GB201710229D0 - Compounds for new use - Google Patents

Compounds for new use

Info

Publication number
GB201710229D0
GB201710229D0 GBGB1710229.4A GB201710229A GB201710229D0 GB 201710229 D0 GB201710229 D0 GB 201710229D0 GB 201710229 A GB201710229 A GB 201710229A GB 201710229 D0 GB201710229 D0 GB 201710229D0
Authority
GB
United Kingdom
Prior art keywords
compounds
new use
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1710229.4A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tdeltas Ltd
Original Assignee
Tdeltas Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tdeltas Ltd filed Critical Tdeltas Ltd
Priority to GBGB1710229.4A priority Critical patent/GB201710229D0/en
Publication of GB201710229D0 publication Critical patent/GB201710229D0/en
Priority to JP2019572783A priority patent/JP7374000B2/ja
Priority to AU2018293398A priority patent/AU2018293398B2/en
Priority to KR1020207002473A priority patent/KR102680437B1/ko
Priority to TW107121496A priority patent/TWI811222B/zh
Priority to CA3066948A priority patent/CA3066948A1/en
Priority to US16/626,293 priority patent/US12439944B2/en
Priority to PL18737388.1T priority patent/PL3644982T3/pl
Priority to ES18737388T priority patent/ES2945964T3/es
Priority to GB1810300.2A priority patent/GB2567273B/en
Priority to EP18737388.1A priority patent/EP3644982B1/en
Priority to DK18737388.1T priority patent/DK3644982T3/da
Priority to CN201880042880.5A priority patent/CN110869012B/zh
Priority to PCT/GB2018/051752 priority patent/WO2019002828A1/en
Priority to EP23161905.7A priority patent/EP4215189A1/en
Priority to JP2023107837A priority patent/JP7632979B2/ja
Priority to US19/332,258 priority patent/US20260007157A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Meat, Egg Or Seafood Products (AREA)
GBGB1710229.4A 2017-06-27 2017-06-27 Compounds for new use Ceased GB201710229D0 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GBGB1710229.4A GB201710229D0 (en) 2017-06-27 2017-06-27 Compounds for new use
EP23161905.7A EP4215189A1 (en) 2017-06-27 2018-06-22 3-hydroxybutyrate compounds for use in reducing liver fat
ES18737388T ES2945964T3 (es) 2017-06-27 2018-06-22 Compuestos de 3-hidroxibutirato para la utilización en la reducción de la grasa hepática
EP18737388.1A EP3644982B1 (en) 2017-06-27 2018-06-22 3-hydroxybutyrate compounds for use in reducing liver fat
KR1020207002473A KR102680437B1 (ko) 2017-06-27 2018-06-22 간의 지방을 감소시키는 용도의 3-하이드록시부티레이트 화합물
TW107121496A TWI811222B (zh) 2017-06-27 2018-06-22 用於減少肝臟脂肪的3-羥基丁酸酯化合物
CA3066948A CA3066948A1 (en) 2017-06-27 2018-06-22 3-hydroxybutyrate compounds for use in reducing liver fat
US16/626,293 US12439944B2 (en) 2017-06-27 2018-06-22 3-hydroxybutyrate compounds for use in reducing liver fat
PL18737388.1T PL3644982T3 (pl) 2017-06-27 2018-06-22 Związki 3-hydroksymaślanu do zastosowania w redukowaniu tłuszczu wątrobowego
JP2019572783A JP7374000B2 (ja) 2017-06-27 2018-06-22 肝臓脂肪を減らすことにおいて使用するための３－ヒドロキシ酪酸化合物
GB1810300.2A GB2567273B (en) 2017-06-27 2018-06-22 Compounds for use in reducing liver fat
AU2018293398A AU2018293398B2 (en) 2017-06-27 2018-06-22 3-hydroxybutyrate compounds for use in reducing liver fat
DK18737388.1T DK3644982T3 (da) 2017-06-27 2018-06-22 3-hydroxybutyratforbindelser til anvendelse i reduktion af leverfedt
CN201880042880.5A CN110869012B (zh) 2017-06-27 2018-06-22 用于减少肝脏脂肪的3-羟基丁酸化合物
PCT/GB2018/051752 WO2019002828A1 (en) 2017-06-27 2018-06-22 3-HYDROXYBUTYRATE COMPOUNDS FOR USE IN THE REDUCTION OF HEPATIC FAT
JP2023107837A JP7632979B2 (ja) 2017-06-27 2023-06-30 肝臓脂肪を減らすことにおいて使用するための３－ヒドロキシ酪酸化合物
US19/332,258 US20260007157A1 (en) 2017-06-27 2025-09-18 3-hydroxybutyrate compounds for use in reducing liver fat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1710229.4A GB201710229D0 (en) 2017-06-27 2017-06-27 Compounds for new use

Publications (1)

Publication Number Publication Date
GB201710229D0 true GB201710229D0 (en) 2017-08-09

Family

ID=59523693

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1710229.4A Ceased GB201710229D0 (en) 2017-06-27 2017-06-27 Compounds for new use
GB1810300.2A Active GB2567273B (en) 2017-06-27 2018-06-22 Compounds for use in reducing liver fat

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1810300.2A Active GB2567273B (en) 2017-06-27 2018-06-22 Compounds for use in reducing liver fat

Country Status (13)

Country Link
US (2) US12439944B2 (https=)
EP (2) EP4215189A1 (https=)
JP (2) JP7374000B2 (https=)
KR (1) KR102680437B1 (https=)
CN (1) CN110869012B (https=)
AU (1) AU2018293398B2 (https=)
CA (1) CA3066948A1 (https=)
DK (1) DK3644982T3 (https=)
ES (1) ES2945964T3 (https=)
GB (2) GB201710229D0 (https=)
PL (1) PL3644982T3 (https=)
TW (1) TWI811222B (https=)
WO (1) WO2019002828A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201710229D0 (en) * 2017-06-27 2017-08-09 Tdeltas Ltd Compounds for new use
GB201715654D0 (en) 2017-09-27 2017-11-08 Tdeltas Ltd Method of treatment
GB2577723A (en) 2018-10-04 2020-04-08 Tdeltas Ltd Compounds for new use
ES2941943T3 (es) 2019-01-17 2023-05-26 Ketolipix Therapeutics Gmbh Método para la producción de glicéridos de ácidos hidroxicarboxílicos
CN109700021A (zh) * 2019-03-04 2019-05-03 清华大学 3-羟基丁酸及其衍生物在制备预防和治疗肥胖及肥胖相关疾病的产品中的应用
CN110776425B (zh) * 2019-10-23 2021-02-26 清华大学 一种(r)-3-羟基丁酸及其低聚物的制备方法
JP7638693B2 (ja) * 2020-12-15 2025-03-04 大阪瓦斯株式会社 ヒドロキシアルカン酸結晶の製造方法及びヒドロキシアルカン酸の結晶多形体
US20240196917A1 (en) * 2021-06-01 2024-06-20 Osaka Gas Co., Ltd. Oil and fat composition containing 3-hydroxybutyric acid
WO2023283654A1 (en) * 2021-07-09 2023-01-12 Georgia State University Research Foundation, Inc. The use of beta-hydroxybutyrates for the treatment or prevention of aneurysms and dissections
IT202100020441A1 (it) * 2021-07-30 2023-01-30 Unichem Estense S R L Miscela di un mono-estere e un di-estere, in cui detti mono-estere e di-estere sono esteri dell’acido (R)-3-idrossibutanoico con un polialcol, processo per la preparazione della miscela e relativi usi medici
CN113712140A (zh) * 2021-09-13 2021-11-30 珠海麦得发生物科技股份有限公司 一种含(r)-3羟基丁酸的固体饮料及其制备方法
AU2022381752B2 (en) * 2021-11-04 2026-01-08 Vdf Futureceuticals, Inc Ketone precursors and methods therefor
CN118591523A (zh) * 2021-11-12 2024-09-03 阿萨达股份公司 多元醇衍生的化合物
AU2022411334A1 (en) * 2021-12-14 2024-06-13 Suntory Holdings Limited Carbonated beverage, and method for enhancing sense of carbonation of beverage
CN118382365A (zh) * 2021-12-14 2024-07-23 三得利控股株式会社 含有3羟基丁酸及低级脂肪族醇的饮料及呈味改善方法
JP7223193B1 (ja) 2022-05-26 2023-02-15 大阪瓦斯株式会社 内臓脂肪低減剤およびその用途
CN116966173A (zh) * 2023-06-15 2023-10-31 浙江大学 3-羟基苯乙酸在制备改善非酒精性脂肪肝药物中的应用
CN118903420A (zh) * 2024-07-02 2024-11-08 南方医科大学 Irf4抑制剂在治疗非酒精性脂肪性肝炎的应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1248321B (it) * 1991-05-15 1995-01-05 Sigma Tau Ind Farmaceuti Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie
US6323237B1 (en) 1997-03-17 2001-11-27 Btg International Limited Therapeutic compositions
US20090253781A1 (en) 2002-05-24 2009-10-08 Btg International Limited Therapeutic compositions
CN1315473C (zh) 1997-03-17 2007-05-16 英国技术集团国际有限公司 治疗组合物
EP2258742A1 (en) * 1997-12-22 2010-12-08 Metabolix, Inc. Polyhydroxyalkanoate compositons having controlled degradation rates
EP2275468A1 (en) * 2000-07-14 2011-01-19 Metabolix, Inc. Polyurethanes obtained from hydroxyalkanoates and isocyanates
EP1648952B1 (en) * 2003-06-03 2018-03-07 THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Nutritional supplements and therapeutic compositions comprising (r)-3-hydroxybutyrate derivatives
SE0400355D0 (sv) * 2004-02-17 2004-02-17 Synbiotics Ab New synbiotec use
WO2006020137A2 (en) * 2004-07-16 2006-02-23 Ketocytonyx Inc. Oligomeric compounds
EP1778615A4 (en) 2004-07-20 2010-01-06 Btg Int Ltd OLIGOMERE KETONE COMPOUNDS
WO2008110034A1 (en) 2007-03-14 2008-09-18 Shantou University 3-hydroxy fatty acid and its derivatives for improving of learning and/or memory of subjects
EP2240017B1 (en) 2008-01-04 2019-03-13 Oxford University Innovation Limited Ketone bodies and ketone body esters as blood lipid lowering agents
US8642654B2 (en) 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
JP5773870B2 (ja) * 2008-08-21 2015-09-02 アイシス イノヴェイション リミテッド ヒドロキシ酪酸エステル及びその医学的使用
WO2011078204A1 (ja) 2009-12-24 2011-06-30 浜理薬品工業株式会社 高脂血症の予防または治療剤、および抗疲労剤
US8865641B2 (en) * 2011-06-16 2014-10-21 The Feinstein Institute For Medical Research Methods of treatment of fatty liver disease by pharmacological activation of cholinergic pathways
GB201206192D0 (en) 2012-04-05 2012-05-23 Tdeltas Ltd Ketone bodies and ketone body esters and for maintaining or improving muscle power output
GB2515603B (en) 2013-03-14 2015-10-14 Isis Innovation Process for producing (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate
CA2902603C (en) 2013-03-19 2021-03-02 University Of South Florida Compositions and methods for producing elevated and sustained ketosis
IN2013MU01468A (https=) * 2013-04-22 2015-04-17 Cadila Healthcare Ltd
US11814664B2 (en) * 2013-05-24 2023-11-14 Genomatica, Inc. Microorganisms and methods for producing (3R)-hydroxybutyl (3R)-hydroxybutyrate
GB201314127D0 (en) 2013-08-07 2013-09-18 Tdeltas Ltd Ketone body and ketone body ester for reducing muscle breakdown
US20150283163A1 (en) 2014-04-04 2015-10-08 Organic Medical Ventures, L.L.C. Muscle treatment composition and method making same
US20180008629A1 (en) 2015-01-29 2018-01-11 Yale University Compositions and Methods for Treating NLRP3 Inflammasome-Related Diseases and Disorders
EA201791982A1 (ru) * 2015-03-09 2020-02-17 Интекрин Терапьютикс, Инк. Способы лечения неалкогольной жировой болезни печени и/или липодистрофии
CA3021784A1 (en) 2016-04-19 2017-10-26 Keto Patent Group, Inc. Administration of butyrate, beta-hydroxybutyrate, and related compounds in humans
US10336812B2 (en) * 2016-05-10 2019-07-02 Janssen Biotech, Inc. GDF15 fusion proteins and uses thereof
GB201710229D0 (en) 2017-06-27 2017-08-09 Tdeltas Ltd Compounds for new use

Also Published As

Publication number Publication date
US12439944B2 (en) 2025-10-14
AU2018293398A1 (en) 2020-01-16
TW201904568A (zh) 2019-02-01
JP2023120442A (ja) 2023-08-29
KR102680437B1 (ko) 2024-07-01
EP4215189A1 (en) 2023-07-26
AU2018293398B2 (en) 2023-11-23
JP7632979B2 (ja) 2025-02-19
ES2945964T3 (es) 2023-07-11
GB201810300D0 (en) 2018-08-08
JP7374000B2 (ja) 2023-11-06
EP3644982A1 (en) 2020-05-06
CA3066948A1 (en) 2019-01-03
KR20200019745A (ko) 2020-02-24
GB2567273A (en) 2019-04-10
TWI811222B (zh) 2023-08-11
CN110869012A (zh) 2020-03-06
CN110869012B (zh) 2024-06-11
DK3644982T3 (da) 2023-07-17
JP2020527547A (ja) 2020-09-10
US20200113220A1 (en) 2020-04-16
PL3644982T3 (pl) 2023-08-14
GB2567273B (en) 2020-10-07
WO2019002828A1 (en) 2019-01-03
US20260007157A1 (en) 2026-01-08
EP3644982B1 (en) 2023-04-12

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)