GB201002730D0 - Product - Google Patents

Product

Info

Publication number
GB201002730D0
GB201002730D0 GBGB1002730.8A GB201002730A GB201002730D0 GB 201002730 D0 GB201002730 D0 GB 201002730D0 GB 201002730 A GB201002730 A GB 201002730A GB 201002730 D0 GB201002730 D0 GB 201002730D0
Authority
GB
United Kingdom
Prior art keywords
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1002730.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitetet i Oslo
Original Assignee
Universitetet i Oslo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitetet i Oslo filed Critical Universitetet i Oslo
Priority to GBGB1002730.8A priority Critical patent/GB201002730D0/en
Publication of GB201002730D0 publication Critical patent/GB201002730D0/en
Priority to KR1020127024287A priority patent/KR101647176B1/ko
Priority to PL11730044T priority patent/PL2536746T3/pl
Priority to DK11730044.2T priority patent/DK2536746T3/en
Priority to ES11730044T priority patent/ES2572388T3/es
Priority to CN201180011237.4A priority patent/CN102947330B/zh
Priority to PCT/GB2011/050325 priority patent/WO2011101681A2/en
Priority to RU2012138302/10A priority patent/RU2604813C2/ru
Priority to US13/579,887 priority patent/US8828379B2/en
Priority to HRP20160475TT priority patent/HRP20160475T1/hr
Priority to HUE11730044A priority patent/HUE027952T2/en
Priority to RS20160323A priority patent/RS54744B1/sr
Priority to CA2789492A priority patent/CA2789492C/en
Priority to EP11730044.2A priority patent/EP2536746B1/en
Priority to JP2012553409A priority patent/JP5537675B2/ja
Priority to SI201130815A priority patent/SI2536746T1/sl
Priority to AU2011217027A priority patent/AU2011217027B2/en
Priority to US14/331,014 priority patent/US9056920B2/en
Priority to CY20161100397T priority patent/CY1117697T1/el
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
GBGB1002730.8A 2010-02-18 2010-02-18 Product Ceased GB201002730D0 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
GBGB1002730.8A GB201002730D0 (en) 2010-02-18 2010-02-18 Product
AU2011217027A AU2011217027B2 (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble MHC class II heterodimers
US13/579,887 US8828379B2 (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble MHC class II heterodimers
HUE11730044A HUE027952T2 (en) 2010-02-18 2011-02-18 Disulfide bonded, functional, soluble, MCH class II heterodimers
DK11730044.2T DK2536746T3 (en) 2010-02-18 2011-02-18 Disulphide-bond stabilized functional soluble MHC class II heterodimeric
ES11730044T ES2572388T3 (es) 2010-02-18 2011-02-18 Heterodímeros del MHC de clase II solubles funcionales estabilizados por enlaces disulfuro
CN201180011237.4A CN102947330B (zh) 2010-02-18 2011-02-18 二硫键稳定的功能性可溶mhc ii类异二聚体
PCT/GB2011/050325 WO2011101681A2 (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble mhc class ii heterodimers
RU2012138302/10A RU2604813C2 (ru) 2010-02-18 2011-02-18 Функциональные растворимые гетеродимеры мнс ii класса со стабилизирующей дисульфидной связью
KR1020127024287A KR101647176B1 (ko) 2010-02-18 2011-02-18 디설파이드 결합으로 안정화된 기능성 가용성 mhc클래스 ⅱ 헤테로다이머류
HRP20160475TT HRP20160475T1 (hr) 2010-02-18 2011-02-18 Disulfidnom vezom stabilizirani funkcionalni topivi heterodimeri mhc klase ii
PL11730044T PL2536746T3 (pl) 2010-02-18 2011-02-18 Stabilizowane wiązaniem disulfidowym funkcjonalne rozpuszczalne heterodimery mhc klasy ii
RS20160323A RS54744B1 (sr) 2010-02-18 2011-02-18 Rastvorljivi funkcionalni heterodimeri mhc klase ii stabilizovani disulfidnom vezom
CA2789492A CA2789492C (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble mhc class ii heterodimers
EP11730044.2A EP2536746B1 (en) 2010-02-18 2011-02-18 Disulphide bond-stabilized functional soluble mhc class ii heterodimers
JP2012553409A JP5537675B2 (ja) 2010-02-18 2011-02-18 ジスルフィド結合により安定化された機能的可溶性mhcクラスiiヘテロ二量体
SI201130815A SI2536746T1 (sl) 2010-02-18 2011-02-18 Z disulfidno vezjo-stabilizirani funkcionalni topni heterodimeri mhc razreda ii
US14/331,014 US9056920B2 (en) 2010-02-18 2014-07-14 Disulphide bond-stabilized functional soluble MHC class II heterodimers
CY20161100397T CY1117697T1 (el) 2010-02-18 2016-05-11 Σταθεροποιημενα απο δεσμους δισουλφιδιων λειτουργικα ευδιαλυτα ετεροδιμερη toy mhc ταξης ii

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1002730.8A GB201002730D0 (en) 2010-02-18 2010-02-18 Product

Publications (1)

Publication Number Publication Date
GB201002730D0 true GB201002730D0 (en) 2010-04-07

Family

ID=42113985

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1002730.8A Ceased GB201002730D0 (en) 2010-02-18 2010-02-18 Product

Country Status (18)

Country Link
US (2) US8828379B2 (https=)
EP (1) EP2536746B1 (https=)
JP (1) JP5537675B2 (https=)
KR (1) KR101647176B1 (https=)
CN (1) CN102947330B (https=)
AU (1) AU2011217027B2 (https=)
CA (1) CA2789492C (https=)
CY (1) CY1117697T1 (https=)
DK (1) DK2536746T3 (https=)
ES (1) ES2572388T3 (https=)
GB (1) GB201002730D0 (https=)
HR (1) HRP20160475T1 (https=)
HU (1) HUE027952T2 (https=)
PL (1) PL2536746T3 (https=)
RS (1) RS54744B1 (https=)
RU (1) RU2604813C2 (https=)
SI (1) SI2536746T1 (https=)
WO (1) WO2011101681A2 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
ES3011307T3 (en) 2012-02-23 2025-04-07 Juno Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
EP4592400A3 (en) 2012-10-17 2025-10-29 10x Genomics Sweden AB Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
JP6748061B2 (ja) * 2014-07-09 2020-08-26 ルピン・リミテッド 二重シストロン細菌発現システム
US11059880B2 (en) 2015-06-30 2021-07-13 Arizona Board Of Regents On Behalf Of The University Of Arizona Redirected cells with MHC chimeric receptors and methods of use in immunotherapy
US12577289B2 (en) 2015-06-30 2026-03-17 Arizona Board Of Regents On Behalf Of The University Of Arizona Surrogate co-receptors for t cells and methods of use
MX2018004875A (es) 2015-10-22 2018-08-01 Juno Therapeutics Gmbh Metodos para cultivar celulas y kits y aparatos para ello.
EP3365453A2 (en) 2015-10-22 2018-08-29 Juno Therapeutics GmbH Methods, kits, agents and apparatuses for transduction
US10294454B2 (en) 2016-08-24 2019-05-21 General Electric Company Methods and kits for cell activation
US20180127481A1 (en) * 2016-11-09 2018-05-10 Uti Limited Partnership RECOMBINANT pMHC CLASS II MOLECULES
JP7339160B2 (ja) 2017-04-27 2023-09-05 ジュノ セラピューティクス ゲーエムベーハー オリゴマー粒子試薬およびその使用方法
DE102018122546B3 (de) 2018-09-14 2019-12-05 Immatics Biotechnologies Gmbh Verfahren zum Hochdurchsatz-Peptid-MHC-Affinitätsscreening für TCR-Liganden
EP4345453B1 (en) * 2018-09-28 2025-11-12 10X Genomics, Inc. High throughput epitope identification and t cell receptor specificity determination using loadable detection molecules
SG11202104355SA (en) 2018-10-31 2021-05-28 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
EP3719033A1 (en) * 2019-04-02 2020-10-07 imusyn GmbH & Co. KG Stabilized mhc i
WO2021035049A1 (en) * 2019-08-21 2021-02-25 Uti Limited Partnership Improved recombinant pmhc molecules
EP4028412A2 (en) * 2019-09-13 2022-07-20 The Regents of The University of California Systems and methods for the preparation of peptide-mhc-i complexes with native glycan modifications
US20220409732A1 (en) * 2019-12-02 2022-12-29 Regeneron Pharmaceuticals, Inc. Peptide-mhc ii protein constructs and uses thereof
TW202144389A (zh) 2020-02-14 2021-12-01 美商健生生物科技公司 在多發性骨髓瘤中表現之新抗原及其用途
TW202144388A (zh) 2020-02-14 2021-12-01 美商健生生物科技公司 在卵巢癌中表現之新抗原及其用途
DE102020109447A1 (de) 2020-04-03 2021-10-07 Jacobs University Bremen Ggmbh Synthetisches mhc-klasse-ii-protein
US12534510B2 (en) 2020-04-16 2026-01-27 The Regents Of The University Of California Peptide-receptive MHC-I complex compositions and methods
EP4175664A2 (en) 2020-07-06 2023-05-10 Janssen Biotech, Inc. Prostate neoantigens and their uses
CN118813436A (zh) * 2023-07-24 2024-10-22 佳吾益(北京)科技有限公司 展示单mhc等位基因功能蛋白的工程化细胞
CN119220425A (zh) * 2023-07-28 2024-12-31 佳吾益(北京)科技有限公司 发现mhc新抗原肽表位的工程化细胞
WO2025137580A1 (en) * 2023-12-22 2025-06-26 Antiger Therapeutics, Inc. Class ii hla with inter-chain disulfide bond

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Publication number Priority date Publication date Assignee Title
WO1990010457A1 (en) 1989-03-14 1990-09-20 New York University Method of treating hiv infections using immunotoxins
JP2000516470A (ja) * 1996-08-16 2000-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ 可溶性一価および多価mhcクラスii融合タンパク質およびそれらの使用
CA2302779C (en) * 1997-09-16 2010-02-02 Oregon Health Sciences University Recombinant mhc molecules useful for manipulation of antigen-specific t-cells
WO1999060120A2 (en) * 1998-05-19 1999-11-25 Avidex Limited Soluble t cell receptor
RU2303264C2 (ru) * 2001-02-19 2007-07-20 Мерк Патент Гмбх Способ идентификации эпитопов т-клеток и его применение для получения молекул со сниженной иммуногенностью
GB2392158B (en) * 2002-08-21 2005-02-16 Proimmune Ltd Chimeric MHC protein and oligomer thereof
US8377447B2 (en) * 2003-09-05 2013-02-19 Oregon Health & Science University Monomeric recombinant MHC molecules useful for manipulation of antigen-specific T cells
CA2638892A1 (en) 2005-03-18 2006-09-28 Oregon Health & Science University Recombinant mhc molecules useful for manipulation of antigen-specific t cells
ES2709176T3 (es) 2006-08-11 2019-04-15 Life Sciences Res Partners Vzw Péptidos inmunogénicos y su uso en trastornos inmunitarios
JP5154564B2 (ja) * 2006-12-01 2013-02-27 カール・ツァイス・エスエムティー・ゲーエムベーハー 像収差を低減するための交換可能で操作可能な補正構成を有する光学システム
ES2445152T3 (es) 2007-08-20 2014-02-28 Nextera As Presentación en fagos de pVII

Also Published As

Publication number Publication date
KR20130009782A (ko) 2013-01-23
WO2011101681A2 (en) 2011-08-25
JP5537675B2 (ja) 2014-07-02
AU2011217027B2 (en) 2015-02-05
CA2789492C (en) 2017-04-18
ES2572388T3 (es) 2016-05-31
KR101647176B1 (ko) 2016-08-09
US8828379B2 (en) 2014-09-09
PL2536746T3 (pl) 2016-08-31
RS54744B1 (sr) 2016-10-31
SI2536746T1 (sl) 2016-09-30
RU2012138302A (ru) 2014-03-27
RU2604813C2 (ru) 2016-12-10
WO2011101681A3 (en) 2011-12-08
US20130171668A1 (en) 2013-07-04
US9056920B2 (en) 2015-06-16
JP2013519721A (ja) 2013-05-30
HUE027952T2 (en) 2016-11-28
EP2536746A2 (en) 2012-12-26
US20140349315A1 (en) 2014-11-27
HRP20160475T1 (hr) 2016-06-03
CN102947330B (zh) 2015-09-16
CY1117697T1 (el) 2017-05-17
CA2789492A1 (en) 2011-08-25
AU2011217027A1 (en) 2012-09-06
EP2536746B1 (en) 2016-04-20
CN102947330A (zh) 2013-02-27
DK2536746T3 (en) 2016-05-30

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Legal Events

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AT Applications terminated before publication under section 16(1)