GB1585124A - Clavulanic acid derivatives - Google Patents

Clavulanic acid derivatives Download PDF

Info

Publication number
GB1585124A
GB1585124A GB23268/76A GB2326876A GB1585124A GB 1585124 A GB1585124 A GB 1585124A GB 23268/76 A GB23268/76 A GB 23268/76A GB 2326876 A GB2326876 A GB 2326876A GB 1585124 A GB1585124 A GB 1585124A
Authority
GB
United Kingdom
Prior art keywords
group
compound
formula
clavam
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB23268/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Priority to GB23268/76A priority Critical patent/GB1585124A/en
Priority to DK247877A priority patent/DK247877A/da
Priority to BE178181A priority patent/BE855375A/xx
Priority to FI771772A priority patent/FI771772A/fi
Priority to SE7706518A priority patent/SE7706518L/xx
Priority to NL7706119A priority patent/NL7706119A/xx
Priority to ZA00773348A priority patent/ZA773348B/xx
Priority to DE19772725203 priority patent/DE2725203A1/de
Priority to FR7717099A priority patent/FR2353556A1/fr
Priority to IL52244A priority patent/IL52244A0/xx
Priority to JP6568077A priority patent/JPS5321193A/ja
Priority to AT395477A priority patent/AT356814B/de
Priority to AU25804/77A priority patent/AU517897B2/en
Priority to CH687277A priority patent/CH628055A5/de
Priority to ES459479A priority patent/ES459479A1/es
Priority to ES470333A priority patent/ES470333A1/es
Publication of GB1585124A publication Critical patent/GB1585124A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GB23268/76A 1976-06-04 1976-06-04 Clavulanic acid derivatives Expired GB1585124A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
GB23268/76A GB1585124A (en) 1976-06-04 1976-06-04 Clavulanic acid derivatives
DK247877A DK247877A (da) 1976-06-04 1977-06-03 Fremgangsmade til fremstilling af klavamforbindelser
BE178181A BE855375A (fr) 1976-06-04 1977-06-03 Derives du type amino et azido de l'acide clavulanique.
FI771772A FI771772A (ja) 1976-06-04 1977-06-03
SE7706518A SE7706518L (sv) 1976-06-04 1977-06-03 Forfarande for framstellning av antibiotika
NL7706119A NL7706119A (nl) 1976-06-04 1977-06-03 Werkwijzen voor de bereiding en toepassing van nieuwe antibiotica.
ZA00773348A ZA773348B (en) 1976-06-04 1977-06-03 Azido-and amino-clavulanic acid and derivatives
DE19772725203 DE2725203A1 (de) 1976-06-04 1977-06-03 Neue clavamsaeurederivate und verfahren zu deren herstellung
FR7717099A FR2353556A1 (fr) 1976-06-04 1977-06-03 Derives de l'acide clavulanique, leur procede de preparation et leur application en therapeutique
IL52244A IL52244A0 (en) 1976-06-04 1977-06-03 Clavam-3-carboxylic acid derivatives
JP6568077A JPS5321193A (en) 1976-06-04 1977-06-03 Production of novel antibiotic
AT395477A AT356814B (de) 1976-06-04 1977-06-03 Verfahren zur herstellung von neuen clavulan- saeurederivaten
AU25804/77A AU517897B2 (en) 1976-06-04 1977-06-03 Clavulanic acid analogues
CH687277A CH628055A5 (en) 1976-06-04 1977-06-03 Process for the preparation of clavamic acid derivatives
ES459479A ES459479A1 (es) 1976-06-04 1977-06-03 Un procedimiento para la preparacion de nuevos derivados de acido clavulanico.
ES470333A ES470333A1 (es) 1976-06-04 1978-05-30 Un procedimiento para la preparacion de nuevos derivados de acido clavulanico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB23268/76A GB1585124A (en) 1976-06-04 1976-06-04 Clavulanic acid derivatives

Publications (1)

Publication Number Publication Date
GB1585124A true GB1585124A (en) 1981-02-25

Family

ID=10192928

Family Applications (1)

Application Number Title Priority Date Filing Date
GB23268/76A Expired GB1585124A (en) 1976-06-04 1976-06-04 Clavulanic acid derivatives

Country Status (15)

Country Link
JP (1) JPS5321193A (ja)
AT (1) AT356814B (ja)
AU (1) AU517897B2 (ja)
BE (1) BE855375A (ja)
CH (1) CH628055A5 (ja)
DE (1) DE2725203A1 (ja)
DK (1) DK247877A (ja)
ES (2) ES459479A1 (ja)
FI (1) FI771772A (ja)
FR (1) FR2353556A1 (ja)
GB (1) GB1585124A (ja)
IL (1) IL52244A0 (ja)
NL (1) NL7706119A (ja)
SE (1) SE7706518L (ja)
ZA (1) ZA773348B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068609A1 (en) * 1981-06-11 1983-01-05 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and their use
EP0213914A2 (en) * 1985-08-29 1987-03-11 Beecham Group Plc Clavam derivatives, preparation and intermediates therefor

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1604822A (en) * 1977-04-22 1981-12-16 Beecham Group Ltd N-monosubstituted-9-amino-9-deoxyclavulanic acid derivative
FR2388814A1 (fr) * 1977-04-27 1978-11-24 Beecham Group Ltd Nouveaux derives de l'acide clavulanique, utilisables comme medicament
JPS54117459A (en) * 1978-01-20 1979-09-12 Glaxo Group Ltd Novel lactam compound
DE3066511D1 (en) * 1979-10-26 1984-03-15 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and pharmaceutical compositions containing them
EP0053893B1 (en) * 1980-12-09 1985-03-20 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
GB9518917D0 (en) * 1995-09-15 1995-11-15 Smithkline Beecham Plc Compounds

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068609A1 (en) * 1981-06-11 1983-01-05 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and their use
EP0213914A2 (en) * 1985-08-29 1987-03-11 Beecham Group Plc Clavam derivatives, preparation and intermediates therefor
EP0213914A3 (en) * 1985-08-29 1988-07-27 Beecham Group Plc Clavam derivatives, preparation and intermediates therefor
US4795809A (en) * 1985-08-29 1989-01-03 Beecham Group Plc Novel clavam derivatives and methods of making same

Also Published As

Publication number Publication date
IL52244A0 (en) 1977-08-31
CH628055A5 (en) 1982-02-15
JPS6135994B2 (ja) 1986-08-15
BE855375A (fr) 1977-12-05
DE2725203A1 (de) 1977-12-22
ES459479A1 (es) 1978-11-16
NL7706119A (nl) 1977-12-06
FR2353556B1 (ja) 1980-04-04
FI771772A (ja) 1977-12-05
AU517897B2 (en) 1981-09-03
DK247877A (da) 1977-12-05
AU2580477A (en) 1978-12-07
AT356814B (de) 1980-05-27
JPS5321193A (en) 1978-02-27
FR2353556A1 (fr) 1977-12-30
ES470333A1 (es) 1979-01-01
ATA395477A (de) 1979-10-15
ZA773348B (en) 1978-06-28
SE7706518L (sv) 1978-01-23

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee