IE883820L - Piperidinylcyclopentylheptenoic acids compositions - Google Patents

Piperidinylcyclopentylheptenoic acids compositions

Info

Publication number
IE883820L
IE883820L IE883820A IE382088A IE883820L IE 883820 L IE883820 L IE 883820L IE 883820 A IE883820 A IE 883820A IE 382088 A IE382088 A IE 382088A IE 883820 L IE883820 L IE 883820L
Authority
IE
Ireland
Prior art keywords
beta
alpha
piperidinylcyclopentylheptenoic
aqueous formulations
acids compositions
Prior art date
Application number
IE883820A
Other versions
IE61995B1 (en
Inventor
Harry Finch
Anthony John Phillips
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878729823A external-priority patent/GB8729823D0/en
Priority claimed from GB888804422A external-priority patent/GB8804422D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IE883820L publication Critical patent/IE883820L/en
Publication of IE61995B1 publication Critical patent/IE61995B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Abstract

AQUEOUS FORMULATIONS CONTAINING A PIPERIDINYLCYCLOPENTYLHEPTENOIC ACID DERIVATIVE Aqueous formulations comprising ¢1R-¢1.alpha.(Z),2.beta.,3.beta.,5.alpha.!!-(+)-7-¢5-¢¢(1,1'-biphenyl)-4-yl!methoxy!-3-hydroxy-2-(1-piperidinyl) cyclopentyl!-4-heptenoic acid or its hydrochloride salt and an unsubstituted or substituted .alpha.-, .beta.- or .gamma.- cyclodextrin have been found which are particularly useful in the treatment or prophylexis of conditions mediated by thromboxene A2. Suitable aqueous formulations include injections, oral preparations such as syrups and capsules and inhalation preparations. [CA1328078C]
IE382088A 1987-12-22 1988-12-21 "Aqueous formulations containing a piperidinylcyclopentylheptenoic acid derivative" IE61995B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878729823A GB8729823D0 (en) 1987-12-22 1987-12-22 Complexes
GB888804422A GB8804422D0 (en) 1988-02-25 1988-02-25 Complexes

Publications (2)

Publication Number Publication Date
IE883820L true IE883820L (en) 1989-06-22
IE61995B1 IE61995B1 (en) 1994-12-14

Family

ID=26293226

Family Applications (1)

Application Number Title Priority Date Filing Date
IE382088A IE61995B1 (en) 1987-12-22 1988-12-21 "Aqueous formulations containing a piperidinylcyclopentylheptenoic acid derivative"

Country Status (29)

Country Link
JP (1) JPH02210A (en)
KR (1) KR890009402A (en)
CN (1) CN1034132A (en)
AT (1) AT395943B (en)
AU (1) AU615245B2 (en)
BE (1) BE1001704A3 (en)
CA (1) CA1328078C (en)
CH (1) CH676665A5 (en)
DE (1) DE3843059A1 (en)
DK (1) DK712888A (en)
ES (1) ES2011727A6 (en)
FI (1) FI885920A (en)
FR (1) FR2624731B1 (en)
GB (1) GB2211737B (en)
GR (1) GR880100854A (en)
HU (1) HU204700B (en)
IE (1) IE61995B1 (en)
IL (1) IL88764A0 (en)
IT (1) IT1224835B (en)
LU (1) LU87411A1 (en)
MY (1) MY103952A (en)
NL (1) NL8803126A (en)
NO (1) NO885689L (en)
NZ (1) NZ227446A (en)
PH (1) PH24982A (en)
PL (1) PL276595A1 (en)
PT (1) PT89301B (en)
SE (1) SE502288C2 (en)
ZW (1) ZW18088A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814725D0 (en) * 1988-06-21 1988-07-27 Glaxo Group Ltd Medicaments
AU616571B2 (en) * 1988-10-28 1991-10-31 Shiseido Company Ltd. Cosmetic composition containing inclusion product with hydroxyalkylated cyclodextrin
IT1269578B (en) * 1994-04-22 1997-04-08 Chiesi Farma Spa MULTI-COMPONENT INCLUSION COMPLEXES WITH HIGH SOLUBILITY CONSISTING OF AN ACID TYPE DRUG, A CYCLODESTRINE AND A BASE.
KR100825736B1 (en) * 2005-12-07 2008-04-29 한국전자통신연구원 Apparatus for providing XML signnature in mobile environment and method thereof
KR100832740B1 (en) * 2007-01-17 2008-05-27 한국과학기술원 Mutant microorganism with improved productivity of branched amino acid and method for preparing it using the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (en) * 1970-06-10 1975-02-04
JPS5443569B2 (en) * 1972-07-05 1979-12-20
HU181703B (en) * 1980-05-09 1983-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing aqueus solutuins of water insoluble or hardly soluble vitamines, steroides, localanesthetics, prostanoides and non-steroid and antiphlogistic agents
JPS57183772A (en) * 1981-04-29 1982-11-12 Glaxo Group Ltd Aminocyclopentanol acids and esters, manufacture and medicinal composition
JPS58116423A (en) * 1981-12-28 1983-07-11 Sumitomo Chem Co Ltd Methanoprostacycline pharmaceutical composition
JPS58192821A (en) * 1982-04-30 1983-11-10 Dainippon Pharmaceut Co Ltd Remedy for anoxia of cranial nerve cells
JPS5946228A (en) * 1982-09-08 1984-03-15 Zeria Shinyaku Kogyo Kk Preparation of water-soluble and lymph-transitional drug containing biologically active organic compound
JPS5973576A (en) * 1982-09-16 1984-04-25 グラクソ・グル−プ・リミテツド Piperidinylcyclopentanolheptanoate
GB2127406B (en) * 1982-09-16 1986-03-05 Glaxo Group Ltd Piperidinlycyclopentanolheptenoic acid salt
DE3346123A1 (en) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse PHARMACEUTICAL PREPARATIONS OF SUBSTANCES MEDICAL OR UNSTABLE IN WATER AND METHOD FOR THE PRODUCTION THEREOF
JPS60150039A (en) * 1984-01-17 1985-08-07 Minolta Camera Co Ltd Amphibious fixed-focus camera
DE3504044A1 (en) * 1985-02-04 1986-08-07 Schering AG, Berlin und Bergkamen, 1000 Berlin 9-HALOGEN PROSTAGLANDIN CLATHRATE AND THEIR USE AS A MEDICINAL PRODUCT
JPS6327440A (en) * 1986-07-18 1988-02-05 Sanraku Inc Glucosylated branched cyclodextrin-containing composition

Also Published As

Publication number Publication date
GR880100854A (en) 1994-03-31
NL8803126A (en) 1989-07-17
CN1034132A (en) 1989-07-26
PL276595A1 (en) 1989-08-21
AU615245B2 (en) 1991-09-26
GB8829793D0 (en) 1989-02-15
DK712888A (en) 1989-06-23
IT8848702A0 (en) 1988-12-21
PT89301A (en) 1990-06-29
GB2211737B (en) 1991-12-11
BE1001704A3 (en) 1990-02-13
HUT50040A (en) 1989-12-28
IL88764A0 (en) 1989-07-31
SE502288C2 (en) 1995-09-25
LU87411A1 (en) 1989-07-07
AT395943B (en) 1993-04-26
FI885920A (en) 1989-06-23
SE8804607D0 (en) 1988-12-21
JPH02210A (en) 1990-01-05
KR890009402A (en) 1989-08-01
PT89301B (en) 1995-07-03
NZ227446A (en) 1991-08-27
ZW18088A1 (en) 1989-07-26
NO885689L (en) 1989-06-23
ES2011727A6 (en) 1990-02-01
MY103952A (en) 1993-10-30
ATA313088A (en) 1992-09-15
IE61995B1 (en) 1994-12-14
AU2735688A (en) 1989-06-22
CH676665A5 (en) 1991-02-28
NO885689D0 (en) 1988-12-21
IT1224835B (en) 1990-10-24
DE3843059A1 (en) 1989-07-13
CA1328078C (en) 1994-03-29
FR2624731A1 (en) 1989-06-23
PH24982A (en) 1990-12-26
SE8804607L (en) 1989-06-23
FR2624731B1 (en) 1992-10-23
GB2211737A (en) 1989-07-12
DK712888D0 (en) 1988-12-21
HU204700B (en) 1992-02-28

Similar Documents

Publication Publication Date Title
AU1819088A (en) New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
IL103746A0 (en) Acetic acid derivatives,their preparation and pharmaceutical compositions containing them
IL104446A0 (en) Acetic acid derivatives,their preparation and pharmaceutical compositions containing them
NZ225361A (en) 9-(substituted benzyl)-tetrahydrocarbazol-1-yl acetic acid derivatives and pharmaceutical compositions
IL84446A0 (en) 3-pyrrolidinylthio-1-azabicyclo-(3.2.0)hept-2-ene-2-carboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL103126A (en) 5-amino-4-hydroxyhexanoic acid derivatives, process for their preparation and pharmaceutical compositions containing them
AU6314790A (en) Oral pharmaceutical composition for acid sensitive proteinaceous agents
AU8202087A (en) 2beta-substituted-methylpenicillanic acid derivatives, and salts and esters thereof
IL105375A0 (en) Acetic acid derivatives,their preparation and pharmaceutical compositions containing them
AU8292687A (en) Thiol-carboxylic acid derivatives
AU8305587A (en) Sialic acid derivatives having active carbonyl group
AU1261788A (en) Amino acid derivatives
AU2330788A (en) Amino acid derivatives
AU587108B2 (en) Imidazolecarboxylic acid derivatives
AU2366088A (en) 2,2-dimethylchromene derivatives, process for their preparation and pharmaceutical compositions in which they are present
IE883820L (en) Piperidinylcyclopentylheptenoic acids compositions
AU599401B2 (en) Amino acid derivatives
IL84808A0 (en) Furanuronic acid derivatives,their preparation and pharmaceutical compositions containing them
NZ224923A (en) 2-methoxymethyl-penem-3-carboxylic acid derivatives and pharmaceutical compositions
HUT49361A (en) Process for producing piperazinecarboxylic acid derivative and pharmaceutical compositions comprising this compound
AU2298288A (en) Amino acid derivatives
AU7317287A (en) 5,6,8-triflouro-quinol-4-one-3-carboxylic acid derivatives
AU1630088A (en) Amino acid derivatives
AU591950B2 (en) Novel 16,17-acetalsubstituted pregnane 21-OIC acid derivatives
IL90244A (en) Peptide-drug compositions, for buccal and nasal administration, containing :-aminoboronic acid derivatives

Legal Events

Date Code Title Description
MM4A Patent lapsed