JPS5668685A - 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation - Google Patents
2-phenylimidazo 2,1-b benzothiazole derivative and its preparationInfo
- Publication number
- JPS5668685A JPS5668685A JP14507779A JP14507779A JPS5668685A JP S5668685 A JPS5668685 A JP S5668685A JP 14507779 A JP14507779 A JP 14507779A JP 14507779 A JP14507779 A JP 14507779A JP S5668685 A JPS5668685 A JP S5668685A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- halogen
- compound
- lower alkyl
- phenylimidazo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The titled compound formula I (R1, R2 and R3 are H, halogen, lower alkyl, OH, etc.; R4 is halogen, lower alkyl, lower alkoxyl, etc.; R5 is H, halogen, lower alkyl, etc.; X is H, halogen, nitroso, etc.; the dotted line is the presence or absence of a double bond) and a salt thereof.
EXAMPLE: 2-(m-Hydroxyphenyl)-7-methylimidazo[2,1-b]benzothiazole.
USE: An antiallergic, antiasthmatic, antirheumatic, anti-inflammatory, and carcinostatic agents and a remedy for autoimmune diseases. The derivative has a regulating action on the immune function.
PROCESS: A compound of formula II [A is carbonyl or group of formula III (Y is halogen)] is cyclized in a solvent, e.g. methanol, under heating to give the compound of formula I. Most of the compounds of formula II are novel substances and obtained by reacting a compound of formula IV with a compound of formula V.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14507779A JPS5668685A (en) | 1979-11-09 | 1979-11-09 | 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation |
FR8017896A FR2463774A1 (en) | 1979-08-21 | 1980-08-13 | DERIVATIVES OF 2-PHENYLIMIDAZO (2,1-B) BENZOTHIAZOLE |
DE19803030982 DE3030982A1 (en) | 1979-08-21 | 1980-08-16 | 2-PHENYLIMIDAZO (2,1-B) BENZOTHIAZOLE DERIVATIVES |
AT0425280A ATA425280A (en) | 1979-08-21 | 1980-08-20 | METHOD FOR PRODUCING NEW 2-PHENYL-IMIDAZO (2.1-B) -BENZOTHIAZOLE DERIVATIVES |
IT68303/80A IT1166483B (en) | 1979-08-21 | 1980-08-20 | DERIVATIVES OF 2 FENYLIMIDAZO 2 1 B BENZOTHIAZOLE HAVING AN IMMUNOREGULATORY EFFECT AND PROCEDURE FOR THEIR PREPARATION |
ES494397A ES494397A0 (en) | 1979-08-21 | 1980-08-20 | A PRODUCTION PROCEDURE OF A 2-PHENYLIMI-DAZO (2,1-B) BENZOTIAZOLE DERIVATIVE |
CA000358790A CA1158246A (en) | 1979-08-21 | 1980-08-21 | Process of producing 2-phenylimidazo¬2,1-b| benzothiazole derivatives |
GB8027243A GB2056982B (en) | 1979-08-21 | 1980-08-21 | 2 - phenylimidazo(2,1 - b)benzothiazole derivatives |
US06/487,357 US4497817A (en) | 1979-08-21 | 1983-04-26 | 2-Phenylimidazo [2,1-b]benzothiazole derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14507779A JPS5668685A (en) | 1979-11-09 | 1979-11-09 | 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5668685A true JPS5668685A (en) | 1981-06-09 |
JPS6320236B2 JPS6320236B2 (en) | 1988-04-26 |
Family
ID=15376841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14507779A Granted JPS5668685A (en) | 1979-08-21 | 1979-11-09 | 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5668685A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4968708A (en) * | 1988-06-22 | 1990-11-06 | Nikken Chemicals Co., Ltd. | Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same |
JP2007112513A (en) * | 2005-09-22 | 2007-05-10 | Nippon Paper-Pak Co Ltd | Article supporting member |
-
1979
- 1979-11-09 JP JP14507779A patent/JPS5668685A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4968708A (en) * | 1988-06-22 | 1990-11-06 | Nikken Chemicals Co., Ltd. | Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same |
JP2007112513A (en) * | 2005-09-22 | 2007-05-10 | Nippon Paper-Pak Co Ltd | Article supporting member |
Also Published As
Publication number | Publication date |
---|---|
JPS6320236B2 (en) | 1988-04-26 |
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