GB1517971A - 8alpha-substituted ergoline i derivatives - Google Patents

8alpha-substituted ergoline i derivatives

Info

Publication number
GB1517971A
GB1517971A GB28238/75A GB2823875A GB1517971A GB 1517971 A GB1517971 A GB 1517971A GB 28238/75 A GB28238/75 A GB 28238/75A GB 2823875 A GB2823875 A GB 2823875A GB 1517971 A GB1517971 A GB 1517971A
Authority
GB
United Kingdom
Prior art keywords
8alpha
derivatives
substituted ergoline
ergoline
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28238/75A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH998374A external-priority patent/CH605936A5/de
Priority claimed from CH1103174A external-priority patent/CH605938A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1517971A publication Critical patent/GB1517971A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB28238/75A 1974-07-19 1975-07-04 8alpha-substituted ergoline i derivatives Expired GB1517971A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH998374A CH605936A5 (en) 1974-07-19 1974-07-19 8-Alpha-(Amino-or cyanomethyl)-ergoline derivs
CH1103174A CH605938A5 (en) 1974-08-13 1974-08-13 8-Alpha-(Amino-or cyanomethyl)-ergoline derivs

Publications (1)

Publication Number Publication Date
GB1517971A true GB1517971A (en) 1978-07-19

Family

ID=25705648

Family Applications (3)

Application Number Title Priority Date Filing Date
GB4649/78A Expired GB1517973A (en) 1974-07-19 1975-07-04 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
GB4648/78A Expired GB1517972A (en) 1974-07-19 1975-07-04 6-methyl-8alpha-cyanomethylergoline i
GB28238/75A Expired GB1517971A (en) 1974-07-19 1975-07-04 8alpha-substituted ergoline i derivatives

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB4649/78A Expired GB1517973A (en) 1974-07-19 1975-07-04 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
GB4648/78A Expired GB1517972A (en) 1974-07-19 1975-07-04 6-methyl-8alpha-cyanomethylergoline i

Country Status (17)

Country Link
JP (1) JPS5134199A (zh)
AU (1) AU505314B2 (zh)
CA (1) CA1073452A (zh)
DD (1) DD118635A5 (zh)
DE (1) DE2530577A1 (zh)
DK (2) DK143902C (zh)
ES (1) ES439548A1 (zh)
FI (1) FI61188C (zh)
FR (1) FR2282889A1 (zh)
GB (3) GB1517973A (zh)
HK (2) HK56980A (zh)
IE (1) IE41426B1 (zh)
IL (1) IL47735A (zh)
MY (2) MY8100217A (zh)
NL (1) NL7508416A (zh)
NO (1) NO752493L (zh)
PH (1) PH16594A (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2152507A (en) * 1984-01-12 1985-08-07 Sandoz Ltd 8a-acylaminoergolines
GB2185743A (en) * 1986-01-24 1987-07-29 Sandoz Ltd 8 alpha -Acylaminoergoline's
US4764517A (en) * 1980-07-25 1988-08-16 Sandoz Ltd. 8α-(N,N-diethylsulfamoylamino)-6-n-propyl ergoline useful as a prolactin secretion inhibitor, anti-parkinson, anti-depressant agent

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1573621A (en) * 1976-01-02 1980-08-28 Sandoz Ltd Acylated 6-methyl-8a-amino-ergoline i compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
IT1064473B (it) * 1976-11-24 1985-02-18 Simes Sulfamoil derivati dell'8-beta-amminometilergolina
BE889713A (fr) * 1980-07-25 1982-01-25 Sandoz Sa Nouveaux derives de l'ergoline, leur preparation et leur application comme medicaments
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
JPS58174081A (ja) * 1982-04-05 1983-10-13 Mitsubishi Heavy Ind Ltd 船内機関室通風装置
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.
AT392945B (de) * 1988-06-27 1991-07-10 Gerhard Mader Ges M B H Ing Lager- und transportbehaelter fuer schuettgueter und lose materialien
DE4033496A1 (de) * 1990-10-20 1992-04-23 Sandoz Ag Neue ergolinderivate, ihre herstellung und verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218323A (en) * 1965-11-16 Esters of i,g-dimethyl-b-ergolenyl carbamic acid
FR1360618A (fr) * 1963-06-17 1964-05-08 Sandoz Sa Nouveaux uréthanes de la série lysergique et leur préparation
CH507248A (de) * 1967-03-16 1971-05-15 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure
NL6818658A (zh) * 1968-01-18 1969-07-22
AR206772A1 (es) * 1972-07-21 1976-08-23 Lilly Co Eli Procedimiento para preparar una nueva d-2-halo-6-metil-8-ciano(carboxamido)metil ergolina

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4764517A (en) * 1980-07-25 1988-08-16 Sandoz Ltd. 8α-(N,N-diethylsulfamoylamino)-6-n-propyl ergoline useful as a prolactin secretion inhibitor, anti-parkinson, anti-depressant agent
GB2152507A (en) * 1984-01-12 1985-08-07 Sandoz Ltd 8a-acylaminoergolines
AU618290B2 (en) * 1984-01-12 1991-12-19 Novartis Ag A novel 8alpha-acylaminoergoline
GB2185743A (en) * 1986-01-24 1987-07-29 Sandoz Ltd 8 alpha -Acylaminoergoline's

Also Published As

Publication number Publication date
NL7508416A (nl) 1976-01-21
IL47735A (en) 1979-11-30
FI61188C (fi) 1982-06-10
DD118635A5 (zh) 1976-03-12
AU8316275A (en) 1977-01-20
NO752493L (zh) 1976-01-20
MY8100217A (en) 1981-12-31
DK143902B (da) 1981-10-26
DK298980A (da) 1980-07-10
IE41426B1 (en) 1980-01-02
DK145542C (da) 1983-05-02
IE41426L (en) 1976-01-19
HK56980A (en) 1980-10-16
PH16594A (en) 1983-11-22
FI752011A (zh) 1976-01-20
IL47735A0 (en) 1975-10-15
FR2282889B1 (zh) 1979-08-10
DK313175A (da) 1976-01-20
ES439548A1 (es) 1977-06-16
GB1517973A (en) 1978-07-19
DK143902C (da) 1982-04-13
JPS5134199A (zh) 1976-03-23
GB1517972A (en) 1978-07-19
DK145542B (da) 1982-12-06
DE2530577C2 (zh) 1990-11-08
DE2530577A1 (de) 1976-01-29
HK56880A (en) 1980-10-16
AU505314B2 (en) 1979-11-15
FI61188B (fi) 1982-02-26
FR2282889A1 (fr) 1976-03-26
CA1073452A (en) 1980-03-11
MY8100215A (en) 1981-12-31

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19930704