GB1511187A - Chromans - Google Patents
ChromansInfo
- Publication number
- GB1511187A GB1511187A GB13536/76A GB1353676A GB1511187A GB 1511187 A GB1511187 A GB 1511187A GB 13536/76 A GB13536/76 A GB 13536/76A GB 1353676 A GB1353676 A GB 1353676A GB 1511187 A GB1511187 A GB 1511187A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- optionally substituted
- group
- acyloxy
- precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052799 carbon Inorganic materials 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- AXWDPRJZZIUQPF-UHFFFAOYSA-N 2,2-dimethyl-1a,7b-dihydrooxireno[2,3-c]chromene Chemical compound CC1(C)OC2=CC=CC=C2C2C1O2 AXWDPRJZZIUQPF-UHFFFAOYSA-N 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- 101100203601 Caenorhabditis elegans sor-3 gene Proteins 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001843 chromanes Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 150000007857 hydrazones Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003333 secondary alcohols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (23)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB13536/76A GB1511187A (en) | 1976-04-02 | 1976-04-02 | Chromans |
NZ183551A NZ183551A (en) | 1976-04-02 | 1977-03-09 | Aminochromanols and pharmaceutical compositions containingthem |
IL51648A IL51648A (en) | 1976-04-02 | 1977-03-11 | 4-amino chromanol derivatives,their preparation and pharmaceutical compositions containing them |
ZA00771516A ZA771516B (en) | 1976-04-02 | 1977-03-14 | Anti-hypertensive acylated amino chromanolo |
FR7709151A FR2346346A1 (fr) | 1976-04-02 | 1977-03-28 | Nouveaux amino-chromanols |
DE19772713670 DE2713670A1 (de) | 1976-04-02 | 1977-03-28 | Aminochromanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate |
DE2760316A DE2760316C3 (de) | 1976-04-02 | 1977-03-28 | Derivate des 3,4-Epoxy-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyrans und ihre Verwendung zur Herstellung von 2H-Benzo[b]pyran-3-olen |
BE176178A BE852955A (fr) | 1976-04-02 | 1977-03-28 | Nouveaux amino-chromanols |
CH394477A CH632262A5 (de) | 1976-04-02 | 1977-03-29 | Verfahren zur herstellung von aminochromanol-derivaten. |
SE7703715A SE7703715L (sv) | 1976-04-02 | 1977-03-30 | Framstellning av nya aminokromanoler |
NL7703440A NL7703440A (nl) | 1976-04-02 | 1977-03-30 | Werkwijze voor het bereiden van nieuwe amino- chromanolderivaten, alsmede farmaceutische preparaten die deze verbindingen bevatten. |
JP3603477A JPS52122372A (en) | 1976-04-02 | 1977-03-30 | New aminochromanols and their preparation and medical composition containing same and having hypotensive effect |
ES457417A ES457417A1 (es) | 1976-04-02 | 1977-03-31 | Un procedimiento para la preparacion de nuevos aminocromano-les. |
IE694/77A IE44977B1 (en) | 1976-04-02 | 1977-04-01 | Chromans |
AU23875/77A AU503934B2 (en) | 1976-04-02 | 1977-04-01 | Amino chomanols |
DK147777A DK147777A (da) | 1976-04-02 | 1977-04-01 | Fremgangsmade til fremstilling af acylchromaner |
CA000275337A CA1119180A (en) | 1976-04-02 | 1977-04-01 | Derivatives of trans-3-hydroxy-4-amino-chromans |
US05/970,199 US4251537A (en) | 1976-04-02 | 1978-12-18 | Hypotensive 3,4-dihydro-2,2-dimethyl-4-amino-2H-benzo[b]pyran-3-ols |
US06/198,280 US4391815A (en) | 1976-04-02 | 1980-10-17 | Cyanobenzano[b]pyrans |
CA000376467A CA1139765A (en) | 1976-04-02 | 1981-04-28 | Amino chromanols |
US06/442,355 US4758677A (en) | 1976-04-02 | 1982-11-17 | Cyanobenzano [b] pyrans |
NL8402722A NL8402722A (nl) | 1976-04-02 | 1984-09-06 | Werkwijze voor het bereiden van nieuwe epoxy-benzopyranderivaten. |
JP60250599A JPS61129183A (ja) | 1976-04-02 | 1985-11-08 | 中間化合物及びその製法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB13536/76A GB1511187A (en) | 1976-04-02 | 1976-04-02 | Chromans |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1511187A true GB1511187A (en) | 1978-05-17 |
Family
ID=10024759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB13536/76A Expired GB1511187A (en) | 1976-04-02 | 1976-04-02 | Chromans |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPS61129183A (enrdf_load_stackoverflow) |
BE (1) | BE852955A (enrdf_load_stackoverflow) |
GB (1) | GB1511187A (enrdf_load_stackoverflow) |
ZA (1) | ZA771516B (enrdf_load_stackoverflow) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0046652A1 (en) * | 1980-08-21 | 1982-03-03 | Beecham Group Plc | Chromanol derivatives, their production and pharmaceutical compositions containing them |
US4327099A (en) | 1980-02-02 | 1982-04-27 | Beecham Group Limited | Pyrano derivatives, a process for their preparation and their use |
EP0076075A1 (en) * | 1981-09-25 | 1983-04-06 | Beecham Group Plc | Pharmaceutically active benzopyran compounds |
EP0091748A1 (en) * | 1982-04-08 | 1983-10-19 | Beecham Group Plc | Antihypertensive benzopyranols |
EP0107423A1 (en) * | 1982-10-19 | 1984-05-02 | Beecham Group Plc | Novel chromans and chromenes |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1495526A (en) * | 1974-05-31 | 1977-12-21 | Beecham Group Ltd | Chroman derivatives |
-
1976
- 1976-04-02 GB GB13536/76A patent/GB1511187A/en not_active Expired
-
1977
- 1977-03-14 ZA ZA00771516A patent/ZA771516B/xx unknown
- 1977-03-28 BE BE176178A patent/BE852955A/xx unknown
-
1985
- 1985-11-08 JP JP60250599A patent/JPS61129183A/ja active Granted
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4327099A (en) | 1980-02-02 | 1982-04-27 | Beecham Group Limited | Pyrano derivatives, a process for their preparation and their use |
EP0033612B1 (en) * | 1980-02-02 | 1984-04-11 | Beecham Group Plc | Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them |
EP0046652A1 (en) * | 1980-08-21 | 1982-03-03 | Beecham Group Plc | Chromanol derivatives, their production and pharmaceutical compositions containing them |
US4481213A (en) * | 1980-08-21 | 1984-11-06 | Beecham Group Limited | 4-Haloalkylamino substituted chromanol useful as antihypertensive agent |
EP0076075A1 (en) * | 1981-09-25 | 1983-04-06 | Beecham Group Plc | Pharmaceutically active benzopyran compounds |
EP0091748A1 (en) * | 1982-04-08 | 1983-10-19 | Beecham Group Plc | Antihypertensive benzopyranols |
EP0107423A1 (en) * | 1982-10-19 | 1984-05-02 | Beecham Group Plc | Novel chromans and chromenes |
Also Published As
Publication number | Publication date |
---|---|
JPS61129183A (ja) | 1986-06-17 |
ZA771516B (en) | 1978-02-22 |
JPH0353314B2 (enrdf_load_stackoverflow) | 1991-08-14 |
BE852955A (fr) | 1977-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |