BRPI1008802A2 - composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição - Google Patents

composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição

Info

Publication number
BRPI1008802A2
BRPI1008802A2 BRPI1008802A BRPI1008802A BRPI1008802A2 BR PI1008802 A2 BRPI1008802 A2 BR PI1008802A2 BR PI1008802 A BRPI1008802 A BR PI1008802A BR PI1008802 A BRPI1008802 A BR PI1008802A BR PI1008802 A2 BRPI1008802 A2 BR PI1008802A2
Authority
BR
Brazil
Prior art keywords
composition
toleration
vector
prevention
treatment
Prior art date
Application number
BRPI1008802A
Other languages
English (en)
Portuguese (pt)
Inventor
Guy Layton
Mark Larche
Paul Laidler
Rod Hafner
Original Assignee
Circassia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0901927.4A external-priority patent/GB0901927D0/en
Priority claimed from GB0901928A external-priority patent/GB0901928D0/en
Priority claimed from GB0912578A external-priority patent/GB0912578D0/en
Priority claimed from PCT/GB2009/001995 external-priority patent/WO2010018384A1/en
Priority claimed from GB0917871A external-priority patent/GB0917871D0/en
Application filed by Circassia Ltd filed Critical Circassia Ltd
Publication of BRPI1008802A2 publication Critical patent/BRPI1008802A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
BRPI1008802A 2009-02-05 2010-02-05 composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição BRPI1008802A2 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB0901927.4A GB0901927D0 (en) 2009-02-05 2009-02-05 Peptide for IL10 production
GB0901928A GB0901928D0 (en) 2009-02-05 2009-02-05 Peptides for vaccine
GB0912578A GB0912578D0 (en) 2009-07-20 2009-07-20 Peptide for IL-10 production
PCT/GB2009/001995 WO2010018384A1 (en) 2008-08-15 2009-08-14 T-cell antigen peptide from allergen for stimulation of il-10 production
GB0917871A GB0917871D0 (en) 2009-10-12 2009-10-12 Peptides for vaccine
PCT/GB2010/000198 WO2010089554A1 (en) 2009-02-05 2010-02-05 Peptides for vaccine

Publications (1)

Publication Number Publication Date
BRPI1008802A2 true BRPI1008802A2 (pt) 2016-03-08

Family

ID=42082585

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1008802A BRPI1008802A2 (pt) 2009-02-05 2010-02-05 composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição

Country Status (23)

Country Link
US (2) US8753644B2 (enExample)
EP (2) EP2891662A1 (enExample)
JP (2) JP5746053B2 (enExample)
KR (1) KR20110111307A (enExample)
CN (2) CN103784952B (enExample)
AU (1) AU2010212193B2 (enExample)
BR (1) BRPI1008802A2 (enExample)
CA (1) CA2751500A1 (enExample)
DK (1) DK2393830T3 (enExample)
EA (1) EA020792B1 (enExample)
ES (1) ES2532759T3 (enExample)
GB (1) GB2469894B (enExample)
HK (1) HK1212358A1 (enExample)
HR (1) HRP20150317T1 (enExample)
IL (1) IL214257A (enExample)
MX (1) MX2011008179A (enExample)
NZ (1) NZ594268A (enExample)
PL (1) PL2393830T3 (enExample)
PT (1) PT2393830E (enExample)
SG (1) SG173523A1 (enExample)
SI (1) SI2393830T1 (enExample)
WO (1) WO2010089554A1 (enExample)
ZA (1) ZA201105436B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103784952B (zh) * 2009-02-05 2016-08-17 切尔卡西亚有限公司 用于疫苗的草肽
CN103501812A (zh) 2011-04-29 2014-01-08 西莱克塔生物科技公司 用于过敏症治疗的致耐受性合成纳米载体
CA2910584A1 (en) 2013-05-03 2014-11-06 Selecta Biosciences, Inc. Use of immunosuppressants attached to synthetic nanocarriers to enhance levels of cd4+ regulatory t cells
WO2016037163A1 (en) 2014-09-07 2016-03-10 Selecta Biosciences, Inc. Methods and compositions for attenuating gene therapy anti-viral transfer vector immune responses
US11013781B2 (en) 2015-07-01 2021-05-25 Alk-Abelló As Peptide combinations and uses thereof for treating grass allergy
EP3592389B1 (en) 2017-03-11 2025-05-07 Cartesian Therapeutics, Inc. Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
US11524019B2 (en) 2017-08-21 2022-12-13 Glycom A/S Synthetic composition for reducing allergy symptoms
CN108802216B (zh) * 2018-05-23 2021-04-16 山东出入境检验检疫局检验检疫技术中心 一种使用区域敏感性蛋白组和/或多肽组鉴别刺参产地的方法

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340729C (en) 1988-03-23 1999-09-07 Mohan Bir Singh Ryegrass pollen allergen
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
DE69128039T2 (de) 1990-08-17 1998-03-05 Penelope Smith Allergene aus roggenspreupollen
WO1992016554A1 (en) 1991-03-14 1992-10-01 The University Of Melbourne Protein allergens of the species cynodon dactylon
WO1994001560A1 (en) 1991-07-12 1994-01-20 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
NZ243956A (en) 1991-08-16 1997-05-26 Univ Melbourne Ryegrass pollen antigen (lol p ib), nucleic acid encoding it, host cells, vectors, monoclonal antibodies and pharmaceutical for treating ryegrass allergy
EP0668915A1 (en) 1991-11-15 1995-08-30 The University Of Melbourne Protein allergens of the species cynodon dactylon
US6441157B1 (en) 1991-11-15 2002-08-27 University Of Melbourne Nucleic acid sequences encoding protein allergens of the species Cynodon dactylon
NZ328940A (en) 1992-08-14 1999-05-28 Univ Melbourne Methods and use t cell epitopes of lol p v ryegrass pollen antigens
US6214358B1 (en) 1992-10-30 2001-04-10 Immulogic Pharamaceutical Corp. Protein allergens of the species Cynodon dactylon
US5480972A (en) 1992-10-30 1996-01-02 The University Of Melbourne Allergenic proteins from Johnson grass pollen
FI954269A0 (fi) 1993-03-12 1995-09-12 Immunologic Pharma Corp Raiheinäsiitepölyallergeenin T-soluepitoopit
JPH09504167A (ja) * 1993-08-13 1997-04-28 イミュロジック ファーマスーティカル コーポレイション ドクムギ花粉アレルゲンのｔ細胞エピトープ
US5820862A (en) 1994-04-14 1998-10-13 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
GB9412714D0 (en) 1994-06-24 1994-08-17 Lewin Ian V T cill epitopes
WO1996003106A2 (en) * 1994-07-26 1996-02-08 University Of Manitoba Allergenic peptides derived from poa pratensis
US7112333B1 (en) * 1994-08-05 2006-09-26 Heska Corporation T cell epitopes of ryegrass pollen allergen
IL115744A (en) 1994-10-27 2000-07-16 Akzo Nobel Nv Peptides comprising a subsequence of human cartilage glycoprotein - 39
AT402505B (de) 1995-08-02 1997-06-25 Biomay Prod & Handel Rekombinantes 60 kda pflanzliches panallergen (kofaktor-unabhängige phosphoglyceratmutase; e.c. 5.4.2.1.)
JP2002500198A (ja) 1998-01-09 2002-01-08 サーカシア リミテッド 脱感作のための方法及び組成物
DE19823097A1 (de) * 1998-05-22 1999-11-25 Max Planck Gesellschaft Mittel gegen saisonale Typ-I-Allergien und bakterielle Infektionen
US6989146B2 (en) 2000-08-09 2006-01-24 The Regents Of The University Of California Stress proteins and peptides and methods of use thereof
AUPR775401A0 (en) * 2001-09-18 2001-10-11 Monash University Novel Epitopes and Uses Thereof
JP4874522B2 (ja) 2001-12-05 2012-02-15 サーカッシア リミテッド 免疫療法および系
AUPS148202A0 (en) * 2002-04-02 2002-05-09 Monash University Immunotherapeutic and immunoprophylactic reagents
AU2003228133A1 (en) 2002-04-22 2003-11-03 Umc Utrecht Holding B.V. Reduction of unwanted immune reactions
GB0210741D0 (en) 2002-05-10 2002-06-19 Medical Res Council Methods of therapy
GB0308988D0 (en) 2003-04-17 2003-05-28 Univ Singapore Molecule
DE102004035337A1 (de) * 2004-07-21 2006-03-16 Merck Patent Gmbh Varianten der Gruppe 1-Allergene aus Poaceae mit reduzierter Allergenität und erhaltener T-Zellreaktivität
WO2006075253A2 (en) 2005-01-11 2006-07-20 Commissariat A L'energie Atomique Peptides for desensitizing subjects allergic to dog hair and dander and compositions containing said peptides.
US20090130130A1 (en) 2005-06-10 2009-05-21 National University Of Singapore Mutant allergen(s)
DE202005009990U1 (de) * 2005-06-25 2006-11-02 Hengst Gmbh & Co.Kg Vorrichtung zum Abscheiden von Ölteilchen aus dem Kurbelgehäuseentlüftungsgas einer Brennkraftmaschine
US20070092532A1 (en) 2005-10-25 2007-04-26 Board Of Trustees Operating Michigan State University Arthritis vaccines and methods
ES2405552T3 (es) 2005-11-29 2013-05-31 Actogenix N.V. Inducción de tolerancia mucosa a antiantígenos de células beta de islotes pancreáticos
AT503690A1 (de) * 2006-06-09 2007-12-15 Biomay Ag Hypoallergene moleküle
EP2156183B1 (en) 2007-05-09 2013-08-07 Circassia Limited Prognostic assay for determining t cell response to hla antigens and use thereof in field of tissue transplantation
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
ES2402956T3 (es) 2007-08-15 2013-05-10 Circassia Limited Péptido con formación de dímeros reducida
EP2042193A1 (en) 2007-09-28 2009-04-01 Biomay AG RNA Vaccines
EP2331124A1 (en) 2008-08-15 2011-06-15 Circassia Limited T-cell antigen peptide from allergen for stimulation of il-10 production
CN103784952B (zh) * 2009-02-05 2016-08-17 切尔卡西亚有限公司 用于疫苗的草肽

Also Published As

Publication number Publication date
SI2393830T1 (sl) 2015-04-30
DK2393830T3 (en) 2015-04-27
EP2393830B8 (en) 2015-03-18
JP6215252B2 (ja) 2017-10-18
EP2393830A1 (en) 2011-12-14
CN102307893B (zh) 2014-03-26
CN103784952B (zh) 2016-08-17
HRP20150317T1 (hr) 2015-04-24
AU2010212193A1 (en) 2011-08-18
KR20110111307A (ko) 2011-10-10
JP2012516693A (ja) 2012-07-26
CN103784952A (zh) 2014-05-14
GB2469894A (en) 2010-11-03
JP2015180646A (ja) 2015-10-15
US20140302071A1 (en) 2014-10-09
US20120148612A1 (en) 2012-06-14
PT2393830E (pt) 2015-04-23
PL2393830T3 (pl) 2015-07-31
CN102307893A (zh) 2012-01-04
WO2010089554A1 (en) 2010-08-12
NZ594268A (en) 2013-05-31
MX2011008179A (es) 2011-09-09
GB201001954D0 (en) 2010-03-24
IL214257A (en) 2016-06-30
WO2010089554A8 (en) 2011-10-06
EP2891662A1 (en) 2015-07-08
ZA201105436B (en) 2012-09-26
IL214257A0 (en) 2011-09-27
GB2469894B (en) 2011-09-07
AU2010212193B2 (en) 2015-05-14
ES2532759T3 (es) 2015-03-31
HK1212358A1 (en) 2016-06-10
JP5746053B2 (ja) 2015-07-08
EA020792B1 (ru) 2015-01-30
EP2393830B1 (en) 2015-01-28
SG173523A1 (en) 2011-09-29
US8753644B2 (en) 2014-06-17
CA2751500A1 (en) 2010-08-12
EA201171001A1 (ru) 2012-02-28

Similar Documents

Publication Publication Date Title
IL269858A (en) Pyridone and aza-pyridone compounds, pharmaceutical composition and kits comprising the same and uses thereof
BR112014010177A2 (pt) composto, composição farmacêutica, uso do composto, e, método para a profilaxia ou tratamento de um estado ou uma condição de doença
BRPI1008802A2 (pt) composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição
WO2012024620A3 (en) Autotaxin inhibitors and uses thereof
BR112014010206A2 (pt) composto, composição farmacêutica, uso de composto, e, método para a profilaxia ou tratamento de um estado ou condição de doença
HUE053113T2 (hu) Bardoxolon-metil 2,2-difluorpropionamid-származéka, annak gyógyszerkészítményei és polimorfjai bizonyos betegségek kezelésében történõ alkalmazásra
BRPI1014865A2 (pt) "composição e formulação farmacêutica comreendendo derivados de nitrocatecol, e, método para fabricar uma composição ou formulação farmacêutica"
BR112015003397A2 (pt) composto, composição farmacêutica, uso do composto e método para tratar uma doença ou condição mediada por rorgammat em um paciente.
BR112014010179A8 (pt) composto, composição farmacêutica, uso de um composto, e, método para a profilaxia ou tratamento de um estado ou condição
CL2013003372A1 (es) Compuestos derivados de espiro-[1,3]-oxacinas y espiro-[1,4]-oxacepinas, inhibidores de bace1 y/o bace2; composicion farmaceutica; procedimiento para prepararlos; y su uso en el tratamiento y/o la profilaxis de la enfermedad de alzheimer y diabetes.
HUE037747T2 (hu) Nanostrukturált aprepirant készítmények, eljárások azok elõállítására és az azokat tartalmazó gyógyászati készítmények
BR112015003332A2 (pt) composto, composição farmacêutica, uso do composto e método para tratar uma doença ou condição mediada por rorgammat em um paciente
BR112015003398A2 (pt) composto, composição farmacêutica, uso do composto e método para tratar uma doença ou condição mediada por rorgammat em um paciente
IL233154A (en) Compounds, pharmaceuticals containing them and their uses
IL231536A (en) Indazole-3-carboxamides, pharmaceuticals containing them and their use in the treatment of diseases
CO6791606A2 (es) Composiciones y métodos para el tratamiento en aplicaciones clínicas de amplio espectro, no diferenciadas o combinadas
IL221940A (en) Small anti-infective compounds, pharmaceutical preparations containing them and their use in the preparation of drugs for the treatment of bacterial infections
BR112015011036A2 (pt) derivados de 2-amino-quinazolina substituídos heterocíclicos para o tratamento de infecções virais
WO2010069532A8 (en) Antibodies against human angiopoietin 2
BRPI1013984A2 (pt) composto , composição farmacêutica, método para tratamento ou profilaxia de uma doença ou condição, e, uso de um composto.
WO2012068441A3 (en) Intedanib salts and solid state forms thereof
HK1206028A1 (en) Phenicol antibacterials
IL235923B (en) Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical preparations thereof
CL2013001591A1 (es) Compuestos derivados de triazolopiridina; inhibidores de pde10a; proceso de obtencion; composicion farmaceutica; y uso en el tratamiento o profilaxis de trastornos psicoticos, esquizofrenia, ansiedad, entre otras enfermedades.
CL2014000849A1 (es) Compuestos derivados de benzilindazoles sustituido, inhibidores de la quinasa bub1; procedimiento de fabricacion; composicion farmaceutica; combinacion farmaceutica; y su uso en el tratamiento de enfermedades hiperproliferativas.

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2447 DE 28-11-2017 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.