GB201013989D0 - Biological materials and methods of using the same - Google Patents

Biological materials and methods of using the same

Info

Publication number
GB201013989D0
GB201013989D0 GBGB1013989.7A GB201013989A GB201013989D0 GB 201013989 D0 GB201013989 D0 GB 201013989D0 GB 201013989 A GB201013989 A GB 201013989A GB 201013989 D0 GB201013989 D0 GB 201013989D0
Authority
GB
United Kingdom
Prior art keywords
methods
same
biological materials
biological
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1013989.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southampton
Original Assignee
University of Southampton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Southampton filed Critical University of Southampton
Priority to GBGB1013989.7A priority Critical patent/GB201013989D0/en
Publication of GB201013989D0 publication Critical patent/GB201013989D0/en
Priority to PL11760819T priority patent/PL2606068T3/pl
Priority to CN202110959352.XA priority patent/CN114099666B/zh
Priority to EP11760819.0A priority patent/EP2606068B1/en
Priority to CN202110959481.9A priority patent/CN114099669A/zh
Priority to US13/817,744 priority patent/US10525129B2/en
Priority to RU2017143633A priority patent/RU2769949C2/ru
Priority to PT117608190T priority patent/PT2606068T/pt
Priority to SI201131366T priority patent/SI2606068T1/en
Priority to ES11760819.0T priority patent/ES2653685T3/es
Priority to CN202110959354.9A priority patent/CN114099668B/zh
Priority to DK11760819.0T priority patent/DK2606068T3/da
Priority to CN201180040351XA priority patent/CN103080131A/zh
Priority to JP2013524483A priority patent/JP6215704B2/ja
Priority to RU2013112345/10A priority patent/RU2013112345A/ru
Priority to CN201710789909.3A priority patent/CN107670034B/zh
Priority to HUE11760819A priority patent/HUE037478T2/hu
Priority to NO11760819A priority patent/NO2606068T3/no
Priority to PCT/GB2011/051572 priority patent/WO2012022985A1/en
Priority to AU2011290503A priority patent/AU2011290503B2/en
Priority to EP17184259.4A priority patent/EP3263602A1/en
Priority to KR1020137006990A priority patent/KR101948609B1/ko
Priority to CN202110959355.3A priority patent/CN114099702B/zh
Priority to CA2808744A priority patent/CA2808744C/en
Priority to CN202110959353.4A priority patent/CN114099667B/zh
Priority to JP2016078639A priority patent/JP6421140B2/ja
Priority to US16/684,450 priority patent/US11623005B2/en
Priority to US17/359,496 priority patent/US20210346498A1/en
Priority to US18/177,050 priority patent/US20230381310A1/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
GBGB1013989.7A 2010-08-20 2010-08-20 Biological materials and methods of using the same Ceased GB201013989D0 (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
GBGB1013989.7A GB201013989D0 (en) 2010-08-20 2010-08-20 Biological materials and methods of using the same
CN202110959353.4A CN114099667B (zh) 2010-08-20 2011-08-19 FcγRIIB(CD32B)和CD20特异性抗体的组合应用
RU2013112345/10A RU2013112345A (ru) 2010-08-20 2011-08-19 Биологические материалы и способы их применения
CN201710789909.3A CN107670034B (zh) 2010-08-20 2011-08-19 FcγRIIB(CD32B)和CD20特异性抗体的组合应用
EP11760819.0A EP2606068B1 (en) 2010-08-20 2011-08-19 COMBINED USE OF FC GAMMA RIIB (CD32B) AND CD19-, CD20- or CD40- SPECIFIC ANTIBODIES
CN202110959481.9A CN114099669A (zh) 2010-08-20 2011-08-19 FcγRIIB(CD32B)和CD20特异性抗体的组合应用
US13/817,744 US10525129B2 (en) 2010-08-20 2011-08-19 Combined use of Fc gamma RIIb (CD32B) and CD20-specific antibodies
RU2017143633A RU2769949C2 (ru) 2010-08-20 2011-08-19 Биологические материалы и способы их применения
PT117608190T PT2606068T (pt) 2010-08-20 2011-08-19 Utilização combinada de fc gama riib (cd32b) e anticorpos específicos para cd19, cd20 ou cd40
SI201131366T SI2606068T1 (en) 2010-08-20 2011-08-19 The combined use of FC gamma RIIb (CD32B) and CD19-, CD20- or CD40-specific antibodies
ES11760819.0T ES2653685T3 (es) 2010-08-20 2011-08-19 Uso combinado de Fc gamma RIIB (CD32B) y de anticuerpos específicos de CD19, CD20 o CD40
CN202110959354.9A CN114099668B (zh) 2010-08-20 2011-08-19 FcγRIIB(CD32B)和CD20特异性抗体的组合应用
DK11760819.0T DK2606068T3 (da) 2010-08-20 2011-08-19 Kombineret anvendelse af fc gamma riib (cd32b) og cd19-, cd20- eller cd40-specifikke antistoffer
CN201180040351XA CN103080131A (zh) 2010-08-20 2011-08-19 FcγRIIB(CD32B)和CD20特异性抗体的组合应用
JP2013524483A JP6215704B2 (ja) 2010-08-20 2011-08-19 Fcガンマriib(cd32b)特異的抗体およびcd20特異的抗体の併用使用
PL11760819T PL2606068T3 (pl) 2010-08-20 2011-08-19 SKOJARZONE ZASTOSOWANIE PRZECIWCIAŁ SPECYFICZNYCH WZGLĘDEM GAMMA RIIB (CD32B) I CD19, CD20 lub CD40
NO11760819A NO2606068T3 (enExample) 2010-08-20 2011-08-19
EP17184259.4A EP3263602A1 (en) 2010-08-20 2011-08-19 Combined use of fc gamma rub (cd32b) and cd20 specific antibodies
HUE11760819A HUE037478T2 (hu) 2010-08-20 2011-08-19 Fc gamma RIIB (CD32B) és CD19-, CD20- vagy CD40- specifikus ellenanyagok kombinált alkalmazása
PCT/GB2011/051572 WO2012022985A1 (en) 2010-08-20 2011-08-19 Combined use of fc gamma riib (cd32b) and cd20 - specific antibodies
AU2011290503A AU2011290503B2 (en) 2010-08-20 2011-08-19 Combined use of Fc gamma RIIb (CD32B) and CD20 - specific antibodies
CN202110959352.XA CN114099666B (zh) 2010-08-20 2011-08-19 FcγRIIB(CD32B)和CD20特异性抗体的组合应用
KR1020137006990A KR101948609B1 (ko) 2010-08-20 2011-08-19 Fc 감마 riib(cd32b) 및 cd20 - 특이적 항체의 복합 용도
CN202110959355.3A CN114099702B (zh) 2010-08-20 2011-08-19 FcγRIIB(CD32B)和CD20特异性抗体的组合应用
CA2808744A CA2808744C (en) 2010-08-20 2011-08-19 Combined use of fc gamma riib (cd32b) and cd20 specific antibodies
JP2016078639A JP6421140B2 (ja) 2010-08-20 2016-04-11 Fcガンマriib(cd32b)特異的抗体およびcd20特異的抗体の併用使用
US16/684,450 US11623005B2 (en) 2010-08-20 2019-11-14 Combined use of FcγRIIb (CD32B) and CD20 specific antibodies
US17/359,496 US20210346498A1 (en) 2010-08-20 2021-06-25 Combined use of fc gamma riib (cd32b) and cd20 specific antibodies
US18/177,050 US20230381310A1 (en) 2010-08-20 2023-03-01 Combined use of fc gamma riib (cd32b) and cd20 specific antibodies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1013989.7A GB201013989D0 (en) 2010-08-20 2010-08-20 Biological materials and methods of using the same

Publications (1)

Publication Number Publication Date
GB201013989D0 true GB201013989D0 (en) 2010-10-06

Family

ID=42984443

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1013989.7A Ceased GB201013989D0 (en) 2010-08-20 2010-08-20 Biological materials and methods of using the same

Country Status (17)

Country Link
US (4) US10525129B2 (enExample)
EP (2) EP3263602A1 (enExample)
JP (2) JP6215704B2 (enExample)
KR (1) KR101948609B1 (enExample)
CN (7) CN114099667B (enExample)
AU (1) AU2011290503B2 (enExample)
CA (1) CA2808744C (enExample)
DK (1) DK2606068T3 (enExample)
ES (1) ES2653685T3 (enExample)
GB (1) GB201013989D0 (enExample)
HU (1) HUE037478T2 (enExample)
NO (1) NO2606068T3 (enExample)
PL (1) PL2606068T3 (enExample)
PT (1) PT2606068T (enExample)
RU (2) RU2769949C2 (enExample)
SI (1) SI2606068T1 (enExample)
WO (1) WO2012022985A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201013989D0 (en) 2010-08-20 2010-10-06 Univ Southampton Biological materials and methods of using the same
RU2015125349A (ru) * 2012-11-29 2017-01-10 Байер Хелскеа Ллк МОНОКЛОНАЛЬНЫЕ АНТИТЕЛА ПРОТИВ АКТИВИРОВАННОГО БЕЛКА С (аРС)
ES2730690T3 (es) * 2012-12-07 2019-11-12 Suppremol Gmbh Estratificación y tratamiento de pacientes que padecen púrpura trombocitopénica idiopática
EP3666795A1 (en) 2013-03-12 2020-06-17 Molecular Templates, Inc. Cytotoxic proteins comprising cell-targeting binding regions and shiga toxin a subunit regions for selective killing of specific cell types
EP2833139A1 (en) * 2013-08-01 2015-02-04 SuppreMol GmbH In vitro method for determining the stability of compositions comprising soluble Fc gamma receptor(s)
EP3575312A1 (en) 2014-01-27 2019-12-04 Molecular Templates, Inc. De-immunized shiga toxin a subunit effector polypeptides for applications in mammals
US11142584B2 (en) 2014-03-11 2021-10-12 Molecular Templates, Inc. CD20-binding proteins comprising Shiga toxin A subunit effector regions for inducing cellular internalization and methods using same
GB2526139A (en) 2014-05-15 2015-11-18 Biolnvent Internat Ab Medicaments, uses and methods
EP3137488B1 (en) 2014-06-11 2019-01-02 Molecular Templates, Inc. Protease-cleavage resistant, shiga toxin a subunit effector polypeptides and cell-targeting molecules comprising the same
EP3253799B1 (en) 2015-02-05 2020-12-02 Molecular Templates, Inc. Multivalent cd20-binding molecules comprising shiga toxin a subunit effector regions and enriched compositions thereof
CA2975660A1 (en) * 2015-03-16 2016-09-22 Helmholtz Zentrum Munchen - Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) Trispecific binding molecules for treating hbv infection and associated conditions
MX2017015493A (es) 2015-05-30 2018-02-09 Molecular Templates Inc Andamiajes de la subunidad a de la toxina shiga desinmunizados y moleculas con direccion a las celulas que los comprenden.
UY37030A (es) 2015-12-18 2017-07-31 Novartis Ag Anticuerpos dirigidos a cd32b y métodos de uso de los mismos
EP3551047A1 (en) 2016-12-07 2019-10-16 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
AU2017373962B2 (en) 2016-12-07 2022-03-31 Molecular Templates, Inc. Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
AU2018213194B2 (en) 2017-01-25 2023-01-12 Molecular Templates, Inc. Cell-targeting molecules comprising de-immunized, Shiga toxin A Subunit effectors and CD8+ T-cell epitopes
EP3573640A4 (en) * 2017-01-30 2021-04-28 The Ohio State Innovation Foundation PASSIVE ANTIBODY DEPENDENT CELLULAR MEDIATION ACTIVATION
US20210138213A1 (en) 2017-03-30 2021-05-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
WO2018229706A1 (en) 2017-06-16 2018-12-20 Novartis Ag Combination therapy for the treatment of cancer
WO2018229715A1 (en) 2017-06-16 2018-12-20 Novartis Ag Compositions comprising anti-cd32b antibodies and methods of use thereof
US20210040205A1 (en) 2017-10-25 2021-02-11 Novartis Ag Antibodies targeting cd32b and methods of use thereof
TW201925782A (zh) 2017-11-30 2019-07-01 瑞士商諾華公司 靶向bcma之嵌合抗原受體及其用途
CA3097178A1 (en) 2018-04-17 2019-10-24 Molecular Templates, Inc. Her2-targeting molecules comprising de-immunized, shiga toxin a subunit scaffolds
CN108823211A (zh) * 2018-05-04 2018-11-16 中国医学科学院基础医学研究所 一种cd19核酸适配体及其应用
TWI848951B (zh) 2018-06-01 2024-07-21 瑞士商諾華公司 針對bcma之結合分子及其用途
US20230041197A1 (en) 2018-06-20 2023-02-09 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
WO2019246317A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease or condition in a tissue originating from the endoderm
CN116726362A (zh) 2018-11-19 2023-09-12 比奥拉治疗股份有限公司 用生物治疗剂治疗疾病的方法和装置
AU2020315163B2 (en) * 2019-07-17 2025-11-20 Bioinvent International Ab Antibody combinations for treatment of cancer in specific patients
CR20220166A (es) * 2019-10-18 2022-06-15 Genentech Inc Métodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes
CN115666704B (zh) 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
EP3919077A1 (en) 2020-06-04 2021-12-08 BioInvent International AB Model for prediction of tolerability issues in connection with intravenous administration of therapeutic antibodies
TW202210103A (zh) 2020-06-04 2022-03-16 瑞典商生物創新國際有限公司 治療系統、方法及用途
AU2021373366A1 (en) 2020-11-06 2023-06-01 Novartis Ag Cd19 binding molecules and uses thereof
TW202336033A (zh) 2022-03-07 2023-09-16 瑞典商生物創新國際有限公司 抗體之新穎組合及用途
US20230399375A1 (en) 2022-04-15 2023-12-14 Kyverna Therapeutics, Inc. Methods and compositions for treating autoimmune disease
WO2023240064A1 (en) 2022-06-08 2023-12-14 Kyverna Therapeutics, Inc. Methods and compositions for treating autoimmune disease

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US4880078A (en) 1987-06-29 1989-11-14 Honda Giken Kogyo Kabushiki Kaisha Exhaust muffler
JPH06507404A (ja) 1991-05-01 1994-08-25 ヘンリー エム.ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン 感染性の呼吸性疾患の治療方法
US5934272A (en) 1993-01-29 1999-08-10 Aradigm Corporation Device and method of creating aerosolized mist of respiratory drug
US6019968A (en) 1995-04-14 2000-02-01 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
ATE508733T1 (de) 1996-03-04 2011-05-15 Penn State Res Found Materialien und verfahren zur steigerung der zellulären internalisierung
US5985309A (en) 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US5855913A (en) 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
WO1998031346A1 (en) 1997-01-16 1998-07-23 Massachusetts Institute Of Technology Preparation of particles for inhalation
CA2336139C (en) 1998-06-24 2008-10-14 Advanced Inhalation Research, Inc. Large porous particles emitted from an inhaler
IL149500A0 (en) * 1999-11-08 2002-11-10 Idec Pharma Corp Treatment of b cell malignancies using anti-cd40l antibodies in combination with anti-cd20 antibodies and/or chemotherapeutics and radiotherapy
JP4459810B2 (ja) * 2002-08-14 2010-04-28 マクロジェニクス,インコーポレーテッド FcγRIIB特異的抗体とその利用法
US20050260213A1 (en) 2004-04-16 2005-11-24 Scott Koenig Fcgamma-RIIB-specific antibodies and methods of use thereof
US20090010920A1 (en) 2003-03-03 2009-01-08 Xencor, Inc. Fc Variants Having Decreased Affinity for FcyRIIb
WO2005018669A1 (en) * 2003-08-18 2005-03-03 Macrogenics, Inc. Fcϝriib-specific antibodies and methods of use thereof
ES2371468T3 (es) 2003-11-26 2012-01-03 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. SUSTANCIA QUE SE UNE AL RECEPTOR HUMANO llb MEDIANTE Fc DE IgG (Fc? Rllb).
CN101001872A (zh) * 2004-04-16 2007-07-18 宏观基因有限公司 FcγRIIB-特异性抗体及其使用方法
CA2565874C (en) 2004-05-10 2017-10-03 Macrogenics, Inc. Humanized fc.gamma.riib-specific antibodies and methods of use thereof
CN101522714A (zh) * 2004-05-20 2009-09-02 圣玛莉医院国民健康保险基金 用于治疗过敏性疾病的IgE重定位、功能性改变分子(ERFAM)
AU2005335714B2 (en) 2004-11-10 2012-07-26 Macrogenics, Inc. Engineering Fc antibody regions to confer effector function
CA2590935C (en) * 2004-12-15 2014-09-30 Macrogenics, Inc. Fc.gamma.riib-specific antibodies and methods of use thereof
EP1674479A1 (en) * 2004-12-22 2006-06-28 Memorial Sloan-Kettering Cancer Center Modulation of Fc Gamma receptors for optimizing immunotherapy
CA2656224C (en) * 2006-06-26 2018-01-09 Macrogenics, Inc. Combination of fc.gamma.riib antibodies and cd20-specific antibodies and methods of use thereof
US8652466B2 (en) 2006-12-08 2014-02-18 Macrogenics, Inc. Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting
US20120030144A1 (en) * 2007-11-08 2012-02-02 Pikamab, Inc. Methods for doing business using biomarkers
EP2234641B1 (en) * 2008-01-03 2015-08-19 Genmab A/S Monoclonal antibodies against cd32b
US20110268753A1 (en) 2009-01-08 2011-11-03 The Uab Research Foundation Process for regulating immune response
GB201013989D0 (en) * 2010-08-20 2010-10-06 Univ Southampton Biological materials and methods of using the same
GB2526139A (en) 2014-05-15 2015-11-18 Biolnvent Internat Ab Medicaments, uses and methods

Also Published As

Publication number Publication date
KR20140005866A (ko) 2014-01-15
CN114099666B (zh) 2025-05-02
EP3263602A1 (en) 2018-01-03
KR101948609B1 (ko) 2019-02-15
CA2808744C (en) 2023-03-07
CN114099669A (zh) 2022-03-01
ES2653685T3 (es) 2018-02-08
WO2012022985A1 (en) 2012-02-23
US20210346498A1 (en) 2021-11-11
HUE037478T2 (hu) 2018-08-28
US20230381310A1 (en) 2023-11-30
RU2013112345A (ru) 2014-09-27
JP2013537547A (ja) 2013-10-03
US20130251706A1 (en) 2013-09-26
CN114099666A (zh) 2022-03-01
CN103080131A (zh) 2013-05-01
DK2606068T3 (da) 2017-11-20
JP2016138129A (ja) 2016-08-04
EP2606068A1 (en) 2013-06-26
JP6215704B2 (ja) 2017-10-18
NO2606068T3 (enExample) 2018-02-24
CN114099702A (zh) 2022-03-01
AU2011290503A1 (en) 2013-03-07
CN114099668A (zh) 2022-03-01
CN114099702B (zh) 2024-08-27
RU2017143633A3 (enExample) 2021-01-29
RU2017143633A (ru) 2019-02-14
AU2011290503B2 (en) 2015-09-03
PT2606068T (pt) 2017-12-29
CN107670034B (zh) 2021-07-20
SI2606068T1 (en) 2018-01-31
US20200069798A1 (en) 2020-03-05
CN114099667A (zh) 2022-03-01
US11623005B2 (en) 2023-04-11
CN107670034A (zh) 2018-02-09
JP6421140B2 (ja) 2018-11-07
RU2769949C2 (ru) 2022-04-11
CN114099667B (zh) 2025-10-21
CN114099668B (zh) 2025-10-17
EP2606068B1 (en) 2017-09-27
PL2606068T3 (pl) 2018-03-30
CA2808744A1 (en) 2012-02-23
US10525129B2 (en) 2020-01-07

Similar Documents

Publication Publication Date Title
GB201013989D0 (en) Biological materials and methods of using the same
IL249669B (en) Converted 5-fluoro-h1-pyrazolopyridines and their use
SI2516468T1 (sl) Protitelesa proti flt3 in postopki uporabe istih
GB201011771D0 (en) Biological material and particular uses thereof
ZA201300612B (en) Novel bacteria and methods of use thereof
PL2539326T3 (pl) Połączone bis-arylem arylotriazolony i ich zastosowanie
PL2946791T3 (pl) Przeciwciała anty-CD277 i ich zastosowania
IL215795A0 (en) Anti-il-17f antibodies and methods of use thereof
ZA201208173B (en) Peptices and their use
GB2477597B (en) Disinfectant materials and methods
GB0904825D0 (en) Biological materials and uses thereof
ZA201303773B (en) Compounds and their use
ZA201300174B (en) Anti-neuropilin antibodies and methods of use
EP2525651A4 (en) NEW CENTROMERE AND METHOD FOR THEIR USE
PL2406280T3 (pl) Materiały biologiczne oraz ich zastosowania
EP2649217A4 (en) ARTICLE AND METHOD FOR ITS MANUFACTURE AND USE
GB201020357D0 (en) Compounds and methods of making the same
GB0922143D0 (en) Biological materials and uses thereof
GB201009307D0 (en) Biological materials and uses thereof
GB201112000D0 (en) Biological materials and uses thereof
GB201011770D0 (en) Biological material and there uses thereof
GB201019361D0 (en) Biosensor and uses thereof
GB201005511D0 (en) Compounds and their use
GB201000305D0 (en) Compounds and their use
GB201017822D0 (en) Compounds and their use

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)