysfunction |
| EP2036574A1 (en) * | 2006-06-06 | 2009-03-18 | Oleg Iliich Epshtein | Medicinal agent for treating fatness, diabetes, and diseases associated with impaired glucose tolerance |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20210715 |