GB1480637A - 2-hydroxynicotinic acid derivative and methods of preparing same - Google Patents
2-hydroxynicotinic acid derivative and methods of preparing sameInfo
- Publication number
- GB1480637A GB1480637A GB41018/74A GB4101874A GB1480637A GB 1480637 A GB1480637 A GB 1480637A GB 41018/74 A GB41018/74 A GB 41018/74A GB 4101874 A GB4101874 A GB 4101874A GB 1480637 A GB1480637 A GB 1480637A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- dimethylaniline
- methods
- hydroxynicotinic acid
- acid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UEYQJQVBUVAELZ-UHFFFAOYSA-N 2-Hydroxynicotinic acid Chemical class OC(=O)C1=CC=CN=C1O UEYQJQVBUVAELZ-UHFFFAOYSA-N 0.000 title abstract 2
- UFFBMTHBGFGIHF-UHFFFAOYSA-N 2,6-dimethylaniline Chemical compound CC1=CC=CC(C)=C1N UFFBMTHBGFGIHF-UHFFFAOYSA-N 0.000 abstract 6
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 241000405147 Hermes Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910000272 alkali metal oxide Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910001860 alkaline earth metal hydroxide Inorganic materials 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES428449A ES428449A1 (es) | 1974-07-20 | 1974-07-20 | Procedimiento para la obtencion de un nuevo derivado de la 2-piridona. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1480637A true GB1480637A (en) | 1977-07-20 |
Family
ID=8467178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB41018/74A Expired GB1480637A (en) | 1974-07-20 | 1974-09-20 | 2-hydroxynicotinic acid derivative and methods of preparing same |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5176279A (enrdf_load_stackoverflow) |
| BE (1) | BE820578A (enrdf_load_stackoverflow) |
| DE (1) | DE2461653B2 (enrdf_load_stackoverflow) |
| ES (1) | ES428449A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2278685A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1480637A (enrdf_load_stackoverflow) |
| IT (1) | IT1049428B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4973597A (en) * | 1989-06-30 | 1990-11-27 | Eli Lilly And Company | Anticonvulsant agents |
-
1974
- 1974-07-20 ES ES428449A patent/ES428449A1/es not_active Expired
- 1974-09-20 GB GB41018/74A patent/GB1480637A/en not_active Expired
- 1974-09-24 FR FR7432079A patent/FR2278685A1/fr active Granted
- 1974-09-26 JP JP49110935A patent/JPS5176279A/ja active Granted
- 1974-09-30 BE BE6044763A patent/BE820578A/xx not_active IP Right Cessation
- 1974-12-27 DE DE2461653A patent/DE2461653B2/de active Granted
-
1975
- 1975-05-22 IT IT23632/75A patent/IT1049428B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| DE2461653C3 (enrdf_load_stackoverflow) | 1979-04-26 |
| FR2278685B1 (enrdf_load_stackoverflow) | 1979-02-16 |
| BE820578A (fr) | 1975-01-16 |
| DE2461653A1 (de) | 1976-01-29 |
| DE2461653B2 (de) | 1978-08-31 |
| ES428449A1 (es) | 1976-08-16 |
| JPS5521747B2 (enrdf_load_stackoverflow) | 1980-06-12 |
| FR2278685A1 (fr) | 1976-02-13 |
| IT1049428B (it) | 1981-01-20 |
| JPS5176279A (en) | 1976-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee | ||
| 728C | Application made for restoration (sect. 28/1977) | ||
| 728P | Application not proceeded with (sect. 28/1977) |