GB2211737B - Aqueous formulations containing a piperidinylcyclopentylheptenoic acid derivative - Google Patents

Aqueous formulations containing a piperidinylcyclopentylheptenoic acid derivative

Info

Publication number
GB2211737B
GB2211737B GB8829793A GB8829793A GB2211737B GB 2211737 B GB2211737 B GB 2211737B GB 8829793 A GB8829793 A GB 8829793A GB 8829793 A GB8829793 A GB 8829793A GB 2211737 B GB2211737 B GB 2211737B
Authority
GB
United Kingdom
Prior art keywords
acid derivative
formulations containing
aqueous formulations
piperidinylcyclopentylheptenoic
piperidinylcyclopentylheptenoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8829793A
Other languages
English (en)
Other versions
GB2211737A (en
GB8829793D0 (en
Inventor
Harry Finch
Anthony John Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878729823A external-priority patent/GB8729823D0/en
Priority claimed from GB888804422A external-priority patent/GB8804422D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of GB8829793D0 publication Critical patent/GB8829793D0/en
Publication of GB2211737A publication Critical patent/GB2211737A/en
Application granted granted Critical
Publication of GB2211737B publication Critical patent/GB2211737B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB8829793A 1987-12-22 1988-12-21 Aqueous formulations containing a piperidinylcyclopentylheptenoic acid derivative Expired - Fee Related GB2211737B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878729823A GB8729823D0 (en) 1987-12-22 1987-12-22 Complexes
GB888804422A GB8804422D0 (en) 1988-02-25 1988-02-25 Complexes

Publications (3)

Publication Number Publication Date
GB8829793D0 GB8829793D0 (en) 1989-02-15
GB2211737A GB2211737A (en) 1989-07-12
GB2211737B true GB2211737B (en) 1991-12-11

Family

ID=26293226

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8829793A Expired - Fee Related GB2211737B (en) 1987-12-22 1988-12-21 Aqueous formulations containing a piperidinylcyclopentylheptenoic acid derivative

Country Status (29)

Country Link
JP (1) JPH02210A (fr)
KR (1) KR890009402A (fr)
CN (1) CN1034132A (fr)
AT (1) AT395943B (fr)
AU (1) AU615245B2 (fr)
BE (1) BE1001704A3 (fr)
CA (1) CA1328078C (fr)
CH (1) CH676665A5 (fr)
DE (1) DE3843059A1 (fr)
DK (1) DK712888A (fr)
ES (1) ES2011727A6 (fr)
FI (1) FI885920A (fr)
FR (1) FR2624731B1 (fr)
GB (1) GB2211737B (fr)
GR (1) GR880100854A (fr)
HU (1) HU204700B (fr)
IE (1) IE61995B1 (fr)
IL (1) IL88764A0 (fr)
IT (1) IT1224835B (fr)
LU (1) LU87411A1 (fr)
MY (1) MY103952A (fr)
NL (1) NL8803126A (fr)
NO (1) NO885689L (fr)
NZ (1) NZ227446A (fr)
PH (1) PH24982A (fr)
PL (1) PL276595A1 (fr)
PT (1) PT89301B (fr)
SE (1) SE502288C2 (fr)
ZW (1) ZW18088A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814725D0 (en) * 1988-06-21 1988-07-27 Glaxo Group Ltd Medicaments
AU616571B2 (en) * 1988-10-28 1991-10-31 Shiseido Company Ltd. Cosmetic composition containing inclusion product with hydroxyalkylated cyclodextrin
IT1269578B (it) * 1994-04-22 1997-04-08 Chiesi Farma Spa Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base.
KR100825736B1 (ko) * 2005-12-07 2008-04-29 한국전자통신연구원 무선 xml 전자 서명 서비스 제공 장치 및 그 방법
KR100832740B1 (ko) * 2007-01-17 2008-05-27 한국과학기술원 분지쇄 아미노산 생성능이 개선된 변이 미생물 및 이를이용한 분지쇄 아미노산의 제조방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2097397A (en) * 1981-04-29 1982-11-03 Glaxo Group Ltd Aminocyclopentanol acids and esters as prostaglandin analogues and their preparation and pharmaceutical formulation
GB2127406A (en) * 1982-09-16 1984-04-11 Glaxo Group Ltd Piperidinylcyclopentanolheptenoic acid salt
WO1985002767A1 (fr) * 1983-12-21 1985-07-04 Janssen Pharmaceutica N.V. Compositions pharmaceutiques contenant des medicaments instables ou peu solubles dans l'eau et leurs procedes de preparation
JPS60150039A (ja) * 1984-01-17 1985-08-07 Minolta Camera Co Ltd 水陸両用固定焦点カメラ

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (fr) * 1970-06-10 1975-02-04
JPS5443569B2 (fr) * 1972-07-05 1979-12-20
HU181703B (en) * 1980-05-09 1983-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing aqueus solutuins of water insoluble or hardly soluble vitamines, steroides, localanesthetics, prostanoides and non-steroid and antiphlogistic agents
JPS58116423A (ja) * 1981-12-28 1983-07-11 Sumitomo Chem Co Ltd メタノプロスタサイクリン製剤組成物
JPS58192821A (ja) * 1982-04-30 1983-11-10 Dainippon Pharmaceut Co Ltd 脳神経細胞の酸素欠乏性疾患の治療剤
JPS5946228A (ja) * 1982-09-08 1984-03-15 Zeria Shinyaku Kogyo Kk 生物学的に活性な有機化合物の水溶性及びリンパ移行性薬剤の製造方法
JPS5973576A (ja) * 1982-09-16 1984-04-25 グラクソ・グル−プ・リミテツド ピペリジニルシクロペンタノ−ルヘプテン酸塩
DE3504044A1 (de) * 1985-02-04 1986-08-07 Schering AG, Berlin und Bergkamen, 1000 Berlin 9-halogenprostaglandin-clathrate und ihre verwendung als arzneimittel
JPS6327440A (ja) * 1986-07-18 1988-02-05 Sanraku Inc グルコシル化分岐シクロデキストリン含有組成物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2097397A (en) * 1981-04-29 1982-11-03 Glaxo Group Ltd Aminocyclopentanol acids and esters as prostaglandin analogues and their preparation and pharmaceutical formulation
GB2127406A (en) * 1982-09-16 1984-04-11 Glaxo Group Ltd Piperidinylcyclopentanolheptenoic acid salt
WO1985002767A1 (fr) * 1983-12-21 1985-07-04 Janssen Pharmaceutica N.V. Compositions pharmaceutiques contenant des medicaments instables ou peu solubles dans l'eau et leurs procedes de preparation
JPS60150039A (ja) * 1984-01-17 1985-08-07 Minolta Camera Co Ltd 水陸両用固定焦点カメラ

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Chem. Pharm. Bull.,28(7), 1975-80 (1980) *
J. Pharm. Sci. 67(12), 1665-8 (1978) *

Also Published As

Publication number Publication date
IE883820L (en) 1989-06-22
NL8803126A (nl) 1989-07-17
IT8848702A0 (it) 1988-12-21
FI885920A (fi) 1989-06-23
HUT50040A (en) 1989-12-28
PT89301A (pt) 1990-06-29
PH24982A (en) 1990-12-26
GB2211737A (en) 1989-07-12
NO885689L (no) 1989-06-23
AT395943B (de) 1993-04-26
AU615245B2 (en) 1991-09-26
IE61995B1 (en) 1994-12-14
HU204700B (en) 1992-02-28
SE502288C2 (sv) 1995-09-25
FR2624731A1 (fr) 1989-06-23
JPH02210A (ja) 1990-01-05
DE3843059A1 (de) 1989-07-13
DK712888D0 (da) 1988-12-21
KR890009402A (ko) 1989-08-01
SE8804607D0 (sv) 1988-12-21
IL88764A0 (en) 1989-07-31
PT89301B (pt) 1995-07-03
IT1224835B (it) 1990-10-24
CA1328078C (fr) 1994-03-29
ATA313088A (de) 1992-09-15
ES2011727A6 (es) 1990-02-01
CN1034132A (zh) 1989-07-26
GB8829793D0 (en) 1989-02-15
BE1001704A3 (fr) 1990-02-13
PL276595A1 (en) 1989-08-21
SE8804607L (sv) 1989-06-23
FR2624731B1 (fr) 1992-10-23
LU87411A1 (fr) 1989-07-07
NZ227446A (en) 1991-08-27
MY103952A (en) 1993-10-30
CH676665A5 (fr) 1991-02-28
GR880100854A (el) 1994-03-31
ZW18088A1 (en) 1989-07-26
DK712888A (da) 1989-06-23
AU2735688A (en) 1989-06-22
NO885689D0 (no) 1988-12-21

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19961221