JPS5668685A - 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation - Google Patents

2-phenylimidazo 2,1-b benzothiazole derivative and its preparation

Info

Publication number
JPS5668685A
JPS5668685A JP14507779A JP14507779A JPS5668685A JP S5668685 A JPS5668685 A JP S5668685A JP 14507779 A JP14507779 A JP 14507779A JP 14507779 A JP14507779 A JP 14507779A JP S5668685 A JPS5668685 A JP S5668685A
Authority
JP
Japan
Prior art keywords
formula
halogen
compound
lower alkyl
phenylimidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14507779A
Other languages
Japanese (ja)
Other versions
JPS6320236B2 (en
Inventor
Kiyoshi Murase
Toshiyasu Mase
Kenichi Tomioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Priority to JP14507779A priority Critical patent/JPS5668685A/en
Priority to FR8017896A priority patent/FR2463774A1/en
Priority to DE19803030982 priority patent/DE3030982A1/en
Priority to ES494397A priority patent/ES494397A0/en
Priority to IT68303/80A priority patent/IT1166483B/en
Priority to AT0425280A priority patent/ATA425280A/en
Priority to CA000358790A priority patent/CA1158246A/en
Priority to GB8027243A priority patent/GB2056982B/en
Publication of JPS5668685A publication Critical patent/JPS5668685A/en
Priority to US06/487,357 priority patent/US4497817A/en
Publication of JPS6320236B2 publication Critical patent/JPS6320236B2/ja
Granted legal-status Critical Current

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound formula I (R1, R2 and R3 are H, halogen, lower alkyl, OH, etc.; R4 is halogen, lower alkyl, lower alkoxyl, etc.; R5 is H, halogen, lower alkyl, etc.; X is H, halogen, nitroso, etc.; the dotted line is the presence or absence of a double bond) and a salt thereof.
EXAMPLE: 2-(m-Hydroxyphenyl)-7-methylimidazo[2,1-b]benzothiazole.
USE: An antiallergic, antiasthmatic, antirheumatic, anti-inflammatory, and carcinostatic agents and a remedy for autoimmune diseases. The derivative has a regulating action on the immune function.
PROCESS: A compound of formula II [A is carbonyl or group of formula III (Y is halogen)] is cyclized in a solvent, e.g. methanol, under heating to give the compound of formula I. Most of the compounds of formula II are novel substances and obtained by reacting a compound of formula IV with a compound of formula V.
COPYRIGHT: (C)1981,JPO&Japio
JP14507779A 1979-08-21 1979-11-09 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation Granted JPS5668685A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP14507779A JPS5668685A (en) 1979-11-09 1979-11-09 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation
FR8017896A FR2463774A1 (en) 1979-08-21 1980-08-13 DERIVATIVES OF 2-PHENYLIMIDAZO (2,1-B) BENZOTHIAZOLE
DE19803030982 DE3030982A1 (en) 1979-08-21 1980-08-16 2-PHENYLIMIDAZO (2,1-B) BENZOTHIAZOLE DERIVATIVES
AT0425280A ATA425280A (en) 1979-08-21 1980-08-20 METHOD FOR PRODUCING NEW 2-PHENYL-IMIDAZO (2.1-B) -BENZOTHIAZOLE DERIVATIVES
IT68303/80A IT1166483B (en) 1979-08-21 1980-08-20 DERIVATIVES OF 2 FENYLIMIDAZO 2 1 B BENZOTHIAZOLE HAVING AN IMMUNOREGULATORY EFFECT AND PROCEDURE FOR THEIR PREPARATION
ES494397A ES494397A0 (en) 1979-08-21 1980-08-20 A PRODUCTION PROCEDURE OF A 2-PHENYLIMI-DAZO (2,1-B) BENZOTIAZOLE DERIVATIVE
CA000358790A CA1158246A (en) 1979-08-21 1980-08-21 Process of producing 2-phenylimidazo¬2,1-b| benzothiazole derivatives
GB8027243A GB2056982B (en) 1979-08-21 1980-08-21 2 - phenylimidazo(2,1 - b)benzothiazole derivatives
US06/487,357 US4497817A (en) 1979-08-21 1983-04-26 2-Phenylimidazo [2,1-b]benzothiazole derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14507779A JPS5668685A (en) 1979-11-09 1979-11-09 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5668685A true JPS5668685A (en) 1981-06-09
JPS6320236B2 JPS6320236B2 (en) 1988-04-26

Family

ID=15376841

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14507779A Granted JPS5668685A (en) 1979-08-21 1979-11-09 2-phenylimidazo 2,1-b benzothiazole derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5668685A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968708A (en) * 1988-06-22 1990-11-06 Nikken Chemicals Co., Ltd. Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same
JP2007112513A (en) * 2005-09-22 2007-05-10 Nippon Paper-Pak Co Ltd Article supporting member

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968708A (en) * 1988-06-22 1990-11-06 Nikken Chemicals Co., Ltd. Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same
JP2007112513A (en) * 2005-09-22 2007-05-10 Nippon Paper-Pak Co Ltd Article supporting member

Also Published As

Publication number Publication date
JPS6320236B2 (en) 1988-04-26

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