SE8804607D0 - AQUEOS FORMALATIONS CONTAINING A PIPERIDINYLCYCLOPENTYLHEPTENOIC ACID DERIVATIVE - Google Patents

AQUEOS FORMALATIONS CONTAINING A PIPERIDINYLCYCLOPENTYLHEPTENOIC ACID DERIVATIVE

Info

Publication number
SE8804607D0
SE8804607D0 SE8804607A SE8804607A SE8804607D0 SE 8804607 D0 SE8804607 D0 SE 8804607D0 SE 8804607 A SE8804607 A SE 8804607A SE 8804607 A SE8804607 A SE 8804607A SE 8804607 D0 SE8804607 D0 SE 8804607D0
Authority
SE
Sweden
Prior art keywords
acid derivative
beta
alpha
formalations
aqueos
Prior art date
Application number
SE8804607A
Other languages
Swedish (sv)
Other versions
SE8804607L (en
SE502288C2 (en
Inventor
H Finch
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878729823A external-priority patent/GB8729823D0/en
Priority claimed from GB888804422A external-priority patent/GB8804422D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE8804607D0 publication Critical patent/SE8804607D0/en
Publication of SE8804607L publication Critical patent/SE8804607L/en
Publication of SE502288C2 publication Critical patent/SE502288C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Abstract

AQUEOUS FORMULATIONS CONTAINING A PIPERIDINYLCYCLOPENTYLHEPTENOIC ACID DERIVATIVE Aqueous formulations comprising ¢1R-¢1.alpha.(Z),2.beta.,3.beta.,5.alpha.!!-(+)-7-¢5-¢¢(1,1'-biphenyl)-4-yl!methoxy!-3-hydroxy-2-(1-piperidinyl) cyclopentyl!-4-heptenoic acid or its hydrochloride salt and an unsubstituted or substituted .alpha.-, .beta.- or .gamma.- cyclodextrin have been found which are particularly useful in the treatment or prophylexis of conditions mediated by thromboxene A2. Suitable aqueous formulations include injections, oral preparations such as syrups and capsules and inhalation preparations.
SE8804607A 1987-12-22 1988-12-21 Aqueous composition containing a piperidinylcyclopentylheptenonic acid derivative SE502288C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878729823A GB8729823D0 (en) 1987-12-22 1987-12-22 Complexes
GB888804422A GB8804422D0 (en) 1988-02-25 1988-02-25 Complexes

Publications (3)

Publication Number Publication Date
SE8804607D0 true SE8804607D0 (en) 1988-12-21
SE8804607L SE8804607L (en) 1989-06-23
SE502288C2 SE502288C2 (en) 1995-09-25

Family

ID=26293226

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8804607A SE502288C2 (en) 1987-12-22 1988-12-21 Aqueous composition containing a piperidinylcyclopentylheptenonic acid derivative

Country Status (29)

Country Link
JP (1) JPH02210A (en)
KR (1) KR890009402A (en)
CN (1) CN1034132A (en)
AT (1) AT395943B (en)
AU (1) AU615245B2 (en)
BE (1) BE1001704A3 (en)
CA (1) CA1328078C (en)
CH (1) CH676665A5 (en)
DE (1) DE3843059A1 (en)
DK (1) DK712888A (en)
ES (1) ES2011727A6 (en)
FI (1) FI885920A (en)
FR (1) FR2624731B1 (en)
GB (1) GB2211737B (en)
GR (1) GR880100854A (en)
HU (1) HU204700B (en)
IE (1) IE61995B1 (en)
IL (1) IL88764A0 (en)
IT (1) IT1224835B (en)
LU (1) LU87411A1 (en)
MY (1) MY103952A (en)
NL (1) NL8803126A (en)
NO (1) NO885689L (en)
NZ (1) NZ227446A (en)
PH (1) PH24982A (en)
PL (1) PL276595A1 (en)
PT (1) PT89301B (en)
SE (1) SE502288C2 (en)
ZW (1) ZW18088A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814725D0 (en) * 1988-06-21 1988-07-27 Glaxo Group Ltd Medicaments
AU616571B2 (en) * 1988-10-28 1991-10-31 Shiseido Company Ltd. Cosmetic composition containing inclusion product with hydroxyalkylated cyclodextrin
IT1269578B (en) * 1994-04-22 1997-04-08 Chiesi Farma Spa MULTI-COMPONENT INCLUSION COMPLEXES WITH HIGH SOLUBILITY CONSISTING OF AN ACID TYPE DRUG, A CYCLODESTRINE AND A BASE.
KR100825736B1 (en) * 2005-12-07 2008-04-29 한국전자통신연구원 Apparatus for providing XML signnature in mobile environment and method thereof
KR100832740B1 (en) * 2007-01-17 2008-05-27 한국과학기술원 Mutant microorganism with improved productivity of branched amino acid and method for preparing it using the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (en) * 1970-06-10 1975-02-04
JPS5443569B2 (en) * 1972-07-05 1979-12-20
HU181703B (en) * 1980-05-09 1983-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing aqueus solutuins of water insoluble or hardly soluble vitamines, steroides, localanesthetics, prostanoides and non-steroid and antiphlogistic agents
JPS57183772A (en) * 1981-04-29 1982-11-12 Glaxo Group Ltd Aminocyclopentanol acids and esters, manufacture and medicinal composition
JPS58116423A (en) * 1981-12-28 1983-07-11 Sumitomo Chem Co Ltd Methanoprostacycline pharmaceutical composition
JPS58192821A (en) * 1982-04-30 1983-11-10 Dainippon Pharmaceut Co Ltd Remedy for anoxia of cranial nerve cells
JPS5946228A (en) * 1982-09-08 1984-03-15 Zeria Shinyaku Kogyo Kk Preparation of water-soluble and lymph-transitional drug containing biologically active organic compound
JPS5973576A (en) * 1982-09-16 1984-04-25 グラクソ・グル−プ・リミテツド Piperidinylcyclopentanolheptanoate
GB2127406B (en) * 1982-09-16 1986-03-05 Glaxo Group Ltd Piperidinlycyclopentanolheptenoic acid salt
DE3346123A1 (en) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse PHARMACEUTICAL PREPARATIONS OF SUBSTANCES MEDICAL OR UNSTABLE IN WATER AND METHOD FOR THE PRODUCTION THEREOF
JPS60150039A (en) * 1984-01-17 1985-08-07 Minolta Camera Co Ltd Amphibious fixed-focus camera
DE3504044A1 (en) * 1985-02-04 1986-08-07 Schering AG, Berlin und Bergkamen, 1000 Berlin 9-HALOGEN PROSTAGLANDIN CLATHRATE AND THEIR USE AS A MEDICINAL PRODUCT
JPS6327440A (en) * 1986-07-18 1988-02-05 Sanraku Inc Glucosylated branched cyclodextrin-containing composition

Also Published As

Publication number Publication date
NZ227446A (en) 1991-08-27
FI885920A (en) 1989-06-23
DK712888D0 (en) 1988-12-21
AU615245B2 (en) 1991-09-26
ATA313088A (en) 1992-09-15
DK712888A (en) 1989-06-23
BE1001704A3 (en) 1990-02-13
CA1328078C (en) 1994-03-29
PH24982A (en) 1990-12-26
FR2624731A1 (en) 1989-06-23
PT89301A (en) 1990-06-29
GB2211737B (en) 1991-12-11
SE8804607L (en) 1989-06-23
GR880100854A (en) 1994-03-31
CH676665A5 (en) 1991-02-28
CN1034132A (en) 1989-07-26
PL276595A1 (en) 1989-08-21
HUT50040A (en) 1989-12-28
SE502288C2 (en) 1995-09-25
MY103952A (en) 1993-10-30
ES2011727A6 (en) 1990-02-01
FR2624731B1 (en) 1992-10-23
ZW18088A1 (en) 1989-07-26
NO885689L (en) 1989-06-23
AT395943B (en) 1993-04-26
LU87411A1 (en) 1989-07-07
JPH02210A (en) 1990-01-05
KR890009402A (en) 1989-08-01
IT1224835B (en) 1990-10-24
GB8829793D0 (en) 1989-02-15
HU204700B (en) 1992-02-28
NO885689D0 (en) 1988-12-21
DE3843059A1 (en) 1989-07-13
IT8848702A0 (en) 1988-12-21
AU2735688A (en) 1989-06-22
IE61995B1 (en) 1994-12-14
NL8803126A (en) 1989-07-17
IL88764A0 (en) 1989-07-31
IE883820L (en) 1989-06-22
GB2211737A (en) 1989-07-12
PT89301B (en) 1995-07-03

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