GB231150A - - Google Patents
Info
- Publication number
- GB231150A GB231150A GB5502/25A GB550225A GB231150A GB 231150 A GB231150 A GB 231150A GB 5502/25 A GB5502/25 A GB 5502/25A GB 550225 A GB550225 A GB 550225A GB 231150 A GB231150 A GB 231150A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- ethyl ester
- barbituric
- ester
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
Barbituric acids substituted in the C.C-position with an unsaturated alicyclic group and an aliphatic hydrocarbon residue are prepared in known manner from the corresponding disubstituted malonic acid or cyanacetic acid or derivative thereof, or by introducing one of the groups into a barbituric acid substituted with respect to the other groups, or into an intermediate product for the preparation of these barbituric acids and converting the intermediate product obtained into a barbituric acid. The products possess hypnotic properties. According to the examples (1) D 2-cyclohexenylethylbarbituric acid is prepared by treating the sodium compound of monoethylmalonic ethyl ester with 1-brom-D 2-cyclohexene and reacting upon the resulting D 2-cyclohexenylethylmalonic ethyl ester with urea; D 2-cyclohexenylallylbarbituric acid is prepared similarly, by using monoallylmalonic acid ethyl ester instead of monoethylmalonic ethyl ester; (2) the sodium compound of D 1-cyclohexenylcyanacetic ethyl ester is treated with ethyl iodide and the resulting D 1-cyclohexenylethylcyanacetic ethyl ester then added to a solution obtained by boiling guanidine sulphate with sodium in alcohol, whereby D 1-cyclohexenylethylbarbituric acid is produced; D 1-methylcyclohexenyl- and D 1-cyclopentenyl-cyanacetic ester are transformed in the same way into D 1-methylcyclohexenylethyl- and D 1-cyclopentenylethyl-barbituric acids respectively. The Specification as open to inspection under Sect. 91 (3) (a) includes a detailed example of the production of D 1-cyclopentemylethyl-barbituric acid from cyclopentenylcyanacetic ester, ethyl bromide and guanidine sulphate. This subject-matter does not appear in the Specification as accepted.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE231150X | 1924-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB231150A true GB231150A (en) | 1926-01-14 |
Family
ID=5874160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5502/25A Expired GB231150A (en) | 1924-03-21 | 1925-02-27 |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB231150A (en) |
-
1925
- 1925-02-27 GB GB5502/25A patent/GB231150A/en not_active Expired
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