GB153917A - Improvements in or relating to the preparation of tropinone mono-carboxylic acid esters - Google Patents

Improvements in or relating to the preparation of tropinone mono-carboxylic acid esters

Info

Publication number
GB153917A
GB153917A GB32349/20A GB3234920A GB153917A GB 153917 A GB153917 A GB 153917A GB 32349/20 A GB32349/20 A GB 32349/20A GB 3234920 A GB3234920 A GB 3234920A GB 153917 A GB153917 A GB 153917A
Authority
GB
United Kingdom
Prior art keywords
tropinone
mono
relating
preparation
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB32349/20A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck KGaA
Original Assignee
E Merck AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E Merck AG filed Critical E Merck AG
Publication of GB153917A publication Critical patent/GB153917A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Tropinone monocarboxylic esters are obtained by condensing acetoacetic esters with methylamine and succindialdehyde. In an example, the reaction using acetoacetic ethyl ester is effected in a well-cooled alcoholic solution. The product may be converted into ecgonine.
GB32349/20A 1919-08-23 1920-11-16 Improvements in or relating to the preparation of tropinone mono-carboxylic acid esters Expired GB153917A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE344031T 1919-08-23

Publications (1)

Publication Number Publication Date
GB153917A true GB153917A (en) 1922-03-16

Family

ID=6249491

Family Applications (3)

Application Number Title Priority Date Filing Date
GB32349/20A Expired GB153917A (en) 1919-08-23 1920-11-16 Improvements in or relating to the preparation of tropinone mono-carboxylic acid esters
GB32350/20A Expired GB153918A (en) 1919-08-23 1920-11-16 Improvements in or relating to the preparation of tropinone mono-carboxylic acid esters
GB32351/20A Expired GB153919A (en) 1919-08-23 1920-11-16 Improvements in or relating to the preparation of tropinone monocarboxylic acid esters

Family Applications After (2)

Application Number Title Priority Date Filing Date
GB32350/20A Expired GB153918A (en) 1919-08-23 1920-11-16 Improvements in or relating to the preparation of tropinone mono-carboxylic acid esters
GB32351/20A Expired GB153919A (en) 1919-08-23 1920-11-16 Improvements in or relating to the preparation of tropinone monocarboxylic acid esters

Country Status (4)

Country Link
CH (5) CH94604A (en)
DE (1) DE344031C (en)
FR (3) FR537760A (en)
GB (3) GB153917A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2932641A (en) * 1956-07-26 1960-04-12 Hoechst Ag Alpha, beta-butenolides of the pregnene, pregnane and allopregnane series and a process for preparing them

Also Published As

Publication number Publication date
FR537758A (en) 1922-05-30
GB153918A (en) 1922-02-13
FR537759A (en) 1922-05-30
CH94151A (en) 1922-04-01
DE344031C (en) 1921-11-12
CH93433A (en) 1922-03-01
CH94156A (en) 1922-04-17
GB153919A (en) 1922-02-16
CH94604A (en) 1922-06-01
FR537760A (en) 1922-05-30
CH93278A (en) 1922-03-01

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