GB1491509A - Metabolites s7481/f-1 and 1f-2 - Google Patents
Metabolites s7481/f-1 and 1f-2Info
- Publication number
- GB1491509A GB1491509A GB52013/74A GB5201374A GB1491509A GB 1491509 A GB1491509 A GB 1491509A GB 52013/74 A GB52013/74 A GB 52013/74A GB 5201374 A GB5201374 A GB 5201374A GB 1491509 A GB1491509 A GB 1491509A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- see
- decomp
- nrrl
- dec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002207 metabolite Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 241000875119 Cylindrocarpon lucidum Species 0.000 abstract 2
- 241000233866 Fungi Species 0.000 abstract 2
- 238000002844 melting Methods 0.000 abstract 2
- 230000008018 melting Effects 0.000 abstract 2
- 238000002211 ultraviolet spectrum Methods 0.000 abstract 2
- 241001149960 Tolypocladium inflatum Species 0.000 abstract 1
- 241001144069 Tolypocladium inflatum NRRL8044 Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
- C07K4/06—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof from fungi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/885—Trichoderma
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Botany (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Alternative & Traditional Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1711173A CH589716A5 (en) | 1973-12-06 | 1973-12-06 | Antibiotics S 7481-F-1 and 2 - prepd. from new strains of Cylindrocarbon or Trichoderma esp. useful as immunosuppressant |
CH1404374A CH603790A5 (en) | 1974-10-21 | 1974-10-21 | Antibiotics S 7481-F-1 and 2 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1491509A true GB1491509A (en) | 1977-11-09 |
Family
ID=25713544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB52013/74A Expired GB1491509A (en) | 1973-12-06 | 1974-12-02 | Metabolites s7481/f-1 and 1f-2 |
Country Status (19)
Country | Link |
---|---|
JP (1) | JPS5615235B2 (sv) |
AU (1) | AU500889B2 (sv) |
CA (1) | CA1030469A (sv) |
DD (1) | DD115695A5 (sv) |
DE (2) | DE2455859C2 (sv) |
DK (1) | DK136780B (sv) |
ES (1) | ES432559A1 (sv) |
FI (2) | FI52851C (sv) |
FR (1) | FR2253531B1 (sv) |
GB (1) | GB1491509A (sv) |
HK (1) | HK53880A (sv) |
IE (1) | IE40549B1 (sv) |
IL (1) | IL46180A (sv) |
MY (1) | MY8100203A (sv) |
NL (1) | NL179220C (sv) |
NO (1) | NO744292L (sv) |
NZ (1) | NZ176117A (sv) |
PH (1) | PH13773A (sv) |
SE (1) | SE423720B (sv) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4384996A (en) | 1981-01-09 | 1983-05-24 | Sandoz Ltd. | Novel cyclosporins |
US4396542A (en) | 1980-02-14 | 1983-08-02 | Sandoz Ltd. | Method for the total synthesis of cyclosporins, novel cyclosporins and novel intermediates and methods for their production |
US4554351A (en) * | 1980-02-14 | 1985-11-19 | Sandoz Ltd. | Method for the total synthesis of cyclosporins, novel cyclosporins and novel intermediates and methods for their production |
US5079341A (en) * | 1987-07-22 | 1992-01-07 | Galpin Ian J | Cyclosporins |
US5874572A (en) * | 1994-10-13 | 1999-02-23 | Chong Kun Dang Corp. | Process for preparing cyclosporin A |
US6255100B1 (en) | 1990-11-02 | 2001-07-03 | Novartis Ag | Cyclosporin fermentation process |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH614931A5 (sv) | 1975-11-04 | 1979-12-28 | Sandoz Ag | |
US4117118A (en) * | 1976-04-09 | 1978-09-26 | Sandoz Ltd. | Organic compounds |
SE445174B (sv) * | 1978-03-07 | 1986-06-09 | Sandoz Ag | Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans |
SE448386B (sv) * | 1978-10-18 | 1987-02-16 | Sandoz Ag | Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem |
JPS59129920U (ja) * | 1983-02-16 | 1984-08-31 | 日立造船株式会社 | ゲ−ト付バイパスバルブの開閉操作装置 |
WO1992013094A1 (fr) * | 1991-01-25 | 1992-08-06 | Fujisawa Pharmaceutical Co., Ltd. | Procede pour produire de la cyclosporine a et/ou c |
WO1996014079A1 (de) | 1994-11-03 | 1996-05-17 | Arzneimittelwerk Dresden Gmbh | Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung |
US6423233B1 (en) | 2000-08-15 | 2002-07-23 | Biogal Gyogyszergyar Rt. | Purification process |
JP2006524232A (ja) | 2003-03-17 | 2006-10-26 | アルバニー モレキュラー リサーチ インコーポレーティッド | 新規サイクロスポリン |
WO2006039163A2 (en) | 2004-09-29 | 2006-04-13 | Amr Technology, Inc. | Cyclosporin alkyne analogues and their pharmaceutical uses |
WO2006039164A2 (en) | 2004-09-29 | 2006-04-13 | Amr Technology, Inc. | Novel cyclosporin analogues and their pharmaceutical uses |
WO2006041631A2 (en) | 2004-10-06 | 2006-04-20 | Amr Technology, Inc. | Novel cyclosporin alkynes and their utility as pharmaceutical agents |
US7696166B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders |
US7696165B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders |
EP2151450A1 (de) * | 2008-07-29 | 2010-02-10 | Sandoz AG | Verfahren zur Aufarbeitung von mikrobiologisch hergestellten zyklischen Oligopeptiden |
-
1974
- 1974-11-26 DE DE2455859A patent/DE2455859C2/de not_active Expired
- 1974-11-26 DE DE2463138A patent/DE2463138C2/de not_active Expired
- 1974-11-27 FI FI743434A patent/FI52851C/sv active
- 1974-11-27 DK DK617074AA patent/DK136780B/da unknown
- 1974-11-28 NO NO744292A patent/NO744292L/no unknown
- 1974-11-29 SE SE7415027A patent/SE423720B/sv not_active IP Right Cessation
- 1974-12-02 NL NLAANVRAGE7415682,A patent/NL179220C/xx not_active IP Right Cessation
- 1974-12-02 GB GB52013/74A patent/GB1491509A/en not_active Expired
- 1974-12-04 ES ES432559A patent/ES432559A1/es not_active Expired
- 1974-12-04 DD DD182775A patent/DD115695A5/xx unknown
- 1974-12-04 AU AU76081/74A patent/AU500889B2/en not_active Expired
- 1974-12-04 IL IL46180A patent/IL46180A/xx unknown
- 1974-12-04 IE IE2502/74A patent/IE40549B1/xx not_active IP Right Cessation
- 1974-12-04 NZ NZ176117A patent/NZ176117A/xx unknown
- 1974-12-05 JP JP13893874A patent/JPS5615235B2/ja not_active Expired
- 1974-12-05 FR FR7439877A patent/FR2253531B1/fr not_active Expired
- 1974-12-05 CA CA215,287A patent/CA1030469A/en not_active Expired
-
1977
- 1977-04-15 FI FI771201A patent/FI54606C/fi not_active IP Right Cessation
- 1977-04-22 PH PH19702A patent/PH13773A/en unknown
-
1980
- 1980-09-25 HK HK538/80A patent/HK53880A/xx unknown
-
1981
- 1981-12-30 MY MY203/81A patent/MY8100203A/xx unknown
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4396542A (en) | 1980-02-14 | 1983-08-02 | Sandoz Ltd. | Method for the total synthesis of cyclosporins, novel cyclosporins and novel intermediates and methods for their production |
US4554351A (en) * | 1980-02-14 | 1985-11-19 | Sandoz Ltd. | Method for the total synthesis of cyclosporins, novel cyclosporins and novel intermediates and methods for their production |
US4384996A (en) | 1981-01-09 | 1983-05-24 | Sandoz Ltd. | Novel cyclosporins |
US5079341A (en) * | 1987-07-22 | 1992-01-07 | Galpin Ian J | Cyclosporins |
US6255100B1 (en) | 1990-11-02 | 2001-07-03 | Novartis Ag | Cyclosporin fermentation process |
US5874572A (en) * | 1994-10-13 | 1999-02-23 | Chong Kun Dang Corp. | Process for preparing cyclosporin A |
Also Published As
Publication number | Publication date |
---|---|
MY8100203A (en) | 1981-12-31 |
AU7608174A (en) | 1976-06-10 |
IL46180A (en) | 1978-07-31 |
DE2463138C2 (de) | 1984-07-05 |
HK53880A (en) | 1980-10-03 |
JPS5615235B2 (sv) | 1981-04-09 |
NL179220B (nl) | 1986-03-03 |
FI52851B (sv) | 1977-08-31 |
DK617074A (sv) | 1975-07-28 |
FI771201A (sv) | 1977-04-15 |
IE40549L (en) | 1975-06-06 |
FI54606B (fi) | 1978-09-29 |
DK136780B (da) | 1977-11-21 |
JPS5089598A (sv) | 1975-07-18 |
SE423720B (sv) | 1982-05-24 |
IL46180A0 (en) | 1975-03-13 |
DD115695A5 (sv) | 1975-10-12 |
NO744292L (sv) | 1975-06-30 |
SE7415027L (sv) | 1975-06-09 |
FR2253531B1 (sv) | 1978-07-21 |
PH13773A (en) | 1980-09-23 |
FI54606C (fi) | 1979-01-10 |
FI343474A (sv) | 1975-06-07 |
NL7415682A (nl) | 1975-06-10 |
FI52851C (sv) | 1977-12-12 |
DE2455859A1 (de) | 1975-06-12 |
AU500889B2 (en) | 1979-06-07 |
CA1030469A (en) | 1978-05-02 |
DE2455859C2 (de) | 1983-12-15 |
NL179220C (nl) | 1986-08-01 |
DK136780C (sv) | 1978-05-01 |
ES432559A1 (es) | 1977-03-01 |
NZ176117A (en) | 1981-05-01 |
FR2253531A1 (sv) | 1975-07-04 |
IE40549B1 (en) | 1979-06-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
PE20 | Patent expired after termination of 20 years |
Effective date: 19941201 |