GB1475513A - Benzylamine derivatives process for science union et cie benzylamine derivatives process for their production and pharmaceutical compositions containing them - Google Patents
Benzylamine derivatives process for science union et cie benzylamine derivatives process for their production and pharmaceutical compositions containing themInfo
- Publication number
- GB1475513A GB1475513A GB2739274A GB2739274A GB1475513A GB 1475513 A GB1475513 A GB 1475513A GB 2739274 A GB2739274 A GB 2739274A GB 2739274 A GB2739274 A GB 2739274A GB 1475513 A GB1475513 A GB 1475513A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- benzylamine derivatives
- lower alkyl
- derivatives process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003939 benzylamines Chemical class 0.000 title 2
- -1 alkyl radical Chemical class 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical group F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 1
- MUCRYNWJQNHDJH-OADIDDRXSA-N Ursonic acid Chemical compound C1CC(=O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C MUCRYNWJQNHDJH-OADIDDRXSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- ATDGTVJJHBUTRL-UHFFFAOYSA-N cyanogen bromide Chemical compound BrC#N ATDGTVJJHBUTRL-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 150000002918 oxazolines Chemical class 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2739274A GB1475513A (en) | 1974-06-20 | 1974-06-20 | Benzylamine derivatives process for science union et cie benzylamine derivatives process for their production and pharmaceutical compositions containing them |
| CA229,350A CA1062265A (fr) | 1974-06-20 | 1975-06-13 | Procede de preparation de nouvelles benzylamines |
| DE19752526965 DE2526965A1 (de) | 1974-06-20 | 1975-06-16 | Benzylamine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel |
| IE1361/75A IE41382B1 (en) | 1974-06-20 | 1975-06-17 | Benzylamine derivatives process for their production and pharmaceutical compositions containing them |
| SE7507018A SE7507018L (sv) | 1974-06-20 | 1975-06-18 | Sett att framstella nya bensylaminer. |
| FI751825A FI751825A7 (enrdf_load_stackoverflow) | 1974-06-20 | 1975-06-18 | |
| DK274375AA DK136313B (da) | 1974-06-20 | 1975-06-18 | Analogifremgangsmåde til fremstilling af N-substituerede m-trifluormethylbenzylaminer. |
| AT471675A AT342046B (de) | 1974-06-20 | 1975-06-19 | Verfahren zur herstellung von neuen n-benzylaminooxazolinen |
| JP50074996A JPS5231341B2 (enrdf_load_stackoverflow) | 1974-06-20 | 1975-06-19 | |
| AU82246/75A AU497501B2 (en) | 1974-06-20 | 1975-06-19 | Benzylamines |
| BE157510A BE830442A (fr) | 1974-06-20 | 1975-06-19 | Nouvelles benzylamines leur preparation et les compositions pharmaceutiques en contenant |
| HU75SI1474A HU173390B (hu) | 1974-06-20 | 1975-06-19 | Sposob poluchenija novykh proizvodnykh benzilamina |
| ZA00753943A ZA753943B (en) | 1974-06-20 | 1975-06-19 | Novel benzylamines, a process for making them and pharmaceutical compositions |
| CH801275A CH597206A5 (enrdf_load_stackoverflow) | 1974-06-20 | 1975-06-19 | |
| SU7502145925A SU578880A3 (ru) | 1974-06-20 | 1975-06-19 | Способ получени бензиламинооксазолинов или их солей или их оптических изомеров |
| FR7519164A FR2275207A1 (fr) | 1974-06-20 | 1975-06-19 | Nouvelles benzylamines leur preparation et les compositions pharmaceutiques en contenant |
| NL7507422A NL7507422A (nl) | 1974-06-20 | 1975-06-20 | Werkwijze voor de bereiding van een geneesmiddel met bloeddrukverlagende werking, een dergelijk ge- neesmiddel en een werkwijze voor de bereiding van de actieve verbindingen. |
| ES438757A ES438757A1 (es) | 1974-06-20 | 1975-06-20 | Un procedimiento de obtencion de las meta-trifluormetilben- cilaminas sustituidas al nitrogeno. |
| DK141477A DK141477A (da) | 1974-06-20 | 1977-03-31 | M-trifluormethylbenzylaminforbindelser til anvendelse som melllenprodukter ved fremstilling af n-substituerede m-trifluormethylbenzylaminer |
| DK141377A DK138742B (da) | 1974-06-20 | 1977-03-31 | Fremgangsmåde til fremstilling af 2-aminooxazolinderivater. |
| AT402777A AT349464B (de) | 1974-06-20 | 1977-06-07 | Verfahren zur herstellung von neuen n- benzylamino-oxazolinen |
| SE7900681A SE7900681L (sv) | 1974-06-20 | 1979-01-25 | Substituerade trifluormetylbensylkarbamider till anvendning som mellanprodukter for framstellning av kveve-substituerade trifluormetylbensylaminer och sett att framstella karbamiderna |
| CA332,309A CA1078869A (fr) | 1974-06-20 | 1979-07-20 | Procede de preparation de nouvelles benzylamines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2739274A GB1475513A (en) | 1974-06-20 | 1974-06-20 | Benzylamine derivatives process for science union et cie benzylamine derivatives process for their production and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1475513A true GB1475513A (en) | 1977-06-01 |
Family
ID=10258850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2739274A Expired GB1475513A (en) | 1974-06-20 | 1974-06-20 | Benzylamine derivatives process for science union et cie benzylamine derivatives process for their production and pharmaceutical compositions containing them |
Country Status (18)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2951247A1 (de) * | 1978-12-20 | 1980-07-03 | Science Union & Cie | N-substituierte trifluoraethylamine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2358890A1 (fr) * | 1976-05-24 | 1978-02-17 | Science Union & Cie | Nouvelles aryl trifluoroethylamines, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant |
| JPS53105752U (enrdf_load_stackoverflow) * | 1977-01-31 | 1978-08-25 | ||
| JPS5495252A (en) * | 1978-01-11 | 1979-07-27 | Oki Electric Ind Co Ltd | Thermal printer |
| JPS57136755U (enrdf_load_stackoverflow) * | 1981-02-20 | 1982-08-26 | ||
| AUPP020297A0 (en) * | 1997-11-05 | 1997-11-27 | University Of Melbourne, The | A novel receptor, and compounds which bind thereto |
-
1974
- 1974-06-20 GB GB2739274A patent/GB1475513A/en not_active Expired
-
1975
- 1975-06-13 CA CA229,350A patent/CA1062265A/fr not_active Expired
- 1975-06-16 DE DE19752526965 patent/DE2526965A1/de active Pending
- 1975-06-17 IE IE1361/75A patent/IE41382B1/xx unknown
- 1975-06-18 DK DK274375AA patent/DK136313B/da unknown
- 1975-06-18 SE SE7507018A patent/SE7507018L/xx unknown
- 1975-06-18 FI FI751825A patent/FI751825A7/fi not_active Application Discontinuation
- 1975-06-19 AT AT471675A patent/AT342046B/de not_active IP Right Cessation
- 1975-06-19 FR FR7519164A patent/FR2275207A1/fr active Granted
- 1975-06-19 ZA ZA00753943A patent/ZA753943B/xx unknown
- 1975-06-19 JP JP50074996A patent/JPS5231341B2/ja not_active Expired
- 1975-06-19 BE BE157510A patent/BE830442A/xx unknown
- 1975-06-19 AU AU82246/75A patent/AU497501B2/en not_active Expired
- 1975-06-19 CH CH801275A patent/CH597206A5/xx not_active IP Right Cessation
- 1975-06-19 HU HU75SI1474A patent/HU173390B/hu unknown
- 1975-06-19 SU SU7502145925A patent/SU578880A3/ru active
- 1975-06-20 NL NL7507422A patent/NL7507422A/xx not_active Application Discontinuation
- 1975-06-20 ES ES438757A patent/ES438757A1/es not_active Expired
-
1979
- 1979-01-25 SE SE7900681A patent/SE7900681L/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2951247A1 (de) * | 1978-12-20 | 1980-07-03 | Science Union & Cie | N-substituierte trifluoraethylamine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
Also Published As
| Publication number | Publication date |
|---|---|
| IE41382B1 (en) | 1979-12-19 |
| AT342046B (de) | 1978-03-10 |
| FR2275207A1 (fr) | 1976-01-16 |
| AU497501B2 (en) | 1978-12-14 |
| ES438757A1 (es) | 1977-03-16 |
| ZA753943B (en) | 1976-06-30 |
| ATA471675A (de) | 1977-07-15 |
| BE830442A (fr) | 1975-12-19 |
| SU578880A3 (ru) | 1977-10-30 |
| FR2275207B1 (enrdf_load_stackoverflow) | 1979-08-10 |
| DE2526965A1 (de) | 1976-01-02 |
| SE7900681L (sv) | 1979-01-25 |
| HU173390B (hu) | 1979-04-28 |
| IE41382L (en) | 1975-12-20 |
| DK274375A (enrdf_load_stackoverflow) | 1975-12-21 |
| JPS5116662A (enrdf_load_stackoverflow) | 1976-02-10 |
| DK136313C (enrdf_load_stackoverflow) | 1978-02-20 |
| SE7507018L (sv) | 1975-12-22 |
| CA1062265A (fr) | 1979-09-11 |
| JPS5231341B2 (enrdf_load_stackoverflow) | 1977-08-13 |
| DK136313B (da) | 1977-09-26 |
| CH597206A5 (enrdf_load_stackoverflow) | 1978-03-31 |
| FI751825A7 (enrdf_load_stackoverflow) | 1975-12-21 |
| AU8224675A (en) | 1976-12-23 |
| NL7507422A (nl) | 1975-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |