IE41382L - Oxazoline derivatives. - Google Patents
Oxazoline derivatives.Info
- Publication number
- IE41382L IE41382L IE751361A IE136175A IE41382L IE 41382 L IE41382 L IE 41382L IE 751361 A IE751361 A IE 751361A IE 136175 A IE136175 A IE 136175A IE 41382 L IE41382 L IE 41382L
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- compound
- lower alkyl
- radical
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1475513 Oxazolines SCIENCE UNION ET CIE SOC FRANCAISE DE RECHERCHE MEDICALE 20 June 1975 [20 June 1974] 27392/74 Heading C2C Novel compounds of Formula I in which X is a hydrogen or halogen atom or a trifluoromethyl radical, R 1 is a lower alkyl radical or a lower cycloalkyl radical, R 2 is a hydrogen atom or a lower alkyl radical, and R 3 and R 4 , which may be the same or different, are hydrogen atoms or lower alkyl radicals or together form an alkylene group having from 3 to 6 carbon atoms where "lower" denotes group containing up to 6 carbon atoms on salts thereof are prepared by cyclization of a compound of Formula II #-Haloethyl urens of Formula II above are prepared by reacting a compound of Formula III with a compound of formula Starting materials of Formula III are obtained by reduction of an oxime formed from an R 1 COPh(X)CF 3 ketone or by reaction of cyanogen bromide with the alcohol obtained by reduction of such a ketone. Pharmaceutical compositions in conventional forms for buccil, rectal, sublingual or parenteral administration and having anti-hypertensive activity comprises an above novel compound and a carrier or diluent.
[GB1475513A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2739274A GB1475513A (en) | 1974-06-20 | 1974-06-20 | Benzylamine derivatives process for science union et cie benzylamine derivatives process for their production and pharmaceutical compositions containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
IE41382L true IE41382L (en) | 1975-12-20 |
IE41382B1 IE41382B1 (en) | 1979-12-19 |
Family
ID=10258850
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1361/75A IE41382B1 (en) | 1974-06-20 | 1975-06-17 | Benzylamine derivatives process for their production and pharmaceutical compositions containing them |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS5231341B2 (en) |
AT (1) | AT342046B (en) |
AU (1) | AU497501B2 (en) |
BE (1) | BE830442A (en) |
CA (1) | CA1062265A (en) |
CH (1) | CH597206A5 (en) |
DE (1) | DE2526965A1 (en) |
DK (1) | DK136313B (en) |
ES (1) | ES438757A1 (en) |
FI (1) | FI751825A (en) |
FR (1) | FR2275207A1 (en) |
GB (1) | GB1475513A (en) |
HU (1) | HU173390B (en) |
IE (1) | IE41382B1 (en) |
NL (1) | NL7507422A (en) |
SE (2) | SE7507018L (en) |
SU (1) | SU578880A3 (en) |
ZA (1) | ZA753943B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2358890A1 (en) * | 1976-05-24 | 1978-02-17 | Science Union & Cie | NEW ARYL TRIFLUOROETHYLAMINES, THEIR METHODS OF OBTAINING AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING |
JPS53105752U (en) * | 1977-01-31 | 1978-08-25 | ||
JPS5495252A (en) * | 1978-01-11 | 1979-07-27 | Oki Electric Ind Co Ltd | Thermal printer |
FR2444673A1 (en) * | 1978-12-20 | 1980-07-18 | Science Union & Cie | NOVEL TRIFLUOROETHYLAMINES, PROCESSES FOR OBTAINING SAME AND THEIR USE AS MEDICAMENTS |
JPS57136755U (en) * | 1981-02-20 | 1982-08-26 | ||
AUPP020297A0 (en) * | 1997-11-05 | 1997-11-27 | University Of Melbourne, The | A novel receptor, and compounds which bind thereto |
-
1974
- 1974-06-20 GB GB2739274A patent/GB1475513A/en not_active Expired
-
1975
- 1975-06-13 CA CA229,350A patent/CA1062265A/en not_active Expired
- 1975-06-16 DE DE19752526965 patent/DE2526965A1/en active Pending
- 1975-06-17 IE IE1361/75A patent/IE41382B1/en unknown
- 1975-06-18 DK DK274375AA patent/DK136313B/en unknown
- 1975-06-18 SE SE7507018A patent/SE7507018L/en unknown
- 1975-06-18 FI FI751825A patent/FI751825A/fi not_active Application Discontinuation
- 1975-06-19 JP JP50074996A patent/JPS5231341B2/ja not_active Expired
- 1975-06-19 ZA ZA00753943A patent/ZA753943B/en unknown
- 1975-06-19 SU SU7502145925A patent/SU578880A3/en active
- 1975-06-19 HU HU75SI1474A patent/HU173390B/en unknown
- 1975-06-19 BE BE157510A patent/BE830442A/en unknown
- 1975-06-19 AT AT471675A patent/AT342046B/en not_active IP Right Cessation
- 1975-06-19 FR FR7519164A patent/FR2275207A1/en active Granted
- 1975-06-19 CH CH801275A patent/CH597206A5/xx not_active IP Right Cessation
- 1975-06-19 AU AU82246/75A patent/AU497501B2/en not_active Expired
- 1975-06-20 ES ES438757A patent/ES438757A1/en not_active Expired
- 1975-06-20 NL NL7507422A patent/NL7507422A/en not_active Application Discontinuation
-
1979
- 1979-01-25 SE SE7900681A patent/SE7900681L/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE2526965A1 (en) | 1976-01-02 |
FR2275207B1 (en) | 1979-08-10 |
AT342046B (en) | 1978-03-10 |
ATA471675A (en) | 1977-07-15 |
IE41382B1 (en) | 1979-12-19 |
AU497501B2 (en) | 1978-12-14 |
CA1062265A (en) | 1979-09-11 |
HU173390B (en) | 1979-04-28 |
ZA753943B (en) | 1976-06-30 |
FR2275207A1 (en) | 1976-01-16 |
CH597206A5 (en) | 1978-03-31 |
DK136313C (en) | 1978-02-20 |
GB1475513A (en) | 1977-06-01 |
SU578880A3 (en) | 1977-10-30 |
SE7900681L (en) | 1979-01-25 |
JPS5116662A (en) | 1976-02-10 |
BE830442A (en) | 1975-12-19 |
NL7507422A (en) | 1975-12-23 |
DK274375A (en) | 1975-12-21 |
AU8224675A (en) | 1976-12-23 |
JPS5231341B2 (en) | 1977-08-13 |
FI751825A (en) | 1975-12-21 |
SE7507018L (en) | 1975-12-22 |
ES438757A1 (en) | 1977-03-16 |
DK136313B (en) | 1977-09-26 |
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