GB2493540A - Agents for stimulating hair growth in mammals - Google Patents

Agents for stimulating hair growth in mammals Download PDF

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Publication number
GB2493540A
GB2493540A GB1113770.0A GB201113770A GB2493540A GB 2493540 A GB2493540 A GB 2493540A GB 201113770 A GB201113770 A GB 201113770A GB 2493540 A GB2493540 A GB 2493540A
Authority
GB
United Kingdom
Prior art keywords
alopecia
composition according
polypeptide
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB1113770.0A
Other languages
English (en)
Other versions
GB201113770D0 (en
Inventor
Pontus Duner
Anna Hultgardh Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Follicum AB
Original Assignee
Follicum AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Follicum AB filed Critical Follicum AB
Priority to GB1113770.0A priority Critical patent/GB2493540A/en
Publication of GB201113770D0 publication Critical patent/GB201113770D0/en
Priority to HK14111213.2A priority patent/HK1197540B/en
Priority to PL16169698T priority patent/PL3087999T3/pl
Priority to PL12768879T priority patent/PL2741761T3/pl
Priority to EP12768879.4A priority patent/EP2741761B1/en
Priority to JP2014524449A priority patent/JP6049718B2/ja
Priority to ES12768879.4T priority patent/ES2576299T3/es
Priority to TR2019/10685T priority patent/TR201910685T4/tr
Priority to ES16169698T priority patent/ES2740826T3/es
Priority to US14/237,108 priority patent/US9381149B2/en
Priority to CA2844749A priority patent/CA2844749C/en
Priority to DK12768879.4T priority patent/DK2741761T3/en
Priority to KR1020147006108A priority patent/KR101992282B1/ko
Priority to PCT/GB2012/051955 priority patent/WO2013021212A2/en
Priority to CN201280049850.XA priority patent/CN103930125B/zh
Priority to BR112014003051-0A priority patent/BR112014003051B1/pt
Priority to RU2014108819/10A priority patent/RU2604797C2/ru
Priority to DK16169698.4T priority patent/DK3087999T3/da
Priority to EP16169698.4A priority patent/EP3087999B1/en
Priority to AU2012293448A priority patent/AU2012293448B2/en
Publication of GB2493540A publication Critical patent/GB2493540A/en
Priority to US15/184,290 priority patent/US10137169B2/en
Priority to US16/176,201 priority patent/US10517932B2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/18—Materials or treatment for tissue regeneration for hair reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Birds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
GB1113770.0A 2011-08-10 2011-08-10 Agents for stimulating hair growth in mammals Withdrawn GB2493540A (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
GB1113770.0A GB2493540A (en) 2011-08-10 2011-08-10 Agents for stimulating hair growth in mammals
AU2012293448A AU2012293448B2 (en) 2011-08-10 2012-08-10 Novel compositions and uses thereof
CA2844749A CA2844749C (en) 2011-08-10 2012-08-10 Novel compositions and uses thereof
KR1020147006108A KR101992282B1 (ko) 2011-08-10 2012-08-10 불활성화된 rgd 도메인을 갖는 변형된 오스테오폰틴 펩티드 및 이의 용도
PL12768879T PL2741761T3 (pl) 2011-08-10 2012-08-10 Zmodyfikowane peptydy osteopontyny ze zdezaktywowaną domeną rgd
EP12768879.4A EP2741761B1 (en) 2011-08-10 2012-08-10 Modified osteopontin peptides having an inactivated rgd domain
JP2014524449A JP6049718B2 (ja) 2011-08-10 2012-08-10 新規組成物及びその使用
ES12768879.4T ES2576299T3 (es) 2011-08-10 2012-08-10 Péptidos de osteopontina modificados que tienen un dominio RGD inactivado
TR2019/10685T TR201910685T4 (tr) 2011-08-10 2012-08-10 Bir inaktive RGD bölgesine sahip modifiye osteopontin peptitleri ve bunların kullanımları.
ES16169698T ES2740826T3 (es) 2011-08-10 2012-08-10 Péptidos de osteopontina modificados que tienen un dominio RGD inactivado y usos de estos
US14/237,108 US9381149B2 (en) 2011-08-10 2012-08-10 Compositions and uses thereof
HK14111213.2A HK1197540B (en) 2011-08-10 2012-08-10 Modified osteopontin peptides having an inactivated rgd domain
DK12768879.4T DK2741761T3 (en) 2011-08-10 2012-08-10 Modified osteopontin polypeptides which have an inactivated RGD domain
PL16169698T PL3087999T3 (pl) 2011-08-10 2012-08-10 Zmodyfikowane peptydy osteopontyny ze zdezaktywowaną domeną rgd i ich zastosowanie
PCT/GB2012/051955 WO2013021212A2 (en) 2011-08-10 2012-08-10 Novel compositions and uses thereof
CN201280049850.XA CN103930125B (zh) 2011-08-10 2012-08-10 具有失活rgd域的修饰的骨桥蛋白肽及其用途
BR112014003051-0A BR112014003051B1 (pt) 2011-08-10 2012-08-10 Polipeptídeo, composição para estimular o crescimento de cabelo e uso dos mesmos
RU2014108819/10A RU2604797C2 (ru) 2011-08-10 2012-08-10 Новые композиции и их применение
DK16169698.4T DK3087999T3 (da) 2011-08-10 2012-08-10 Modificerede osteopontinpeptider med et inaktiveret RGD-domæne og anvendelser deraf
EP16169698.4A EP3087999B1 (en) 2011-08-10 2012-08-10 Modified osteopontin peptides having an inactivated rgd domain and uses thereof
US15/184,290 US10137169B2 (en) 2011-08-10 2016-06-16 Compositions and uses thereof
US16/176,201 US10517932B2 (en) 2011-08-10 2018-10-31 Compositions and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1113770.0A GB2493540A (en) 2011-08-10 2011-08-10 Agents for stimulating hair growth in mammals

Publications (2)

Publication Number Publication Date
GB201113770D0 GB201113770D0 (en) 2011-09-21
GB2493540A true GB2493540A (en) 2013-02-13

Family

ID=44735704

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1113770.0A Withdrawn GB2493540A (en) 2011-08-10 2011-08-10 Agents for stimulating hair growth in mammals

Country Status (15)

Country Link
US (3) US9381149B2 (enExample)
EP (2) EP2741761B1 (enExample)
JP (1) JP6049718B2 (enExample)
KR (1) KR101992282B1 (enExample)
CN (1) CN103930125B (enExample)
AU (1) AU2012293448B2 (enExample)
BR (1) BR112014003051B1 (enExample)
CA (1) CA2844749C (enExample)
DK (2) DK2741761T3 (enExample)
ES (2) ES2740826T3 (enExample)
GB (1) GB2493540A (enExample)
PL (2) PL2741761T3 (enExample)
RU (1) RU2604797C2 (enExample)
TR (1) TR201910685T4 (enExample)
WO (1) WO2013021212A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220273765A1 (en) * 2019-04-24 2022-09-01 Follicum Ab Topical formulation

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2493540A (en) 2011-08-10 2013-02-13 Follicum Ab Agents for stimulating hair growth in mammals
GB201406989D0 (en) * 2014-04-17 2014-06-04 Follicum Ab Novel treatments
JP6548126B2 (ja) * 2014-11-27 2019-07-24 国立大学法人大阪大学 Iii型コラーゲン産生促進剤
KR101906557B1 (ko) * 2015-08-06 2018-10-11 서울대학교산학협력단 합성 펩타이드를 이용한 유도만능줄기세포의 제조방법
EP3600108A4 (en) * 2017-03-23 2021-01-06 The Regents of the University of California STIMULATION OF HAIR GROWTH BY SENESCENCE CELLS AND SENESCENCE-ASSOCIATED SECRETORIC PHENOTYPE
AU2018262805B2 (en) * 2017-05-04 2022-02-17 Follicum Ab Peptides for treatment of diabetes
KR102091567B1 (ko) * 2018-06-15 2020-03-20 인하대학교 산학협력단 오스테오폰틴 단백질 단편을 유효성분으로 함유하는 뇌손상 예방 또는 치료용 약학 조성물
US20220002343A1 (en) * 2018-11-07 2022-01-06 Follicum Ab Peptide fragments for treatment of diabetes
EP4110461A4 (en) * 2020-02-25 2024-05-01 Amplifica, Inc. COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH
AU2022335599A1 (en) * 2021-08-25 2024-03-07 Amplifica Holdings Group, Inc. Compositions and methods for stimulating hair growth
WO2023218095A1 (en) * 2022-05-13 2023-11-16 Coegin Pharma Ab Agents for stimulating tissue regeneration
CN119300852A (zh) * 2022-05-13 2025-01-10 科京制药公司 诱导血管形成的药剂
AU2024311323C1 (en) * 2023-06-20 2026-06-11 Amplifica Holdings Group, Inc. Compositions and methods for stimulating hair growth

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WO2008086449A2 (en) * 2007-01-09 2008-07-17 Oregon Health & Science University Synthetic osteopontin peptides and methods of use

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220273765A1 (en) * 2019-04-24 2022-09-01 Follicum Ab Topical formulation

Also Published As

Publication number Publication date
ES2576299T3 (es) 2016-07-06
EP2741761A2 (en) 2014-06-18
BR112014003051A2 (pt) 2019-04-02
WO2013021212A3 (en) 2014-04-17
JP2014525394A (ja) 2014-09-29
CN103930125A (zh) 2014-07-16
PL2741761T3 (pl) 2017-01-31
DK2741761T3 (en) 2016-08-15
EP3087999A1 (en) 2016-11-02
TR201910685T4 (tr) 2019-08-21
EP3087999B1 (en) 2019-05-08
KR20140083977A (ko) 2014-07-04
DK3087999T3 (da) 2019-07-29
WO2013021212A2 (en) 2013-02-14
EP2741761B1 (en) 2016-05-18
BR112014003051B1 (pt) 2022-01-04
US9381149B2 (en) 2016-07-05
AU2012293448A1 (en) 2014-02-27
US20190192631A1 (en) 2019-06-27
KR101992282B1 (ko) 2019-06-24
US10137169B2 (en) 2018-11-27
CA2844749A1 (en) 2013-02-14
ES2740826T3 (es) 2020-02-06
US10517932B2 (en) 2019-12-31
GB201113770D0 (en) 2011-09-21
HK1197540A1 (zh) 2015-01-23
JP6049718B2 (ja) 2016-12-21
US20150018273A1 (en) 2015-01-15
CN103930125B (zh) 2017-11-03
AU2012293448B2 (en) 2016-04-07
PL3087999T3 (pl) 2019-09-30
RU2604797C2 (ru) 2016-12-10
US20160317620A1 (en) 2016-11-03
CA2844749C (en) 2020-07-14
RU2014108819A (ru) 2015-09-20

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