GB2162518B - Fluoroallylamine derivatives - Google Patents

Fluoroallylamine derivatives

Info

Publication number
GB2162518B
GB2162518B GB08517454A GB8517454A GB2162518B GB 2162518 B GB2162518 B GB 2162518B GB 08517454 A GB08517454 A GB 08517454A GB 8517454 A GB8517454 A GB 8517454A GB 2162518 B GB2162518 B GB 2162518B
Authority
GB
United Kingdom
Prior art keywords
fluoroallylamine derivatives
fluoroallylamine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08517454A
Other languages
English (en)
Other versions
GB8517454D0 (en
GB2162518A (en
Inventor
Ian Alexander Mcdonald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of GB8517454D0 publication Critical patent/GB8517454D0/en
Publication of GB2162518A publication Critical patent/GB2162518A/en
Application granted granted Critical
Publication of GB2162518B publication Critical patent/GB2162518B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40Halogenated unsaturated alcohols
    • C07C33/42Halogenated unsaturated alcohols acyclic
    • C07C33/423Halogenated unsaturated alcohols acyclic containing only double bonds as unsaturation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GB08517454A 1984-07-13 1985-07-10 Fluoroallylamine derivatives Expired GB2162518B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63055684A 1984-07-13 1984-07-13

Publications (3)

Publication Number Publication Date
GB8517454D0 GB8517454D0 (en) 1985-08-14
GB2162518A GB2162518A (en) 1986-02-05
GB2162518B true GB2162518B (en) 1987-11-18

Family

ID=24527644

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08517454A Expired GB2162518B (en) 1984-07-13 1985-07-10 Fluoroallylamine derivatives

Country Status (20)

Country Link
EP (1) EP0168013B1 (https=)
JP (1) JPS61257952A (https=)
KR (1) KR900008113B1 (https=)
AR (1) AR240043A1 (https=)
AT (1) ATE32711T1 (https=)
AU (1) AU575973B2 (https=)
CA (1) CA1256453A (https=)
DE (1) DE3561723D1 (https=)
DK (1) DK166878C (https=)
ES (1) ES545111A0 (https=)
FI (1) FI84057C (https=)
GB (1) GB2162518B (https=)
HU (1) HU195181B (https=)
IE (1) IE58305B1 (https=)
IL (1) IL75739A (https=)
NO (1) NO161313C (https=)
NZ (1) NZ212675A (https=)
PH (1) PH21647A (https=)
PT (1) PT80805B (https=)
ZA (1) ZA855101B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3683604D1 (de) * 1985-12-05 1992-03-05 Merrell Dow Pharma Nichtaromatische fluoralkylamin-mao-inhibitoren.
EP0283168A3 (en) * 1987-03-16 1989-06-14 American Home Products Corporation Fluorooxirane carboxylates
US4822812A (en) * 1987-05-21 1989-04-18 Merrell Dow Pharmaceuticals Inc. β-(Fluoromethylene)-5-hydroxytryptophan and derivatives and their use as prodrugs for MAO inhibition
US5059714A (en) * 1988-02-25 1991-10-22 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5252608A (en) * 1988-02-25 1993-10-12 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US4965288A (en) * 1988-02-25 1990-10-23 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5488188A (en) * 1994-09-29 1996-01-30 Merrell Dow Pharmaceuticals Inc. Process for the preparation of (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, novel processes for preparing an intermediate thereof, and novel intermediates thereof
US20070293548A1 (en) * 2006-03-31 2007-12-20 Wang Eric Y Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment and prevention of diseases
AU2013255103B2 (en) 2012-05-02 2016-09-29 Syntara Limited Substituted 3-haloallylamine inhibitors of SSAO and uses thereof
AU2023331414A1 (en) * 2022-08-29 2025-03-27 Syntara Limited Novel selective inhibitors of lysyl oxidases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1027611A (en) * 1962-01-04 1966-04-27 May & Baker Ltd Phenoxy- and phenylthio-alkylamines and acid addition salts thereof
US3205136A (en) * 1962-12-24 1965-09-07 Smith Kline French Lab Antidepressant phenyloxyalkylamines
US3513198A (en) * 1965-10-22 1970-05-19 Hoffmann La Roche Aryloxy- and arylthio-acetylenic amines and the salts thereof
CH485681A (de) * 1966-06-03 1970-02-15 Ciba Geigy Verfahren zur Herstellung von schwefelhaltigen Aminen

Also Published As

Publication number Publication date
ATE32711T1 (de) 1988-03-15
NZ212675A (en) 1988-02-29
FI84057C (fi) 1991-10-10
DK166878C (da) 1993-12-13
IL75739A0 (en) 1985-11-29
ES8603809A1 (es) 1986-01-01
GB8517454D0 (en) 1985-08-14
PT80805B (pt) 1987-09-18
KR900008113B1 (ko) 1990-10-31
FI852748L (fi) 1986-01-14
ES545111A0 (es) 1986-01-01
FI84057B (fi) 1991-06-28
CA1256453A (en) 1989-06-27
AR240043A1 (es) 1990-01-31
DK320585A (da) 1986-01-14
JPH0530823B2 (https=) 1993-05-11
DK166878B (da) 1993-07-26
EP0168013B1 (en) 1988-03-02
IE58305B1 (en) 1993-09-08
PH21647A (en) 1988-01-13
JPS61257952A (ja) 1986-11-15
KR860001048A (ko) 1986-02-22
IE851746L (en) 1986-01-13
NO852810L (no) 1986-01-14
AU4466085A (en) 1986-01-16
AU575973B2 (en) 1988-08-11
IL75739A (en) 1988-07-31
ZA855101B (en) 1986-05-28
FI852748A0 (fi) 1985-07-11
EP0168013A1 (en) 1986-01-15
DK320585D0 (da) 1985-07-12
GB2162518A (en) 1986-02-05
NO161313C (no) 1989-08-02
PT80805A (en) 1985-08-01
DE3561723D1 (de) 1988-04-07
HU195181B (en) 1988-04-28
HUT38604A (en) 1986-06-30
NO161313B (no) 1989-04-24

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20000710