GB201613054D0 - New compound and process - Google Patents

New compound and process

Info

Publication number
GB201613054D0
GB201613054D0 GBGB1613054.4A GB201613054A GB201613054D0 GB 201613054 D0 GB201613054 D0 GB 201613054D0 GB 201613054 A GB201613054 A GB 201613054A GB 201613054 D0 GB201613054 D0 GB 201613054D0
Authority
GB
United Kingdom
Prior art keywords
new compound
compound
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1613054.4A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Verona Pharma Ltd
Original Assignee
Verona Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verona Pharma Ltd filed Critical Verona Pharma Ltd
Priority to GBGB1613054.4A priority Critical patent/GB201613054D0/en
Publication of GB201613054D0 publication Critical patent/GB201613054D0/en
Priority to SI201730098T priority patent/SI3490988T1/sl
Priority to LTEP17748880.6T priority patent/LT3490988T/lt
Priority to EP17748880.6A priority patent/EP3490988B1/en
Priority to TW106125312A priority patent/TWI739871B/zh
Priority to HRP20192109TT priority patent/HRP20192109T1/hr
Priority to JP2019503748A priority patent/JP6985367B2/ja
Priority to US16/309,435 priority patent/US10710998B2/en
Priority to RS20191474A priority patent/RS59566B1/sr
Priority to PCT/GB2017/052190 priority patent/WO2018020249A1/en
Priority to PT177488806T priority patent/PT3490988T/pt
Priority to PL17748880T priority patent/PL3490988T3/pl
Priority to DK17748880T priority patent/DK3490988T3/da
Priority to KR1020197004436A priority patent/KR102396059B1/ko
Priority to HUE17748880A priority patent/HUE046509T2/hu
Priority to ES17748880T priority patent/ES2751948T3/es
Priority to SM20190582T priority patent/SMT201900582T1/it
Priority to CN201780046788.1A priority patent/CN109641891B/zh
Priority to CY20191101046T priority patent/CY1122138T1/el
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GBGB1613054.4A 2016-07-28 2016-07-28 New compound and process Ceased GB201613054D0 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
GBGB1613054.4A GB201613054D0 (en) 2016-07-28 2016-07-28 New compound and process
CN201780046788.1A CN109641891B (zh) 2016-07-28 2017-07-27 新化合物和方法
RS20191474A RS59566B1 (sr) 2016-07-28 2017-07-27 Novo jedinjenje i postupak
PT177488806T PT3490988T (pt) 2016-07-28 2017-07-27 Novo composto e processo
EP17748880.6A EP3490988B1 (en) 2016-07-28 2017-07-27 New compound and process
TW106125312A TWI739871B (zh) 2016-07-28 2017-07-27 新化合物及方法
HRP20192109TT HRP20192109T1 (hr) 2016-07-28 2017-07-27 Novi spoj i proces
JP2019503748A JP6985367B2 (ja) 2016-07-28 2017-07-27 新規化合物および方法
US16/309,435 US10710998B2 (en) 2016-07-28 2017-07-27 Compound and process
SI201730098T SI3490988T1 (sl) 2016-07-28 2017-07-27 Nova spojina in postopek
PCT/GB2017/052190 WO2018020249A1 (en) 2016-07-28 2017-07-27 New compound and process
LTEP17748880.6T LT3490988T (lt) 2016-07-28 2017-07-27 Naujas junginys ir gavimo būdas
PL17748880T PL3490988T3 (pl) 2016-07-28 2017-07-27 Nowy związek i sposób
DK17748880T DK3490988T3 (da) 2016-07-28 2017-07-27 Ny forbindelse og fremgangsmåde
KR1020197004436A KR102396059B1 (ko) 2016-07-28 2017-07-27 신규 화합물 및 이의 제조방법
HUE17748880A HUE046509T2 (hu) 2016-07-28 2017-07-27 Új vegyület és eljárás
ES17748880T ES2751948T3 (es) 2016-07-28 2017-07-27 Nuevo compuesto y proceso
SM20190582T SMT201900582T1 (it) 2016-07-28 2017-07-27 Nuovo composto e procedimento
CY20191101046T CY1122138T1 (el) 2016-07-28 2019-10-04 Νεα ενωση και διαδικασια

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1613054.4A GB201613054D0 (en) 2016-07-28 2016-07-28 New compound and process

Publications (1)

Publication Number Publication Date
GB201613054D0 true GB201613054D0 (en) 2016-09-14

Family

ID=56936838

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1613054.4A Ceased GB201613054D0 (en) 2016-07-28 2016-07-28 New compound and process

Country Status (19)

Country Link
US (1) US10710998B2 (enExample)
EP (1) EP3490988B1 (enExample)
JP (1) JP6985367B2 (enExample)
KR (1) KR102396059B1 (enExample)
CN (1) CN109641891B (enExample)
CY (1) CY1122138T1 (enExample)
DK (1) DK3490988T3 (enExample)
ES (1) ES2751948T3 (enExample)
GB (1) GB201613054D0 (enExample)
HR (1) HRP20192109T1 (enExample)
HU (1) HUE046509T2 (enExample)
LT (1) LT3490988T (enExample)
PL (1) PL3490988T3 (enExample)
PT (1) PT3490988T (enExample)
RS (1) RS59566B1 (enExample)
SI (1) SI3490988T1 (enExample)
SM (1) SMT201900582T1 (enExample)
TW (1) TWI739871B (enExample)
WO (1) WO2018020249A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3231444T3 (pl) 2014-05-12 2020-05-18 Verona Pharma Plc Nowe leczenie
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
AU2021207775B2 (en) * 2020-01-17 2025-12-11 Lupin Limited Methods, processes and intermediates for preparing chroman compounds
TW202302587A (zh) 2021-04-29 2023-01-16 大陸商蘇州盛迪亞生物醫藥有限公司 異喹啉酮類化合物及其用途
KR20240119082A (ko) * 2021-12-14 2024-08-06 시젱 하이스코 파마수티칼 씨오., 엘티디. 트리사이클릭 융합된 헤테로사이클릭 pde3/4 이중 억제제 및 이의 용도
GB202202297D0 (en) 2022-02-21 2022-04-06 Verona Pharma Plc Formulation production process
EP4378942A1 (en) 2022-12-02 2024-06-05 Sandoz AG Crystal form of a pde3/4 inhibitor
WO2025003643A1 (en) 2023-06-26 2025-01-02 Verona Pharma Plc Particulate composition comprising ensifetrine
US12194045B1 (en) 2023-06-26 2025-01-14 Verona Pharma Plc Particulate composition
US20250073240A1 (en) 2023-09-06 2025-03-06 Verona Pharma Plc New treatment
WO2025168708A1 (en) 2024-02-07 2025-08-14 Verona Pharma Plc Pharmaceutical compositions of ensifentrine for chronic obstructive pulmonary disease
WO2025168706A1 (en) 2024-02-07 2025-08-14 Verona Pharma Plc Pharmaceutical compositions of ensifentrine for chronic obstructive pulmonary disease
WO2025176871A1 (en) 2024-02-23 2025-08-28 Inke, S.A. Process for preparing pyrimido[6,1-a]isoquinoline-4-ones

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ185900A (en) 1976-12-10 1981-04-24 Hoechst Ag Pyrimido (6,1-a) isoquinolin-4-ones medicaments intermediate isoquinolines
FI64370C (fi) 1977-05-05 1983-11-10 Hoechst Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara pyimido-(6,1-a)isokinolin-2-imino-4-onderivat
DE2847693A1 (de) 1978-11-03 1980-05-22 Hoechst Ag Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
DE3135831A1 (de) 1981-09-10 1983-04-28 Hoechst Ag, 6230 Frankfurt 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CA1237429A (en) 1983-05-05 1988-05-31 Frank Kienzle Pyrimidone derivatives
DE60005493T2 (de) * 1999-03-31 2004-07-01 Vernalis Ltd., Wokingham Pyrimido[6,1-a]isochinolinonderivate
MX345802B (es) 2010-08-09 2017-02-16 Verona Pharma Plc * Forma cristalina de compuesto pirimido [6, 1-a] isoquinolin-4-ona.
RU2666624C2 (ru) 2013-03-15 2018-09-11 ВЕРОНА ФАРМА ПиэЛСи Комбинация лекарственных средств
PL3231444T3 (pl) 2014-05-12 2020-05-18 Verona Pharma Plc Nowe leczenie
RU2699995C2 (ru) 2014-09-15 2019-09-12 ВЕРОНА ФАРМА ПиэЛСи Жидкая ингаляционная композиция, содержащая rpl 554
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound

Also Published As

Publication number Publication date
TW201806951A (zh) 2018-03-01
WO2018020249A1 (en) 2018-02-01
CY1122138T1 (el) 2020-11-25
US20190330206A1 (en) 2019-10-31
RS59566B1 (sr) 2019-12-31
DK3490988T3 (da) 2019-10-28
US10710998B2 (en) 2020-07-14
HRP20192109T1 (hr) 2020-02-21
KR102396059B1 (ko) 2022-05-10
JP2019527228A (ja) 2019-09-26
HUE046509T2 (hu) 2020-03-30
CN109641891B (zh) 2021-05-04
CN109641891A (zh) 2019-04-16
JP6985367B2 (ja) 2021-12-22
EP3490988B1 (en) 2019-08-28
TWI739871B (zh) 2021-09-21
PL3490988T3 (pl) 2020-02-28
SMT201900582T1 (it) 2019-11-13
PT3490988T (pt) 2019-10-28
SI3490988T1 (sl) 2019-11-29
ES2751948T3 (es) 2020-04-02
LT3490988T (lt) 2019-10-10
EP3490988A1 (en) 2019-06-05
KR20190034231A (ko) 2019-04-01

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)