GB2469894B - Peptides for use in treating allergy to grass pollen - Google Patents

Peptides for use in treating allergy to grass pollen

Info

Publication number
GB2469894B
GB2469894B GB1001954A GB201001954A GB2469894B GB 2469894 B GB2469894 B GB 2469894B GB 1001954 A GB1001954 A GB 1001954A GB 201001954 A GB201001954 A GB 201001954A GB 2469894 B GB2469894 B GB 2469894B
Authority
GB
United Kingdom
Prior art keywords
peptides
grass pollen
treating allergy
allergy
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB1001954A
Other languages
English (en)
Other versions
GB2469894A (en
GB201001954D0 (en
Inventor
Rod Hafner
Paul Laidler
Guy Layton
Mark Larche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Niox Healthcare Ltd
Original Assignee
Circassia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0901927.4A external-priority patent/GB0901927D0/en
Priority claimed from GB0901928A external-priority patent/GB0901928D0/en
Priority claimed from GB0912578A external-priority patent/GB0912578D0/en
Priority claimed from PCT/GB2009/001995 external-priority patent/WO2010018384A1/en
Priority claimed from GB0917871A external-priority patent/GB0917871D0/en
Application filed by Circassia Ltd filed Critical Circassia Ltd
Publication of GB201001954D0 publication Critical patent/GB201001954D0/en
Publication of GB2469894A publication Critical patent/GB2469894A/en
Application granted granted Critical
Publication of GB2469894B publication Critical patent/GB2469894B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
GB1001954A 2009-02-05 2010-02-05 Peptides for use in treating allergy to grass pollen Expired - Fee Related GB2469894B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0901927.4A GB0901927D0 (en) 2009-02-05 2009-02-05 Peptide for IL10 production
GB0901928A GB0901928D0 (en) 2009-02-05 2009-02-05 Peptides for vaccine
GB0912578A GB0912578D0 (en) 2009-07-20 2009-07-20 Peptide for IL-10 production
PCT/GB2009/001995 WO2010018384A1 (en) 2008-08-15 2009-08-14 T-cell antigen peptide from allergen for stimulation of il-10 production
GB0917871A GB0917871D0 (en) 2009-10-12 2009-10-12 Peptides for vaccine

Publications (3)

Publication Number Publication Date
GB201001954D0 GB201001954D0 (en) 2010-03-24
GB2469894A GB2469894A (en) 2010-11-03
GB2469894B true GB2469894B (en) 2011-09-07

Family

ID=42082585

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1001954A Expired - Fee Related GB2469894B (en) 2009-02-05 2010-02-05 Peptides for use in treating allergy to grass pollen

Country Status (23)

Country Link
US (2) US8753644B2 (enExample)
EP (2) EP2393830B8 (enExample)
JP (2) JP5746053B2 (enExample)
KR (1) KR20110111307A (enExample)
CN (2) CN102307893B (enExample)
AU (1) AU2010212193B2 (enExample)
BR (1) BRPI1008802A2 (enExample)
CA (1) CA2751500A1 (enExample)
DK (1) DK2393830T3 (enExample)
EA (1) EA020792B1 (enExample)
ES (1) ES2532759T3 (enExample)
GB (1) GB2469894B (enExample)
HK (1) HK1212358A1 (enExample)
HR (1) HRP20150317T1 (enExample)
IL (1) IL214257A (enExample)
MX (1) MX2011008179A (enExample)
NZ (1) NZ594268A (enExample)
PL (1) PL2393830T3 (enExample)
PT (1) PT2393830E (enExample)
SG (1) SG173523A1 (enExample)
SI (1) SI2393830T1 (enExample)
WO (1) WO2010089554A1 (enExample)
ZA (1) ZA201105436B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2393830T1 (sl) * 2009-02-05 2015-04-30 Circassia Limited Travni peptidi za cepivo
CN107320734A (zh) * 2011-04-29 2017-11-07 西莱克塔生物科技公司 从合成纳米载体中控制释放免疫抑制剂
CN105307641A (zh) 2013-05-03 2016-02-03 西莱克塔生物科技公司 用于降低不期望体液免疫应答的给药组合
EA201790551A1 (ru) 2014-09-07 2017-07-31 Селекта Байосайенсиз, Инк. Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору
WO2017004561A1 (en) 2015-07-01 2017-01-05 Alk-Abelló A/S Peptide combinations and uses thereof for treating grass allergy
EP4599848A3 (en) 2017-03-11 2025-12-03 Cartesian Therapeutics, Inc. Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
EP3672600A4 (en) 2017-08-21 2021-05-19 Glycom A/S SYNTHETIC COMPOSITION TO REDUCE ALLERGY SYMPTOMS
CN108802216B (zh) * 2018-05-23 2021-04-16 山东出入境检验检疫局检验检疫技术中心 一种使用区域敏感性蛋白组和/或多肽组鉴别刺参产地的方法
US12553041B2 (en) 2019-06-04 2026-02-17 Cartesian Therapeutics Inc. Formulations and doses of pegylated uricase

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2003024998A1 (en) * 2001-09-18 2003-03-27 Monash University T cell epitopes of the cyn d 1 allergen from bermuda grass pollen

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US5480972A (en) 1992-10-30 1996-01-02 The University Of Melbourne Allergenic proteins from Johnson grass pollen
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FI960629L (fi) * 1993-08-13 1996-04-12 Immulogic Pharma Corp Raiheinäsiitepöly allergeenin T-soluepitoopit
US5968526A (en) 1994-04-14 1999-10-19 Immulogic Pharamaceutical Corporation T cell epitopes of the major allergens from Dermatophagoides (house dust mite)
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IL115744A (en) 1994-10-27 2000-07-16 Akzo Nobel Nv Peptides comprising a subsequence of human cartilage glycoprotein - 39
AT402505B (de) 1995-08-02 1997-06-25 Biomay Prod & Handel Rekombinantes 60 kda pflanzliches panallergen (kofaktor-unabhängige phosphoglyceratmutase; e.c. 5.4.2.1.)
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Publication number Priority date Publication date Assignee Title
WO2003024998A1 (en) * 2001-09-18 2003-03-27 Monash University T cell epitopes of the cyn d 1 allergen from bermuda grass pollen

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Clin Exp Allergy; Vol 28, pp 1538-1548 (1998). MÜller et al. "Mapping of T cell epitopes of Phl p 5: evidence for crossreacting and non-crossreacting T cell epitopes..." *
Clin Exp Allergy; Vol 39, pp 387-393 (2008). Malling et al. "Efficacy and safety of 5-grass pollen sublingual immunotherapy tablets in patients with different clinical profiles of allergic rhinoconjunctivitis" *
Eur J Biochem; Vol 247-223 (1997). Gehlhar et al. "Investigation of different recombinant isoforms of grass group-V allergens (timothy grass pollen) isolated by low-stringency cDNA hybridization" *
Immunology, Vol. 87, pp 283-290 (1996). Zhang, et al. "Multiple B- and T-cell epitopes on a major allergen of Kentucky blue grass pollen" *
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J Allergy Clin Immunol; Vol 120, pp 1338-1345 (2010). Didier et al. "Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5-grass pollen tablet for seasonal allergic rhinitis" *

Also Published As

Publication number Publication date
PL2393830T3 (pl) 2015-07-31
HRP20150317T1 (hr) 2015-04-24
US8753644B2 (en) 2014-06-17
IL214257A (en) 2016-06-30
JP2012516693A (ja) 2012-07-26
EP2393830B8 (en) 2015-03-18
JP5746053B2 (ja) 2015-07-08
ES2532759T3 (es) 2015-03-31
WO2010089554A1 (en) 2010-08-12
CN103784952A (zh) 2014-05-14
SG173523A1 (en) 2011-09-29
CA2751500A1 (en) 2010-08-12
WO2010089554A8 (en) 2011-10-06
BRPI1008802A2 (pt) 2016-03-08
HK1212358A1 (en) 2016-06-10
US20140302071A1 (en) 2014-10-09
AU2010212193B2 (en) 2015-05-14
PT2393830E (pt) 2015-04-23
EP2393830B1 (en) 2015-01-28
MX2011008179A (es) 2011-09-09
CN102307893A (zh) 2012-01-04
CN103784952B (zh) 2016-08-17
SI2393830T1 (sl) 2015-04-30
EA020792B1 (ru) 2015-01-30
KR20110111307A (ko) 2011-10-10
EA201171001A1 (ru) 2012-02-28
NZ594268A (en) 2013-05-31
ZA201105436B (en) 2012-09-26
AU2010212193A1 (en) 2011-08-18
DK2393830T3 (en) 2015-04-27
CN102307893B (zh) 2014-03-26
EP2393830A1 (en) 2011-12-14
US20120148612A1 (en) 2012-06-14
GB2469894A (en) 2010-11-03
JP6215252B2 (ja) 2017-10-18
IL214257A0 (en) 2011-09-27
EP2891662A1 (en) 2015-07-08
JP2015180646A (ja) 2015-10-15
GB201001954D0 (en) 2010-03-24

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