DE3561723D1 - Fluoroallylamine derivatives - Google Patents

Fluoroallylamine derivatives

Info

Publication number
DE3561723D1
DE3561723D1 DE8585108443T DE3561723T DE3561723D1 DE 3561723 D1 DE3561723 D1 DE 3561723D1 DE 8585108443 T DE8585108443 T DE 8585108443T DE 3561723 T DE3561723 T DE 3561723T DE 3561723 D1 DE3561723 D1 DE 3561723D1
Authority
DE
Germany
Prior art keywords
fluoroallylamine derivatives
fluoroallylamine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585108443T
Other languages
German (de)
English (en)
Inventor
Ian Alexander Mcdonald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE3561723D1 publication Critical patent/DE3561723D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/42—Halogenated unsaturated alcohols acyclic
    • C07C33/423—Halogenated unsaturated alcohols acyclic containing only double bonds as unsaturation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE8585108443T 1984-07-13 1985-07-08 Fluoroallylamine derivatives Expired DE3561723D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63055684A 1984-07-13 1984-07-13

Publications (1)

Publication Number Publication Date
DE3561723D1 true DE3561723D1 (de) 1988-04-07

Family

ID=24527644

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585108443T Expired DE3561723D1 (de) 1984-07-13 1985-07-08 Fluoroallylamine derivatives

Country Status (20)

Country Link
EP (1) EP0168013B1 (https=)
JP (1) JPS61257952A (https=)
KR (1) KR900008113B1 (https=)
AR (1) AR240043A1 (https=)
AT (1) ATE32711T1 (https=)
AU (1) AU575973B2 (https=)
CA (1) CA1256453A (https=)
DE (1) DE3561723D1 (https=)
DK (1) DK166878C (https=)
ES (1) ES545111A0 (https=)
FI (1) FI84057C (https=)
GB (1) GB2162518B (https=)
HU (1) HU195181B (https=)
IE (1) IE58305B1 (https=)
IL (1) IL75739A (https=)
NO (1) NO161313C (https=)
NZ (1) NZ212675A (https=)
PH (1) PH21647A (https=)
PT (1) PT80805B (https=)
ZA (1) ZA855101B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3683604D1 (de) * 1985-12-05 1992-03-05 Merrell Dow Pharma Nichtaromatische fluoralkylamin-mao-inhibitoren.
EP0283168A3 (en) * 1987-03-16 1989-06-14 American Home Products Corporation Fluorooxirane carboxylates
US4822812A (en) * 1987-05-21 1989-04-18 Merrell Dow Pharmaceuticals Inc. β-(Fluoromethylene)-5-hydroxytryptophan and derivatives and their use as prodrugs for MAO inhibition
US5059714A (en) * 1988-02-25 1991-10-22 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5252608A (en) * 1988-02-25 1993-10-12 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US4965288A (en) * 1988-02-25 1990-10-23 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5488188A (en) * 1994-09-29 1996-01-30 Merrell Dow Pharmaceuticals Inc. Process for the preparation of (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, novel processes for preparing an intermediate thereof, and novel intermediates thereof
US20070293548A1 (en) * 2006-03-31 2007-12-20 Wang Eric Y Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment and prevention of diseases
AU2013255103B2 (en) 2012-05-02 2016-09-29 Syntara Limited Substituted 3-haloallylamine inhibitors of SSAO and uses thereof
AU2023331414A1 (en) * 2022-08-29 2025-03-27 Syntara Limited Novel selective inhibitors of lysyl oxidases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1027611A (en) * 1962-01-04 1966-04-27 May & Baker Ltd Phenoxy- and phenylthio-alkylamines and acid addition salts thereof
US3205136A (en) * 1962-12-24 1965-09-07 Smith Kline French Lab Antidepressant phenyloxyalkylamines
US3513198A (en) * 1965-10-22 1970-05-19 Hoffmann La Roche Aryloxy- and arylthio-acetylenic amines and the salts thereof
CH485681A (de) * 1966-06-03 1970-02-15 Ciba Geigy Verfahren zur Herstellung von schwefelhaltigen Aminen

Also Published As

Publication number Publication date
ATE32711T1 (de) 1988-03-15
NZ212675A (en) 1988-02-29
FI84057C (fi) 1991-10-10
DK166878C (da) 1993-12-13
IL75739A0 (en) 1985-11-29
ES8603809A1 (es) 1986-01-01
GB8517454D0 (en) 1985-08-14
PT80805B (pt) 1987-09-18
KR900008113B1 (ko) 1990-10-31
FI852748L (fi) 1986-01-14
ES545111A0 (es) 1986-01-01
FI84057B (fi) 1991-06-28
CA1256453A (en) 1989-06-27
GB2162518B (en) 1987-11-18
AR240043A1 (es) 1990-01-31
DK320585A (da) 1986-01-14
JPH0530823B2 (https=) 1993-05-11
DK166878B (da) 1993-07-26
EP0168013B1 (en) 1988-03-02
IE58305B1 (en) 1993-09-08
PH21647A (en) 1988-01-13
JPS61257952A (ja) 1986-11-15
KR860001048A (ko) 1986-02-22
IE851746L (en) 1986-01-13
NO852810L (no) 1986-01-14
AU4466085A (en) 1986-01-16
AU575973B2 (en) 1988-08-11
IL75739A (en) 1988-07-31
ZA855101B (en) 1986-05-28
FI852748A0 (fi) 1985-07-11
EP0168013A1 (en) 1986-01-15
DK320585D0 (da) 1985-07-12
GB2162518A (en) 1986-02-05
NO161313C (no) 1989-08-02
PT80805A (en) 1985-08-01
HU195181B (en) 1988-04-28
HUT38604A (en) 1986-06-30
NO161313B (no) 1989-04-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee