GB936417A - Benzene-sulphonamides and process of preparing them - Google Patents
Benzene-sulphonamides and process of preparing themInfo
- Publication number
- GB936417A GB936417A GB44528/60A GB4452860A GB936417A GB 936417 A GB936417 A GB 936417A GB 44528/60 A GB44528/60 A GB 44528/60A GB 4452860 A GB4452860 A GB 4452860A GB 936417 A GB936417 A GB 936417A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- dihalo
- salts
- sulphonamides
- benzoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises benzene-sulphonamides of the formula <FORM:0936417/IV(a)/1> wherein X is chlorine or bromine, R is a benzylamino, dibenzylamino, furfurylamino or thenylamino group and salts of these compounds, such as the triethylamine, triethanolamine, dimethylaniline, dicyclohexylamine, ammonium, alkali-metal and alkaline-earth metal (including magnesium) salts. The compounds are prepared by treating a 2 : 4-dihalo-5-sulphamoyl-benzoic acid (obtainable by chlorosulphonating a 2 : 4-dihalo-benzoic acid and reacting the resulting sulphonyl chloride with ammonia) with an amine RH. Pharmaceutical preparations having diuretic and saliuretic activity comprise the above compounds of the invention in admixture or conjunction with a carrier suitable for oral or parenteral administration. The preparations suitably take the form of tablets, dragees, capsules, solutions, suspensions or emulsions.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEF30189A DE1122541B (en) | 1959-12-28 | 1959-12-28 | Process for the production of sulfamyl-anthranilic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
GB936417A true GB936417A (en) | 1963-09-11 |
Family
ID=7093652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB44528/60A Expired GB936417A (en) | 1959-12-28 | 1960-12-28 | Benzene-sulphonamides and process of preparing them |
Country Status (6)
Country | Link |
---|---|
BE (1) | BE598606A (en) |
CH (1) | CH390936A (en) |
CY (1) | CY285A (en) |
GB (1) | GB936417A (en) |
MY (1) | MY6400078A (en) |
OA (1) | OA01639A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3493584A (en) * | 1966-02-21 | 1970-02-03 | Smithkline Corp | 4-substituted amino-5-sulfamoylbenzoic acid derivatives and preparation |
FR2302101A1 (en) * | 1975-02-27 | 1976-09-24 | Joullie International Sa | New 4-chloro 5-substd. sulphamoyl anthranilic acid - useful as diuretic and prepd. from new 2,4-dichloro benzoic acid |
-
1960
- 1960-12-20 CH CH1419860A patent/CH390936A/en unknown
- 1960-12-28 GB GB44528/60A patent/GB936417A/en not_active Expired
- 1960-12-28 BE BE598606A patent/BE598606A/en unknown
-
1964
- 1964-04-14 CY CY28564A patent/CY285A/en unknown
- 1964-12-31 OA OA51818A patent/OA01639A/en unknown
- 1964-12-31 MY MY196478A patent/MY6400078A/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3493584A (en) * | 1966-02-21 | 1970-02-03 | Smithkline Corp | 4-substituted amino-5-sulfamoylbenzoic acid derivatives and preparation |
FR2302101A1 (en) * | 1975-02-27 | 1976-09-24 | Joullie International Sa | New 4-chloro 5-substd. sulphamoyl anthranilic acid - useful as diuretic and prepd. from new 2,4-dichloro benzoic acid |
Also Published As
Publication number | Publication date |
---|---|
CY285A (en) | 1964-04-14 |
OA01639A (en) | 1969-09-20 |
BE598606A (en) | 1961-06-28 |
CH390936A (en) | 1965-04-30 |
MY6400078A (en) | 1964-12-31 |
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