GB1589792A - F3-phenoxy-n-substituted morphinan derivatives their manufacture and pharmaceutical preparations containing them - Google Patents

F3-phenoxy-n-substituted morphinan derivatives their manufacture and pharmaceutical preparations containing them Download PDF

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Publication number
GB1589792A
GB1589792A GB50495/77A GB5049577A GB1589792A GB 1589792 A GB1589792 A GB 1589792A GB 50495/77 A GB50495/77 A GB 50495/77A GB 5049577 A GB5049577 A GB 5049577A GB 1589792 A GB1589792 A GB 1589792A
Authority
GB
United Kingdom
Prior art keywords
phenoxy
group
methylmorphinan
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB50495/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/811,233 external-priority patent/US4113729A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1589792A publication Critical patent/GB1589792A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
GB50495/77A 1976-12-06 1977-12-05 F3-phenoxy-n-substituted morphinan derivatives their manufacture and pharmaceutical preparations containing them Expired GB1589792A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74802276A 1976-12-06 1976-12-06
US05/811,233 US4113729A (en) 1976-12-06 1977-06-29 3-Phenoxymorphinans and derivatives thereof

Publications (1)

Publication Number Publication Date
GB1589792A true GB1589792A (en) 1981-05-20

Family

ID=27114858

Family Applications (1)

Application Number Title Priority Date Filing Date
GB50495/77A Expired GB1589792A (en) 1976-12-06 1977-12-05 F3-phenoxy-n-substituted morphinan derivatives their manufacture and pharmaceutical preparations containing them

Country Status (22)

Country Link
JP (1) JPS5392776A (xx)
AR (1) AR219510A1 (xx)
AT (1) AT364826B (xx)
AU (1) AU514827B2 (xx)
CA (1) CA1088935A (xx)
DE (1) DE2754062A1 (xx)
DK (1) DK540977A (xx)
ES (3) ES464751A1 (xx)
FI (1) FI773636A (xx)
FR (1) FR2372808A1 (xx)
GB (1) GB1589792A (xx)
HU (1) HU177640B (xx)
IE (1) IE46003B1 (xx)
IL (1) IL53532A (xx)
IT (1) IT1143727B (xx)
LU (1) LU78638A1 (xx)
MC (1) MC1172A1 (xx)
NL (1) NL7713432A (xx)
NO (1) NO774155L (xx)
NZ (1) NZ185860A (xx)
PT (1) PT67363B (xx)
SE (1) SE7713779L (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247697A (en) * 1979-09-10 1981-01-27 Hoffmann-La Roche Inc. 3-Phenoxy morphinans and their derivatives
TW264473B (xx) * 1993-01-06 1995-12-01 Hoffmann La Roche

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH543514A (de) * 1967-08-25 1973-10-31 Hoffmann La Roche Verfahren zur Herstellung von Morphinanderivaten
JPS493961B1 (xx) * 1969-06-24 1974-01-29

Also Published As

Publication number Publication date
FR2372808B1 (xx) 1981-07-10
DK540977A (da) 1978-06-07
PT67363A (en) 1978-01-01
HU177640B (en) 1981-11-28
ES472573A1 (es) 1979-02-16
IL53532A0 (en) 1978-03-10
AT364826B (de) 1981-11-25
AU514827B2 (en) 1981-02-26
FI773636A (fi) 1978-06-07
ES464751A1 (es) 1978-12-16
LU78638A1 (xx) 1979-02-02
AR219510A1 (es) 1980-08-29
SE7713779L (sv) 1978-06-07
ES472572A1 (es) 1979-02-16
PT67363B (en) 1979-12-17
NL7713432A (nl) 1978-06-08
JPS5392776A (en) 1978-08-15
IE46003L (en) 1978-06-06
IE46003B1 (en) 1983-01-26
NO774155L (no) 1978-06-07
NZ185860A (en) 1980-10-24
ATA869277A (de) 1981-04-15
IT1143727B (it) 1986-10-22
CA1088935A (en) 1980-11-04
AU3126477A (en) 1979-06-14
DE2754062A1 (de) 1978-06-08
FR2372808A1 (fr) 1978-06-30
MC1172A1 (fr) 1978-09-25
IL53532A (en) 1981-09-13

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
429A Application made for amendment of specification (sect. 29/1949)
429H Application (made) for amendment of specification now open to opposition (sect. 29/1949)
429D Case decided by the comptroller ** specification amended (sect. 29/1949)
SP Amendment (slips) printed
PCNP Patent ceased through non-payment of renewal fee