GB2056982B - 2 - phenylimidazo(2,1 - b)benzothiazole derivatives - Google Patents

2 - phenylimidazo(2,1 - b)benzothiazole derivatives

Info

Publication number
GB2056982B
GB2056982B GB8027243A GB8027243A GB2056982B GB 2056982 B GB2056982 B GB 2056982B GB 8027243 A GB8027243 A GB 8027243A GB 8027243 A GB8027243 A GB 8027243A GB 2056982 B GB2056982 B GB 2056982B
Authority
GB
United Kingdom
Prior art keywords
phenylimidazo
benzothiazole derivatives
benzothiazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8027243A
Other languages
English (en)
Other versions
GB2056982A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10643879A external-priority patent/JPS5630990A/ja
Priority claimed from JP14507779A external-priority patent/JPS5668685A/ja
Priority claimed from JP14844179A external-priority patent/JPS5671096A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of GB2056982A publication Critical patent/GB2056982A/en
Application granted granted Critical
Publication of GB2056982B publication Critical patent/GB2056982B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GB8027243A 1979-08-21 1980-08-21 2 - phenylimidazo(2,1 - b)benzothiazole derivatives Expired GB2056982B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10643879A JPS5630990A (en) 1979-08-21 1979-08-21 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation
JP14507779A JPS5668685A (en) 1979-11-09 1979-11-09 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation
JP14844179A JPS5671096A (en) 1979-11-16 1979-11-16 2-phenylimidazo 2,1-b- benzothiazole derivative

Publications (2)

Publication Number Publication Date
GB2056982A GB2056982A (en) 1981-03-25
GB2056982B true GB2056982B (en) 1983-11-16

Family

ID=27310731

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8027243A Expired GB2056982B (en) 1979-08-21 1980-08-21 2 - phenylimidazo(2,1 - b)benzothiazole derivatives

Country Status (8)

Country Link
US (1) US4497817A (enExample)
AT (1) ATA425280A (enExample)
CA (1) CA1158246A (enExample)
DE (1) DE3030982A1 (enExample)
ES (1) ES8106535A1 (enExample)
FR (1) FR2463774A1 (enExample)
GB (1) GB2056982B (enExample)
IT (1) IT1166483B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464384A (en) * 1981-12-23 1984-08-07 Yamanouchi Pharmaceutical Co., Ltd. 2-Phenylimidazo[2,1-b]benzothiazole compounds, salts thereof, process of producing them, and pharmaceutical compositions containing them
JP2726999B2 (ja) * 1988-06-22 1998-03-11 日研化学株式会社 イミダゾ［２，１−ｂ］ベンゾチアゾール誘導体及び該化合物を有効成分とする抗潰瘍剤
IT1243362B (it) * 1990-07-25 1994-06-10 Pietro Monforte Sintesi di attivita' anti-hiv di 1h, 3h-tiazolo 3,4-a benzimidazoli 1-sostituiti
WO1996028454A1 (en) * 1995-03-13 1996-09-19 Nikken Chemicals Co., Ltd. Imidazothiazole compounds
WO1998006724A1 (en) * 1996-08-09 1998-02-19 Yamanouchi Pharmaceutical Co., Ltd. Metabotropic glutamate receptor agonists
US6127387A (en) * 1996-12-10 2000-10-03 Thomas Jefferson University Use of CD4-binding small molecules to inhibit immune responses
WO2000044364A2 (en) * 1999-01-29 2000-08-03 The Board Of Trustees Of The University Of Illinois P53 inhibitors and their use for the treatment of cancer, hyperthermia, hypoxia, a burn, trauma to the central nervous system, a seizure, acute inflammation, tissue ageing, preservation of organs for transplant and preparation of a host for bone marrow transplant
DE19948434A1 (de) * 1999-10-08 2001-06-07 Gruenenthal Gmbh Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
DE19948436B4 (de) * 1999-10-08 2006-11-16 Grünenthal GmbH Bicyclische Imidazo-5-aminderivate
US6867299B2 (en) 2000-02-24 2005-03-15 Hoffmann-La Roche Inc. Oxamide IMPDH inhibitors
US7601846B2 (en) * 2001-06-26 2009-10-13 The Regents Of The University Of California Compounds having activity as inhibitors of apoptosis
DE10150172A1 (de) * 2001-10-11 2003-04-30 Morphochem Ag Neue Verbindungen, die Protein Tyrosin Phosphatase 1B (PTP-1B) inhibieren
JP4991547B2 (ja) * 2004-09-28 2012-08-01 クアーク・ファーマスーティカルス、インコーポレイテッド 脱毛症、急性腎不全および他の疾患の治療のためのオリゴリボヌクレオチドおよびその使用の方法
US7825099B2 (en) * 2006-01-20 2010-11-02 Quark Pharmaceuticals, Inc. Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
US7910566B2 (en) * 2006-03-09 2011-03-22 Quark Pharmaceuticals Inc. Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA
TWI409267B (zh) * 2006-03-17 2013-09-21 Ambit Biosciences Corp 治療疾病用之咪唑并噻唑化合物
WO2009001359A2 (en) * 2007-06-27 2008-12-31 Quark Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of pro-apoptotic genes
KR101572701B1 (ko) * 2007-09-19 2015-11-27 암비트 바이오사이언시즈 코포레이션 Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ'-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도
EP2218464A1 (en) * 2009-02-11 2010-08-18 Technische Universität München Compounds for non-invasive measurement of aggregates of amyloid peptides
CN107417705B (zh) * 2017-07-24 2019-07-02 湘潭大学 咪唑并[2,1-b]苯并噻唑类化合物及其合成方法
IL279972A (en) * 2021-01-05 2022-08-01 Anima Biotech Inc Substances that function as modulators of cmyc-mrna translation and their uses in cancer treatment
EP4547671A1 (en) * 2022-07-03 2025-05-07 Anima Biotech Inc. C-myc mrna translation modulators and uses thereof in the treatment of cancer
US12404283B2 (en) 2022-07-03 2025-09-02 Anima Biotech Inc. c-MYC mRNA translation modulators and uses thereof in the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129432C (enExample) * 1964-02-29
US4080339A (en) * 1973-09-20 1978-03-21 Pfizer Inc. Imidazo[2,1-b]thiazole and thiazolo[3,2-a]benzimidazole quaternary salts as hypoglycemic agents and growth promotants
GB1541321A (en) * 1976-03-10 1979-02-28 Metabio 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation
US4262004A (en) * 1979-06-21 1981-04-14 Janssen Pharmaceutica, N.V. 2,3-Dihydro-imidazo[2,1-b]benzothiazole compositions to treat depressions

Also Published As

Publication number Publication date
US4497817A (en) 1985-02-05
CA1158246A (en) 1983-12-06
DE3030982A1 (de) 1981-03-12
IT8068303A0 (it) 1980-08-20
FR2463774B1 (enExample) 1983-10-21
ATA425280A (de) 1986-01-15
IT1166483B (it) 1987-05-06
FR2463774A1 (fr) 1981-02-27
GB2056982A (en) 1981-03-25
ES494397A0 (es) 1981-08-01
ES8106535A1 (es) 1981-08-01

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee