GB2196634B - Monoclonal antibodies to hiv and related peptides - Google Patents

Monoclonal antibodies to hiv and related peptides

Info

Publication number
GB2196634B
GB2196634B GB8719587A GB8719587A GB2196634B GB 2196634 B GB2196634 B GB 2196634B GB 8719587 A GB8719587 A GB 8719587A GB 8719587 A GB8719587 A GB 8719587A GB 2196634 B GB2196634 B GB 2196634B
Authority
GB
United Kingdom
Prior art keywords
hiv
monoclonal antibodies
related peptides
peptides
monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8719587A
Other languages
English (en)
Other versions
GB2196634A (en
GB8719587D0 (en
Inventor
Mary Kathleen Shriver
Elaine K Thomas
Wesley L Cosand
Larry H Gosting
Edna S Dickinson
Janela
George J Todaro
Robert C Nowinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetic Systems Corp
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of GB8719587D0 publication Critical patent/GB8719587D0/en
Publication of GB2196634A publication Critical patent/GB2196634A/en
Application granted granted Critical
Publication of GB2196634B publication Critical patent/GB2196634B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00Multi-stage pumps
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • AIDS & HIV (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB8719587A 1986-08-20 1987-08-19 Monoclonal antibodies to hiv and related peptides Expired - Fee Related GB2196634B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (3)

Publication Number Publication Date
GB8719587D0 GB8719587D0 (en) 1987-09-23
GB2196634A GB2196634A (en) 1988-05-05
GB2196634B true GB2196634B (en) 1991-05-15

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8719587A Expired - Fee Related GB2196634B (en) 1986-08-20 1987-08-19 Monoclonal antibodies to hiv and related peptides

Country Status (28)

Country Link
JP (1) JPS6485928A (da)
KR (1) KR920008744B1 (da)
AT (1) AT398080B (da)
AU (1) AU616156B2 (da)
BE (1) BE1000811A4 (da)
CH (1) CH675728A5 (da)
CS (1) CS275838B6 (da)
DE (1) DE3727703A1 (da)
DK (1) DK433087A (da)
ES (1) ES2010727A6 (da)
FI (1) FI873553A (da)
FR (1) FR2603107B1 (da)
GB (1) GB2196634B (da)
GR (1) GR871298B (da)
HU (1) HU214439B (da)
IE (1) IE60671B1 (da)
IL (1) IL83580A (da)
IT (1) IT1222518B (da)
LU (1) LU86972A1 (da)
NL (1) NL8701950A (da)
NO (2) NO300462B1 (da)
NZ (1) NZ221440A (da)
OA (1) OA08652A (da)
PL (1) PL155084B1 (da)
PT (1) PT85567B (da)
SE (1) SE506025C2 (da)
YU (1) YU152587A (da)
ZW (1) ZW15487A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
EP0366718B1 (en) * 1987-05-29 1995-05-10 Tanox Biosystems, Inc. Monoclonal antibodies neutralizing hiv-1
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
ATE138077T1 (de) * 1988-01-26 1996-06-15 Us Health Synthetisches antigen zum bewirken einer anti-hiv-reaktion
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (fr) * 1988-06-06 1992-04-10 Pasteur Institut Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles
AU640619B2 (en) * 1988-10-03 1993-09-02 Repligen Corporation Hiv proteins and peptides useful in the diagnosis, prophylaxis or therapy of aids
EP0421626A1 (en) * 1989-09-19 1991-04-10 Merck & Co. Inc. Vaccine for aids and hepatitis B
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv関連環状ペプチドおよびこれを固定化した吸着体
DK0635027T3 (da) * 1992-03-27 2000-10-02 Advanced Immunit T Inc Peptid T og beslægtede peptider til behandling af inflammation, herunder dissemineret sclerose
KR20140041943A (ko) 2005-12-09 2014-04-04 벡투스 바이오시스템즈 피티와이 리미티드 Vip 단편 및 사용 방법
US8253311B2 (en) 2008-09-02 2012-08-28 Ngk Spark Plug Co., Ltd Spark plug

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986002383A1 (en) * 1984-10-18 1986-04-24 Institut Pasteur Envelope antigens of lymphadenopathy associated virus and their applications
EP0185444A2 (en) * 1984-10-10 1986-06-25 Centocor, Inc. Cloning and expression of HTLV-III DNA
WO1986004336A1 (en) * 1985-01-21 1986-07-31 Institut Pasteur Monoclonal antibodies against core proteins of lymphadenopathy-associated-viruses
EP0219106A2 (en) * 1985-10-17 1987-04-22 F. Hoffmann-La Roche Ag Polypeptides that elicit antibodies against AIDS virus
WO1987002988A1 (en) * 1985-11-07 1987-05-21 President And Fellows Of Harvard College T-cell lymphotrophic virus protein and assay
EP0231914A2 (en) * 1986-02-03 1987-08-12 F. Hoffmann-La Roche Ag HTLV-III envelope peptides
GB2188639A (en) * 1986-04-04 1987-10-07 Hoffmann La Roche Expression and purification of an HTLV-111 GAG/ENV gene protein
EP0251612A2 (en) * 1986-06-23 1988-01-07 Bristol-Myers Squibb Company Human monoclonal antibody to lymphadenopathy-associated virus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
ES8706824A1 (es) * 1985-04-08 1987-07-01 Genetic Systems Corp Un metodo para preparar proteinas que son inmunologicamente reactivas con anticuerpos para virus asociados con linfadenopatia.
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
NZ215867A (en) * 1985-04-19 1989-10-27 Hoffmann La Roche Aids envelope protein, dna vectors and method of production
WO1986006414A1 (en) * 1985-04-29 1986-11-06 Genetic Systems Corporation Synthetic antigens for the detection of aids-related disease
EP0245362B1 (en) * 1985-10-24 1994-06-29 Ronald C. Kennedy Synthetic peptides and use for diagnosis and vaccination for aids and arc
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
EP0255190A3 (en) * 1986-08-01 1990-08-29 Repligen Corporation Recombinant polypeptides and their uses, inclusing assay for aids virus
JPH0762031B2 (ja) * 1986-12-30 1995-07-05 アメリカ合衆国 エイズウイルスおよびエイズウイルスのタンパク質に対する細胞性免疫を誘導する合成ペプチド

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0185444A2 (en) * 1984-10-10 1986-06-25 Centocor, Inc. Cloning and expression of HTLV-III DNA
WO1986002383A1 (en) * 1984-10-18 1986-04-24 Institut Pasteur Envelope antigens of lymphadenopathy associated virus and their applications
WO1986004336A1 (en) * 1985-01-21 1986-07-31 Institut Pasteur Monoclonal antibodies against core proteins of lymphadenopathy-associated-viruses
EP0219106A2 (en) * 1985-10-17 1987-04-22 F. Hoffmann-La Roche Ag Polypeptides that elicit antibodies against AIDS virus
WO1987002988A1 (en) * 1985-11-07 1987-05-21 President And Fellows Of Harvard College T-cell lymphotrophic virus protein and assay
EP0231914A2 (en) * 1986-02-03 1987-08-12 F. Hoffmann-La Roche Ag HTLV-III envelope peptides
GB2188639A (en) * 1986-04-04 1987-10-07 Hoffmann La Roche Expression and purification of an HTLV-111 GAG/ENV gene protein
EP0251612A2 (en) * 1986-06-23 1988-01-07 Bristol-Myers Squibb Company Human monoclonal antibody to lymphadenopathy-associated virus

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
J.Cellular Biochem.Supp. Vol.0 No.9 part A (1985) p92 *
J.Clin.Microbiology Vol.25 No.5 (1987) pp845-848 *
J.Gen.Virology Vol.68 No.6 (1987) pp1543-1552 *
J.Immunology Vol.136 No.4 (1986) pp1442-1445 *
Proc.Natl.Acad.Sci. (USA) Vol.82 (1985) pp5199-5202 *

Also Published As

Publication number Publication date
NO934897D0 (no) 1993-12-29
SE506025C2 (sv) 1997-11-03
AU616156B2 (en) 1991-10-24
DK433087A (da) 1988-02-21
FI873553A (fi) 1988-02-21
KR890002547A (ko) 1989-04-10
IE60671B1 (en) 1994-08-10
FR2603107B1 (fr) 1992-04-24
ZW15487A1 (en) 1988-09-14
PL267401A1 (en) 1988-07-21
NZ221440A (en) 1991-11-26
GB2196634A (en) 1988-05-05
ATA208987A (de) 1994-01-15
KR920008744B1 (ko) 1992-10-09
IL83580A (en) 1992-11-15
NO873495L (no) 1988-02-22
SE8703225L (sv) 1988-02-21
ES2010727A6 (es) 1989-12-01
NL8701950A (nl) 1988-03-16
PT85567B (pt) 1991-02-08
GB8719587D0 (en) 1987-09-23
IE872219L (en) 1988-02-20
IT8721678A0 (it) 1987-08-19
CS275838B6 (en) 1992-03-18
PL155084B1 (en) 1991-10-31
GR871298B (en) 1988-01-12
CH675728A5 (da) 1990-10-31
DE3727703A1 (de) 1988-05-05
NO300462B1 (no) 1997-06-02
NO873495D0 (no) 1987-08-19
JPS6485928A (en) 1989-03-30
BE1000811A4 (fr) 1989-04-11
HUT44619A (en) 1988-03-28
AT398080B (de) 1994-09-26
YU152587A (sh) 1992-09-07
IT1222518B (it) 1990-09-05
FR2603107A1 (fr) 1988-02-26
LU86972A1 (fr) 1988-03-02
OA08652A (fr) 1988-11-30
NO302176B1 (no) 1998-02-02
HU214439B (hu) 1998-03-30
CS8706136A2 (en) 1990-08-14
NO934897L (no) 1993-12-29
PT85567A (en) 1987-09-01
FI873553A0 (fi) 1987-08-17
AU7720187A (en) 1988-05-19
IL83580A0 (en) 1988-01-31
SE8703225D0 (sv) 1987-08-19
DK433087D0 (da) 1987-08-19

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19980819