GB1575310A - Piperidine derivatives - Google Patents

Piperidine derivatives Download PDF

Info

Publication number
GB1575310A
GB1575310A GB4773876A GB4773876A GB1575310A GB 1575310 A GB1575310 A GB 1575310A GB 4773876 A GB4773876 A GB 4773876A GB 4773876 A GB4773876 A GB 4773876A GB 1575310 A GB1575310 A GB 1575310A
Authority
GB
United Kingdom
Prior art keywords
group
amino
chlorobenzamide
general formula
propargyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4773876A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anphar SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Priority to GB4773876A priority Critical patent/GB1575310A/en
Priority to ES464148A priority patent/ES464148A1/es
Priority to ES464149A priority patent/ES464149A1/es
Priority to FR7735106A priority patent/FR2370731A1/fr
Priority to DE19772751181 priority patent/DE2751181A1/de
Priority to JP13773577A priority patent/JPS5387364A/ja
Publication of GB1575310A publication Critical patent/GB1575310A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB4773876A 1976-11-16 1976-11-16 Piperidine derivatives Expired GB1575310A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB4773876A GB1575310A (en) 1976-11-16 1976-11-16 Piperidine derivatives
ES464148A ES464148A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de nuevos derivados de la pipe-ridina.
ES464149A ES464149A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de nuevos derivados de la pipe-ridina.
FR7735106A FR2370731A1 (fr) 1976-11-16 1977-11-15 Nouveaux derives de la piperidine polysubstitues, leurs procedes de preparation et leur application pharmaceutique
DE19772751181 DE2751181A1 (de) 1976-11-16 1977-11-16 Neue therapeutika auf piperidinbasis
JP13773577A JPS5387364A (en) 1976-11-16 1977-11-16 Piperidine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4773876A GB1575310A (en) 1976-11-16 1976-11-16 Piperidine derivatives

Publications (1)

Publication Number Publication Date
GB1575310A true GB1575310A (en) 1980-09-17

Family

ID=10446083

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4773876A Expired GB1575310A (en) 1976-11-16 1976-11-16 Piperidine derivatives

Country Status (5)

Country Link
JP (1) JPS5387364A (enExample)
DE (1) DE2751181A1 (enExample)
ES (2) ES464148A1 (enExample)
FR (1) FR2370731A1 (enExample)
GB (1) GB1575310A (enExample)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057525A (en) * 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
US5137896A (en) * 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
WO2001036385A1 (en) * 1999-11-17 2001-05-25 Kissei Pharmaceutical Co., Ltd. Hydroxyethoxybenzamide derivatives and drugs containing the same
WO2004046110A1 (ja) * 2002-11-15 2004-06-03 Yamanouchi Pharmaceutical Co., Ltd. メラニン凝集ホルモン受容体拮抗剤
US7285564B2 (en) 2002-10-30 2007-10-23 Theravance, Inc. Substituted 4-amino-1-(pyridylmethyl)piperidine and related compounds
US7368463B2 (en) 2003-07-11 2008-05-06 Theravance, Inc. Substituted 4-amino-1-benzylpiperidine compounds
US8673920B2 (en) 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8952166B2 (en) 2012-07-26 2015-02-10 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8999991B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8999990B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9056859B2 (en) 2010-10-29 2015-06-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9062070B2 (en) 2011-08-19 2015-06-23 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9073882B2 (en) 2010-10-27 2015-07-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9108947B2 (en) 2011-10-31 2015-08-18 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
US9139585B2 (en) 2011-10-31 2015-09-22 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
US9206199B2 (en) 2011-12-16 2015-12-08 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9493474B2 (en) 2011-10-31 2016-11-15 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9527830B2 (en) 2011-09-16 2016-12-27 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9573961B2 (en) 2012-12-19 2017-02-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9604998B2 (en) 2013-02-18 2017-03-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9751881B2 (en) 2013-07-31 2017-09-05 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9765074B2 (en) 2013-03-15 2017-09-19 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9777002B2 (en) 2012-11-29 2017-10-03 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US10160751B2 (en) 2015-02-12 2018-12-25 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3003843A1 (de) * 1980-02-02 1981-08-13 Chemische Werke Hüls AG, 4370 Marl Verfahren zur herstellung von 4-amino-2,2,6,6-tetramethylpiperidin
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
FR2534255B1 (fr) * 1982-10-11 1985-07-12 Delalande Sa Nouveaux derives de la 4-aroylamino piperidine, leur procede de preparation et leur application en therapeutique
FR2546169B1 (fr) * 1983-05-20 1986-03-21 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
US6517811B2 (en) 1993-05-06 2003-02-11 Research Corporation Technologies, Inc. Compounds for cancer imaging and therapy
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137896A (en) * 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5057525A (en) * 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
WO2001036385A1 (en) * 1999-11-17 2001-05-25 Kissei Pharmaceutical Co., Ltd. Hydroxyethoxybenzamide derivatives and drugs containing the same
US7285564B2 (en) 2002-10-30 2007-10-23 Theravance, Inc. Substituted 4-amino-1-(pyridylmethyl)piperidine and related compounds
WO2004046110A1 (ja) * 2002-11-15 2004-06-03 Yamanouchi Pharmaceutical Co., Ltd. メラニン凝集ホルモン受容体拮抗剤
US7368463B2 (en) 2003-07-11 2008-05-06 Theravance, Inc. Substituted 4-amino-1-benzylpiperidine compounds
US8080565B2 (en) 2003-07-11 2011-12-20 Theravance, Inc. Substituted 4-amino-benzylpiperidine compounds
US9018211B2 (en) 2009-05-06 2015-04-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8673920B2 (en) 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9073882B2 (en) 2010-10-27 2015-07-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9056859B2 (en) 2010-10-29 2015-06-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9062070B2 (en) 2011-08-19 2015-06-23 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9527830B2 (en) 2011-09-16 2016-12-27 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8999990B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8999991B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9493474B2 (en) 2011-10-31 2016-11-15 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9139585B2 (en) 2011-10-31 2015-09-22 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
US9108947B2 (en) 2011-10-31 2015-08-18 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
US9206199B2 (en) 2011-12-16 2015-12-08 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9206198B2 (en) 2012-07-26 2015-12-08 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US8952166B2 (en) 2012-07-26 2015-02-10 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9777002B2 (en) 2012-11-29 2017-10-03 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9573961B2 (en) 2012-12-19 2017-02-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9604998B2 (en) 2013-02-18 2017-03-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9765074B2 (en) 2013-03-15 2017-09-19 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9751881B2 (en) 2013-07-31 2017-09-05 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US10160751B2 (en) 2015-02-12 2018-12-25 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel

Also Published As

Publication number Publication date
FR2370731B1 (enExample) 1980-05-16
ES464149A1 (es) 1978-09-01
JPS5387364A (en) 1978-08-01
FR2370731A1 (fr) 1978-06-09
ES464148A1 (es) 1978-09-01
DE2751181A1 (de) 1978-05-24

Similar Documents

Publication Publication Date Title
GB1575310A (en) Piperidine derivatives
US4367232A (en) Piperidine derivatives
CA1095046A (en) N-piperid-4-yl-benzamide compounds
US4138492A (en) Aromatic amides of heterocyclic compounds and therapeutic compositions containing same
US3341538A (en) Certain 2, 6-methano-3-benzazocines
US3862143A (en) Substituted chromone-3-carbonitriles, carboxamides and carboxylic acids
US4929621A (en) 1-1[(2-pyrimidinyl)amino-alkyl]piperidines, their preparation and their application in therapy
US3666764A (en) Spiroindenylpiperidines
DE2311570A1 (de) 4-aminochinoline, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
EP0213775B1 (en) New benzamides
US4420485A (en) 1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]
FI60200B (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla n-arylalkylpiperidylsubstituerade bensamider
NO141160B (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3,4-dihydro-2(1h)-isokinolinkarboksamider
US4163789A (en) Anti-psychotic (cycloalkenylalkylpiperidino) benzamides
CA1094059A (en) Piperidine derivatives
GB1574419A (en) Piperidine compounds
DE3023717A1 (de) Neue schwefelhaltige isochinolinderivate, die diese verbindungen enthaltenden pharmazeutischen zubereitungen und verfahren zur herstellung der neuen verbindungen
US3970661A (en) 2-Amino, 5-carbamoyl pyridine compounds
CH628885A5 (en) Piperidine derivative
CZ285535B6 (cs) Deriváty 6-methoxy-1H-benzotriazol-5-karboxamidu, způsoby jejich výroby a farmaceutické preparáty na nich založené
CA1082710A (en) Preparation of aromatic amides
DE2513136A1 (de) Aromatische amide heterocyclischer verbindungen
US3631035A (en) 2-vinyl-1 4-dihydroquinazoline derivatives
US3859290A (en) 3-(1-(4-phenyl-4-oxobutyl)-4-hydroxy-4-piperidyl)dihydro-2(3h) furanones
GB2216516A (en) Piperidine derivatives

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee