CA1088935A - Levo-rotary 3-phenoxy morphinan derivatives - Google Patents

Levo-rotary 3-phenoxy morphinan derivatives

Info

Publication number
CA1088935A
CA1088935A CA292,433A CA292433A CA1088935A CA 1088935 A CA1088935 A CA 1088935A CA 292433 A CA292433 A CA 292433A CA 1088935 A CA1088935 A CA 1088935A
Authority
CA
Canada
Prior art keywords
compound
phenoxy
chemical equivalent
obvious chemical
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA292,433A
Other languages
English (en)
French (fr)
Inventor
Ernest Mohacsi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/811,233 external-priority patent/US4113729A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1088935A publication Critical patent/CA1088935A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA292,433A 1976-12-06 1977-12-05 Levo-rotary 3-phenoxy morphinan derivatives Expired CA1088935A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74802276A 1976-12-06 1976-12-06
US748,022 1976-12-06
US05/811,233 US4113729A (en) 1976-12-06 1977-06-29 3-Phenoxymorphinans and derivatives thereof
US811,233 1977-06-29

Publications (1)

Publication Number Publication Date
CA1088935A true CA1088935A (en) 1980-11-04

Family

ID=27114858

Family Applications (1)

Application Number Title Priority Date Filing Date
CA292,433A Expired CA1088935A (en) 1976-12-06 1977-12-05 Levo-rotary 3-phenoxy morphinan derivatives

Country Status (22)

Country Link
JP (1) JPS5392776A (xx)
AR (1) AR219510A1 (xx)
AT (1) AT364826B (xx)
AU (1) AU514827B2 (xx)
CA (1) CA1088935A (xx)
DE (1) DE2754062A1 (xx)
DK (1) DK540977A (xx)
ES (3) ES464751A1 (xx)
FI (1) FI773636A (xx)
FR (1) FR2372808A1 (xx)
GB (1) GB1589792A (xx)
HU (1) HU177640B (xx)
IE (1) IE46003B1 (xx)
IL (1) IL53532A (xx)
IT (1) IT1143727B (xx)
LU (1) LU78638A1 (xx)
MC (1) MC1172A1 (xx)
NL (1) NL7713432A (xx)
NO (1) NO774155L (xx)
NZ (1) NZ185860A (xx)
PT (1) PT67363B (xx)
SE (1) SE7713779L (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247697A (en) * 1979-09-10 1981-01-27 Hoffmann-La Roche Inc. 3-Phenoxy morphinans and their derivatives
TW264473B (xx) * 1993-01-06 1995-12-01 Hoffmann La Roche

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH560194A5 (xx) * 1967-08-25 1975-03-27 Hoffmann La Roche
JPS493961B1 (xx) * 1969-06-24 1974-01-29

Also Published As

Publication number Publication date
NO774155L (no) 1978-06-07
FI773636A (fi) 1978-06-07
PT67363B (en) 1979-12-17
PT67363A (en) 1978-01-01
AR219510A1 (es) 1980-08-29
SE7713779L (sv) 1978-06-07
FR2372808B1 (xx) 1981-07-10
JPS5392776A (en) 1978-08-15
IL53532A0 (en) 1978-03-10
ATA869277A (de) 1981-04-15
ES464751A1 (es) 1978-12-16
DK540977A (da) 1978-06-07
AU514827B2 (en) 1981-02-26
ES472572A1 (es) 1979-02-16
AT364826B (de) 1981-11-25
IE46003L (en) 1978-06-06
FR2372808A1 (fr) 1978-06-30
AU3126477A (en) 1979-06-14
GB1589792A (en) 1981-05-20
MC1172A1 (fr) 1978-09-25
DE2754062A1 (de) 1978-06-08
NZ185860A (en) 1980-10-24
IE46003B1 (en) 1983-01-26
IT1143727B (it) 1986-10-22
ES472573A1 (es) 1979-02-16
LU78638A1 (xx) 1979-02-02
HU177640B (en) 1981-11-28
IL53532A (en) 1981-09-13
NL7713432A (nl) 1978-06-08

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Legal Events

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