ES464751A1 - Un procedimiento para la preparacion de derivados de morfi- nano 3-3fenoxi-n-sustituidos levogiros. - Google Patents
Un procedimiento para la preparacion de derivados de morfi- nano 3-3fenoxi-n-sustituidos levogiros.Info
- Publication number
- ES464751A1 ES464751A1 ES464751A ES464751A ES464751A1 ES 464751 A1 ES464751 A1 ES 464751A1 ES 464751 A ES464751 A ES 464751A ES 464751 A ES464751 A ES 464751A ES 464751 A1 ES464751 A1 ES 464751A1
- Authority
- ES
- Spain
- Prior art keywords
- phenoxy
- manufacture
- pharmaceutical preparations
- preparations containing
- morphinan derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
Un procedimiento para la preparación de derivados de morfinano 3-fenoxi-N-substituidos levogiros, de la fórmula general **(Fórmula)** En donde R es halógeno, nitro, alquilo inferior, alcoxilo inferior, hidroxilo o hidrógeno; R2 es heteroaromático, aromático o ciclo-alquilo inferior; p es un número entero comprendido entre 0 y 3 y n es un número entero comprendido entre 1 y 5 y sus sales aceptables en farmacia.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74802276A | 1976-12-06 | 1976-12-06 | |
| US05/811,233 US4113729A (en) | 1976-12-06 | 1977-06-29 | 3-Phenoxymorphinans and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES464751A1 true ES464751A1 (es) | 1978-12-16 |
Family
ID=27114858
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES464751A Expired ES464751A1 (es) | 1976-12-06 | 1977-12-05 | Un procedimiento para la preparacion de derivados de morfi- nano 3-3fenoxi-n-sustituidos levogiros. |
| ES472573A Expired ES472573A1 (es) | 1976-12-06 | 1978-08-16 | Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros |
| ES472572A Expired ES472572A1 (es) | 1976-12-06 | 1978-08-16 | Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES472573A Expired ES472573A1 (es) | 1976-12-06 | 1978-08-16 | Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros |
| ES472572A Expired ES472572A1 (es) | 1976-12-06 | 1978-08-16 | Un procedimiento para la preparacion de derivados de morfi- nano 3-fenoxi-n-sustituidos levogiros |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5392776A (es) |
| AR (1) | AR219510A1 (es) |
| AT (1) | AT364826B (es) |
| AU (1) | AU514827B2 (es) |
| CA (1) | CA1088935A (es) |
| DE (1) | DE2754062A1 (es) |
| DK (1) | DK540977A (es) |
| ES (3) | ES464751A1 (es) |
| FI (1) | FI773636A7 (es) |
| FR (1) | FR2372808A1 (es) |
| GB (1) | GB1589792A (es) |
| HU (1) | HU177640B (es) |
| IE (1) | IE46003B1 (es) |
| IL (1) | IL53532A (es) |
| IT (1) | IT1143727B (es) |
| LU (1) | LU78638A1 (es) |
| MC (1) | MC1172A1 (es) |
| NL (1) | NL7713432A (es) |
| NO (1) | NO774155L (es) |
| NZ (1) | NZ185860A (es) |
| PT (1) | PT67363B (es) |
| SE (1) | SE7713779L (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4247697A (en) * | 1979-09-10 | 1981-01-27 | Hoffmann-La Roche Inc. | 3-Phenoxy morphinans and their derivatives |
| TW264473B (es) * | 1993-01-06 | 1995-12-01 | Hoffmann La Roche |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH543514A (de) * | 1967-08-25 | 1973-10-31 | Hoffmann La Roche | Verfahren zur Herstellung von Morphinanderivaten |
| JPS493961B1 (es) * | 1969-06-24 | 1974-01-29 |
-
1977
- 1977-11-30 FI FI773636A patent/FI773636A7/fi not_active Application Discontinuation
- 1977-12-05 ES ES464751A patent/ES464751A1/es not_active Expired
- 1977-12-05 IE IE2468/77A patent/IE46003B1/en unknown
- 1977-12-05 GB GB50495/77A patent/GB1589792A/en not_active Expired
- 1977-12-05 NL NL7713432A patent/NL7713432A/xx not_active Application Discontinuation
- 1977-12-05 LU LU7778638A patent/LU78638A1/xx unknown
- 1977-12-05 JP JP14520377A patent/JPS5392776A/ja active Pending
- 1977-12-05 MC MC771272A patent/MC1172A1/fr unknown
- 1977-12-05 NZ NZ185860A patent/NZ185860A/xx unknown
- 1977-12-05 IL IL53532A patent/IL53532A/xx unknown
- 1977-12-05 DK DK540977A patent/DK540977A/da unknown
- 1977-12-05 AT AT0869277A patent/AT364826B/de not_active IP Right Cessation
- 1977-12-05 CA CA292,433A patent/CA1088935A/en not_active Expired
- 1977-12-05 PT PT67363A patent/PT67363B/pt unknown
- 1977-12-05 SE SE7713779A patent/SE7713779L/xx not_active Application Discontinuation
- 1977-12-05 NO NO774155A patent/NO774155L/no unknown
- 1977-12-05 HU HU77HO2029A patent/HU177640B/hu unknown
- 1977-12-05 DE DE19772754062 patent/DE2754062A1/de not_active Withdrawn
- 1977-12-06 FR FR7736745A patent/FR2372808A1/fr active Granted
- 1977-12-06 AU AU31264/77A patent/AU514827B2/en not_active Expired
- 1977-12-06 AR AR270265A patent/AR219510A1/es active
- 1977-12-06 IT IT30510/77A patent/IT1143727B/it active
-
1978
- 1978-08-16 ES ES472573A patent/ES472573A1/es not_active Expired
- 1978-08-16 ES ES472572A patent/ES472572A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK540977A (da) | 1978-06-07 |
| AU3126477A (en) | 1979-06-14 |
| AU514827B2 (en) | 1981-02-26 |
| MC1172A1 (fr) | 1978-09-25 |
| AT364826B (de) | 1981-11-25 |
| HU177640B (en) | 1981-11-28 |
| AR219510A1 (es) | 1980-08-29 |
| PT67363A (en) | 1978-01-01 |
| FI773636A7 (fi) | 1978-06-07 |
| IL53532A0 (en) | 1978-03-10 |
| NZ185860A (en) | 1980-10-24 |
| JPS5392776A (en) | 1978-08-15 |
| DE2754062A1 (de) | 1978-06-08 |
| NO774155L (no) | 1978-06-07 |
| FR2372808A1 (fr) | 1978-06-30 |
| ATA869277A (de) | 1981-04-15 |
| NL7713432A (nl) | 1978-06-08 |
| IE46003B1 (en) | 1983-01-26 |
| IE46003L (en) | 1978-06-06 |
| SE7713779L (sv) | 1978-06-07 |
| ES472573A1 (es) | 1979-02-16 |
| FR2372808B1 (es) | 1981-07-10 |
| CA1088935A (en) | 1980-11-04 |
| ES472572A1 (es) | 1979-02-16 |
| PT67363B (en) | 1979-12-17 |
| IT1143727B (it) | 1986-10-22 |
| LU78638A1 (es) | 1979-02-02 |
| GB1589792A (en) | 1981-05-20 |
| IL53532A (en) | 1981-09-13 |
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