ES475178A1 - Un metodo mejorado para producir antibiotico c-15003 p-3. - Google Patents
Un metodo mejorado para producir antibiotico c-15003 p-3.Info
- Publication number
- ES475178A1 ES475178A1 ES78475178A ES475178A ES475178A1 ES 475178 A1 ES475178 A1 ES 475178A1 ES 78475178 A ES78475178 A ES 78475178A ES 475178 A ES475178 A ES 475178A ES 475178 A1 ES475178 A1 ES 475178A1
- Authority
- ES
- Spain
- Prior art keywords
- antibiotic
- producing antibiotic
- antiprotozoan
- antifungal
- cultivating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/365—Nocardia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/872—Nocardia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Un método mejorado para producir antibiótico C-15003 p-3 cultivando un microorganismo que pertenece al genero Nocardia y que es capaz de producir el antibiótico C-15003 p-3 en un medio de cultivo que contiene fuentes de carbono asimilable y fuentes de nitrógeno digestible, que comprende incorporar valina, ácido isobutirico y/o sus derivados, como substancias aditivas, al medio de cultivo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52139385A JPS6016236B2 (ja) | 1977-11-18 | 1977-11-18 | 抗生物質c―15003 p―3の製造法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES475178A1 true ES475178A1 (es) | 1979-05-16 |
Family
ID=15244070
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES78475178A Expired ES475178A1 (es) | 1977-11-18 | 1978-11-17 | Un metodo mejorado para producir antibiotico c-15003 p-3. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4228239A (es) |
JP (1) | JPS6016236B2 (es) |
CH (1) | CH640270A5 (es) |
DE (1) | DE2849696A1 (es) |
DK (1) | DK144657C (es) |
ES (1) | ES475178A1 (es) |
FR (1) | FR2409307A1 (es) |
GB (1) | GB2011385B (es) |
HU (1) | HU179600B (es) |
IT (1) | IT1206651B (es) |
NL (1) | NL7811325A (es) |
PL (1) | PL122463B1 (es) |
SU (1) | SU1036251A3 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4162940A (en) * | 1977-03-31 | 1979-07-31 | Takeda Chemical Industries, Ltd. | Method for producing Antibiotic C-15003 by culturing nocardia |
JPS55162791A (en) * | 1979-06-05 | 1980-12-18 | Takeda Chem Ind Ltd | Antibiotic c-15003pnd and its preparation |
JPS5645483A (en) * | 1979-09-19 | 1981-04-25 | Takeda Chem Ind Ltd | C-15003phm and its preparation |
JPS56102793A (en) * | 1979-12-28 | 1981-08-17 | Takeda Chem Ind Ltd | Preparation of antibiotic c-15003 p-3 |
US6573074B2 (en) | 2000-04-12 | 2003-06-03 | Smithkline Beecham Plc | Methods for ansamitocin production |
US20110313230A1 (en) | 2001-05-11 | 2011-12-22 | Terrance Grant Johns | Specific binding proteins and uses thereof |
US6790954B2 (en) * | 2002-01-29 | 2004-09-14 | Immunogen, Inc. | Mutant Actinosynnema pretiosum strain with increased maytansinoid production |
JP2006510349A (ja) * | 2002-08-08 | 2006-03-30 | スミスクライン・ビーチャム・コーポレイション | アンサミトシンの単離および精製方法 |
US7432088B2 (en) | 2003-05-08 | 2008-10-07 | Immunogen Inc. | Methods for the production of ansamitocins |
US20070135629A1 (en) * | 2005-12-08 | 2007-06-14 | Millennium Pharmaceuticals, Inc. | Isolation of ansamitocins |
US20110076232A1 (en) | 2009-09-29 | 2011-03-31 | Ludwig Institute For Cancer Research | Specific binding proteins and uses thereof |
CN101921817A (zh) * | 2010-09-07 | 2010-12-22 | 上海交通大学 | 安莎霉素发酵产量提高方法 |
AU2013234499B2 (en) * | 2012-03-17 | 2017-07-27 | Polyphor Ag | Conformationally constrained, fully synthetic macrocyclic compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3902968A (en) * | 1974-04-25 | 1975-09-02 | Merck & Co Inc | Fermentation process |
JPS58876B2 (ja) * | 1975-11-19 | 1983-01-08 | 藤沢薬品工業株式会社 | Fr −1923 ブツシツノ セイゾウホウホウ |
US4162940A (en) * | 1977-03-31 | 1979-07-31 | Takeda Chemical Industries, Ltd. | Method for producing Antibiotic C-15003 by culturing nocardia |
JPS6010718B2 (ja) * | 1977-03-31 | 1985-03-19 | 武田薬品工業株式会社 | メイタンシノ−ル,メイタナシンおよびメイタンシノ−ル・プロピオネ−トの製造法 |
US4151042A (en) * | 1977-03-31 | 1979-04-24 | Takeda Chemical Industries, Ltd. | Method for producing maytansinol and its derivatives |
FR2385714A1 (fr) * | 1977-03-31 | 1978-10-27 | Takeda Chemical Industries Ltd | Nouvel antibiotique denomme c-15003, son procede de preparation et son application comme medicament |
-
1977
- 1977-11-18 JP JP52139385A patent/JPS6016236B2/ja not_active Expired
-
1978
- 1978-11-13 US US05/959,602 patent/US4228239A/en not_active Expired - Lifetime
- 1978-11-16 CH CH1180078A patent/CH640270A5/de not_active IP Right Cessation
- 1978-11-16 NL NL7811325A patent/NL7811325A/xx not_active Application Discontinuation
- 1978-11-16 DE DE19782849696 patent/DE2849696A1/de not_active Withdrawn
- 1978-11-17 PL PL1978211028A patent/PL122463B1/pl unknown
- 1978-11-17 HU HU78TA1500A patent/HU179600B/hu unknown
- 1978-11-17 SU SU782688152A patent/SU1036251A3/ru active
- 1978-11-17 FR FR7832577A patent/FR2409307A1/fr active Granted
- 1978-11-17 IT IT7829922A patent/IT1206651B/it active
- 1978-11-17 ES ES78475178A patent/ES475178A1/es not_active Expired
- 1978-11-17 DK DK514378A patent/DK144657C/da not_active IP Right Cessation
- 1978-11-20 GB GB7845285A patent/GB2011385B/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IT1206651B (it) | 1989-04-27 |
PL211028A1 (pl) | 1979-07-16 |
DK514378A (da) | 1979-05-19 |
JPS6016236B2 (ja) | 1985-04-24 |
FR2409307B1 (es) | 1981-03-06 |
DK144657B (da) | 1982-05-03 |
DE2849696A1 (de) | 1979-05-23 |
NL7811325A (nl) | 1979-05-22 |
CH640270A5 (de) | 1983-12-30 |
SU1036251A3 (ru) | 1983-08-15 |
PL122463B1 (en) | 1982-07-31 |
GB2011385B (en) | 1982-05-26 |
JPS5473194A (en) | 1979-06-12 |
GB2011385A (en) | 1979-07-11 |
HU179600B (en) | 1982-11-29 |
IT7829922A0 (it) | 1978-11-17 |
US4228239A (en) | 1980-10-14 |
DK144657C (da) | 1982-11-22 |
FR2409307A1 (fr) | 1979-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19971201 |