GB1481251A - Preparation of 2-aminomethyl-pyrrolidine - Google Patents
Preparation of 2-aminomethyl-pyrrolidineInfo
- Publication number
- GB1481251A GB1481251A GB7645/75A GB764575A GB1481251A GB 1481251 A GB1481251 A GB 1481251A GB 7645/75 A GB7645/75 A GB 7645/75A GB 764575 A GB764575 A GB 764575A GB 1481251 A GB1481251 A GB 1481251A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrrolidine
- aminomethyl
- benzyl
- acid
- aminomethylpyrrolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AUKXFNABVHIUAC-UHFFFAOYSA-N pyrrolidin-2-ylmethylamine Chemical compound NCC1CCCN1 AUKXFNABVHIUAC-UHFFFAOYSA-N 0.000 title abstract 6
- 239000002253 acid Substances 0.000 abstract 3
- OEYAFMGVIFWPQI-UHFFFAOYSA-N (1-benzylpyrrolidin-2-yl)methanamine Chemical compound NCC1CCCN1CC1=CC=CC=C1 OEYAFMGVIFWPQI-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- QGRRJDFZPVWRGG-UHFFFAOYSA-N 1-benzyl-2-(nitromethylidene)pyrrolidine Chemical compound [O-][N+](=O)C=C1CCCN1CC1=CC=CC=C1 QGRRJDFZPVWRGG-UHFFFAOYSA-N 0.000 abstract 1
- LVUQCTGSDJLWCE-UHFFFAOYSA-N 1-benzylpyrrolidin-2-one Chemical compound O=C1CCCN1CC1=CC=CC=C1 LVUQCTGSDJLWCE-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- -1 benzyl compound Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- LYGJENNIWJXYER-UHFFFAOYSA-N nitromethane Chemical compound C[N+]([O-])=O LYGJENNIWJXYER-UHFFFAOYSA-N 0.000 abstract 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7407342A FR2263239B1 (en, 2012) | 1974-03-04 | 1974-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1481251A true GB1481251A (en) | 1977-07-27 |
Family
ID=9135811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7645/75A Expired GB1481251A (en) | 1974-03-04 | 1975-02-24 | Preparation of 2-aminomethyl-pyrrolidine |
Country Status (33)
| Country | Link |
|---|---|
| JP (1) | JPS5948825B2 (en, 2012) |
| AR (1) | AR207350A1 (en, 2012) |
| AT (1) | AT358569B (en, 2012) |
| BE (1) | BE825728A (en, 2012) |
| BG (1) | BG25077A3 (en, 2012) |
| CA (1) | CA1047041A (en, 2012) |
| CH (1) | CH602636A5 (en, 2012) |
| CS (1) | CS179935B2 (en, 2012) |
| DD (1) | DD117450A5 (en, 2012) |
| DE (1) | DE2506515A1 (en, 2012) |
| DK (1) | DK83875A (en, 2012) |
| EG (1) | EG11753A (en, 2012) |
| ES (1) | ES435139A1 (en, 2012) |
| FI (1) | FI750558A7 (en, 2012) |
| FR (1) | FR2263239B1 (en, 2012) |
| GB (1) | GB1481251A (en, 2012) |
| HK (1) | HK27878A (en, 2012) |
| HU (1) | HU169274B (en, 2012) |
| IE (1) | IE40685B1 (en, 2012) |
| IL (1) | IL46657A (en, 2012) |
| LU (1) | LU71947A1 (en, 2012) |
| MW (1) | MW875A1 (en, 2012) |
| NL (1) | NL7502425A (en, 2012) |
| NO (1) | NO145439C (en, 2012) |
| OA (1) | OA04856A (en, 2012) |
| PH (1) | PH11269A (en, 2012) |
| PL (1) | PL94801B1 (en, 2012) |
| RO (1) | RO64007A (en, 2012) |
| SE (1) | SE401367B (en, 2012) |
| SU (1) | SU591139A3 (en, 2012) |
| YU (1) | YU36500B (en, 2012) |
| ZA (1) | ZA751072B (en, 2012) |
| ZM (1) | ZM2775A1 (en, 2012) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988001866A1 (en) * | 1986-09-09 | 1988-03-24 | Adria Laboratories, Inc. | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1785124A1 (de) * | 1968-08-13 | 1971-11-11 | Prym Werke William | Reissverschluss |
| JPS5146901B2 (en, 2012) * | 1971-08-24 | 1976-12-11 | ||
| CH556836A (de) * | 1971-09-30 | 1974-12-13 | Fratmann Ag | Verfahren zur herstellung von 1-alkenyl-2-aminomethylpyrrolidinen. |
| NL7304089A (en, 2012) * | 1972-03-30 | 1973-10-02 | ||
| CH573404A5 (en, 2012) * | 1972-07-28 | 1976-03-15 | Inventa Ag |
-
1974
- 1974-03-04 CH CH272675A patent/CH602636A5/xx not_active IP Right Cessation
- 1974-03-04 FR FR7407342A patent/FR2263239B1/fr not_active Expired
- 1974-03-04 RO RO7400081539A patent/RO64007A/ro unknown
-
1975
- 1975-01-01 AR AR257827A patent/AR207350A1/es active
- 1975-02-15 DE DE19752506515 patent/DE2506515A1/de active Pending
- 1975-02-18 IL IL46657A patent/IL46657A/en unknown
- 1975-02-20 ZA ZA00751072A patent/ZA751072B/xx unknown
- 1975-02-20 BE BE1006472A patent/BE825728A/xx not_active IP Right Cessation
- 1975-02-24 IE IE377/75A patent/IE40685B1/xx unknown
- 1975-02-24 GB GB7645/75A patent/GB1481251A/en not_active Expired
- 1975-02-25 EG EG93/75A patent/EG11753A/xx active
- 1975-02-26 FI FI750558A patent/FI750558A7/fi not_active Application Discontinuation
- 1975-02-26 CA CA220,855A patent/CA1047041A/en not_active Expired
- 1975-02-27 ES ES435139A patent/ES435139A1/es not_active Expired
- 1975-02-28 NL NL7502425A patent/NL7502425A/xx not_active Application Discontinuation
- 1975-02-28 MW MW8/75A patent/MW875A1/xx unknown
- 1975-03-03 BG BG029132A patent/BG25077A3/xx unknown
- 1975-03-03 DK DK83875*#A patent/DK83875A/da not_active Application Discontinuation
- 1975-03-03 LU LU71947A patent/LU71947A1/xx unknown
- 1975-03-03 AT AT160575A patent/AT358569B/de not_active IP Right Cessation
- 1975-03-03 SE SE7502340A patent/SE401367B/xx not_active IP Right Cessation
- 1975-03-03 DD DD184512A patent/DD117450A5/xx unknown
- 1975-03-03 HU HUSO1136A patent/HU169274B/hu not_active IP Right Cessation
- 1975-03-03 PH PH16855A patent/PH11269A/en unknown
- 1975-03-03 NO NO750699A patent/NO145439C/no unknown
- 1975-03-03 PL PL1975178472A patent/PL94801B1/pl unknown
- 1975-03-03 SU SU752111076A patent/SU591139A3/ru active
- 1975-03-04 JP JP50026947A patent/JPS5948825B2/ja not_active Expired
- 1975-03-04 ZM ZM27/75A patent/ZM2775A1/xx unknown
- 1975-03-04 CS CS7500001451A patent/CS179935B2/cs unknown
- 1975-03-04 OA OA55432A patent/OA04856A/xx unknown
- 1975-03-19 YU YU00676/75A patent/YU36500B/xx unknown
-
1978
- 1978-06-01 HK HK278/78A patent/HK27878A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988001866A1 (en) * | 1986-09-09 | 1988-03-24 | Adria Laboratories, Inc. | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein |
| US4772459A (en) * | 1986-09-09 | 1988-09-20 | Erbamont, Inc. | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19930224 |