GB1460631A - Method and apparatus for immunoassay with regeneration of immunadsorbent - Google Patents

Method and apparatus for immunoassay with regeneration of immunadsorbent

Info

Publication number
GB1460631A
GB1460631A GB1147374A GB1147374A GB1460631A GB 1460631 A GB1460631 A GB 1460631A GB 1147374 A GB1147374 A GB 1147374A GB 1147374 A GB1147374 A GB 1147374A GB 1460631 A GB1460631 A GB 1460631A
Authority
GB
United Kingdom
Prior art keywords
antibody
antigen
immobilized
immobilized antibody
beads
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1147374A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Summa Corp
Original Assignee
Summa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Summa Corp filed Critical Summa Corp
Publication of GB1460631A publication Critical patent/GB1460631A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/826—Additives, e.g. buffers, diluents, preservatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB1147374A 1973-03-19 1974-03-14 Method and apparatus for immunoassay with regeneration of immunadsorbent Expired GB1460631A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US342513A US3896217A (en) 1973-03-19 1973-03-19 Method and apparatus for radioimmunoassay with regeneration of immunoadsorbent
US05/565,848 US4059685A (en) 1973-03-19 1975-04-07 Immobilized immunoadsorbent

Publications (1)

Publication Number Publication Date
GB1460631A true GB1460631A (en) 1977-01-06

Family

ID=26993049

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1147374A Expired GB1460631A (en) 1973-03-19 1974-03-14 Method and apparatus for immunoassay with regeneration of immunadsorbent

Country Status (5)

Country Link
US (2) US3896217A (enExample)
DE (2) DE2412833A1 (enExample)
FR (2) FR2222654B1 (enExample)
GB (1) GB1460631A (enExample)
NL (2) NL176307C (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2432171A1 (fr) * 1978-06-20 1980-02-22 Damon Corp Procede et necessaire utilisant des microcapsules semi-permeables pour la determination d'une substance biologiquement active et libre
US4271140A (en) * 1978-01-23 1981-06-02 Baxter Travenol Laboratories, Inc. Method and composition for double receptor, specific binding assays
WO1985003355A1 (en) * 1984-01-25 1985-08-01 Syn-Tek Ab A method of concentrating and detecting biomolecules and -cells and a means therefore
USRE34394E (en) * 1978-01-23 1993-09-28 Baxter Diagnostics Inc. Method and composition for double receptor, specific binding assays

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US4264766A (en) * 1877-09-19 1981-04-28 Hoffmann-La Roche Inc. Immunological diagnostic reagents
US3896217A (en) * 1973-03-19 1975-07-22 Summa Corp Method and apparatus for radioimmunoassay with regeneration of immunoadsorbent
GB1524372A (en) * 1975-01-09 1978-09-13 Radiochemical Centre Ltd Radioassay of oestrogens
NL7501215A (nl) * 1975-02-01 1976-08-03 Akzo Nv Methode voor het aantonen en bepalen van een antigeen of antilichaam.
US4166102A (en) * 1975-04-07 1979-08-28 Becton, Dickinson And Company Immobilized immunoadsorbent
US4041146A (en) * 1975-05-01 1977-08-09 General Electric Company Method for detection of biological particles
US4092408A (en) * 1975-08-28 1978-05-30 New England Nuclear Corporation Method for solid phase immunological assay of antigen
US4016043A (en) * 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
USRE32696E (en) * 1975-09-04 1988-06-14 Akzona Incorporated Enzymatic immunological method for determination of antigens and antibodies
US4474878A (en) * 1975-09-29 1984-10-02 Cordis Laboratories, Inc. Sandwich EIA for antigen associated with hepatitis
US4642285A (en) * 1975-09-29 1987-02-10 Diamedix Corporation Sandwich EIA for antigen
US4034071A (en) * 1976-01-26 1977-07-05 Allegheny General Hospital Immunoassay procedures
US4104026A (en) * 1976-03-12 1978-08-01 University Of Virginia Immunoassay separation technique
US4128628A (en) * 1976-03-12 1978-12-05 University Of Virginia Alumni Patents Foundation Automated immunoassay
US4081245A (en) * 1976-05-03 1978-03-28 Beckman Instruments, Inc. Immunoassay procedure employing novel immunochemical composites
US4081244A (en) * 1976-05-03 1978-03-28 Beckman Instruments, Inc. Immunoassay procedure employing novel immunochemical composites
US4081246A (en) * 1976-05-03 1978-03-28 Beckman Instruments, Inc. Solid phase column immunoassay procedure employing novel immunochemical composites
US4067959A (en) * 1976-05-10 1978-01-10 International Diagnostic Technology, Inc. Indirect solid surface test for antigens or antibodies
AT357272B (de) * 1976-09-18 1980-06-25 Boehringer Mannheim Gmbh Verfahren und vorrichtung zum nachweis und zur bestimmung eines spezifischen bindeproteins oder einer damit bindefaehigen substanz
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4108976A (en) * 1977-03-04 1978-08-22 Becton, Dickinson And Company Automated direct serum radioimmunoassay
US4268494A (en) * 1977-03-04 1981-05-19 Becton Dickinson & Company Automated direct serum radioassay
SE404553B (sv) * 1977-03-04 1978-10-09 Pharmacia Diagnostics Ab Sett vid bestemningsmetoder involverande biospecifika affinitetsreaktioner
US4108975A (en) * 1977-03-04 1978-08-22 Becton, Dickinson And Company Radioimmunoassay system
US4197287A (en) * 1977-06-10 1980-04-08 Ventrex Laboratories Inc. Method and apparatus for performing in nitro clinical diagnostic tests using a solid phase assay system having special utility for use with automatic pipetting equipment
CH628738A5 (de) * 1977-08-03 1982-03-15 Hoffmann La Roche Immunologisches diagnose-reagenz.
EP0001223A3 (en) * 1977-09-19 1979-12-12 F.Hoffmann-La Roche & Co. Aktiengesellschaft Latex coated with a polyhydroxy compound, process for the preparation of this latex, immunological reagent containing this latex, process for the preparation of this reagent, application of this reagent, testing procedure utilising this reagent and reagent kit containing this reagent
FR2403098A1 (fr) * 1977-09-19 1979-04-13 Merieux Inst Nouveau materiau capable de fixer de facon reversible des macromolecules biologiques, sa preparation et son application
JPS608745B2 (ja) * 1978-02-14 1985-03-05 三洋化成工業株式会社 免疫活性物質−つや消しガラス複合体，その製造法及び該複合体を含有してなる測定試薬
US4244694A (en) * 1978-03-31 1981-01-13 Union Carbide Corporation Reactor/separator device for use in automated solid phase immunoassay
US4275149A (en) * 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
FR2430013A1 (fr) * 1978-06-27 1980-01-25 Sebia Sa Systeme physico-biochimique pour la detection des substances, a activite antigenique
US4200625A (en) * 1978-07-12 1980-04-29 Becton, Dickinson And Company Immobilized binder for automated assay
US4238471A (en) * 1978-07-12 1980-12-09 Becton, Dickinson And Company Assay for thyroid hormone binding capacity
DE2836046A1 (de) * 1978-08-17 1980-02-28 Behringwerke Ag Immunologisches bestimmungsverfahren
US4278651A (en) * 1978-09-27 1981-07-14 Becton Dickinson & Company Supported receptor and use thereof in an assay
US4374925A (en) * 1978-11-24 1983-02-22 Syva Company Macromolecular environment control in specific receptor assays
US4318707A (en) * 1978-11-24 1982-03-09 Syva Company Macromolecular fluorescent quencher particle in specific receptor assays
US4238472A (en) * 1978-11-27 1980-12-09 United States Of America Radioimmunoassay for chlorinated dibenzo-p-dioxins
US4378344A (en) * 1979-09-28 1983-03-29 Ventrex Laboratories, Inc. Method and apparatus for performing multiple, simultaneous in vitro diagnostic tests using a solid phase system
AU6452480A (en) 1979-11-13 1982-05-27 Ventrex Laboratories Inc. Apparatus for carrying out solid phase in vitro diagnostic assays
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US4687808A (en) * 1982-08-12 1987-08-18 Biospecific Technologies, Inc. Activation of biocompatible polymers with biologicals whose binding complements are pathological effectors
US4737544A (en) * 1982-08-12 1988-04-12 Biospecific Technologies, Inc. Biospecific polymers
US4634417A (en) * 1982-12-06 1987-01-06 Georgetown University Process for treatment of tumors and apparatus therefor
US4994373A (en) 1983-01-27 1991-02-19 Enzo Biochem, Inc. Method and structures employing chemically-labelled polynucleotide probes
WO1984003358A1 (en) * 1983-02-25 1984-08-30 Covalent Technology Corp Insoluble surfaces treated to inhibit non-specific protein binding
WO1984004170A1 (en) * 1983-04-18 1984-10-25 Quidel Protection of antibody during chemical modification
EP0141818A1 (en) * 1983-04-18 1985-05-22 Quidel Removal of self-binding and staph a cross-reactivity of anti-strep antibody
US4666866A (en) * 1983-04-19 1987-05-19 Krauth Gary H Immunoassay for antigens employing supported binder
CA1236738A (en) * 1983-06-01 1988-05-17 Mark R. Honard Therapeutic device
US4685900A (en) * 1983-06-01 1987-08-11 Biospecific Technologies, Inc. Therapeutic device
US4615984A (en) * 1984-02-23 1986-10-07 Becton Dickinson & Company Dissociation of ligand-binder complex using ultrasound
US4840892A (en) * 1984-05-15 1989-06-20 Smithkline Beckman Corporation Polynucleotide hybridization probes
US4657869A (en) * 1984-05-18 1987-04-14 E. I. Du Pont De Nemours And Company Self-contained device for carrying out specific binding assays
DE3435744C2 (de) * 1984-09-28 1986-08-07 Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft mbH, 6900 Heidelberg Trägermaterial zur Verwendung für Immunbestimmungen
US4703018A (en) * 1985-02-20 1987-10-27 E. I. Du Pont De Nemours And Company High refractive index haloalkyl-functional shell-core polymers and their use in light scattering immunoassays
EP0194988A1 (fr) * 1985-03-14 1986-09-17 Bertrand, Alain Support pour tests de laboratoire
DE3664729D1 (en) * 1985-04-09 1989-09-07 Terumo Corp Immunoglobulin adsorbent and adsorption apparatus
US4752572A (en) * 1985-08-30 1988-06-21 Eastman Kodak Company Lipid vesicles containing labeled species and their analytical uses
DK289686A (da) * 1986-06-19 1987-12-20 Immuntech As Fremgangsmaade til fremstilling af overfladebaserede immunanalyser
US4762787A (en) * 1986-11-21 1988-08-09 Imre Corporation Anti-human IGM immunoadsorbent and process for producing said immunoadsorbent
US4863869A (en) * 1986-11-21 1989-09-05 Imre Cororation Anti-human IGM immunoadsorbent and process for producing said immunoadsorbent
US5073344A (en) * 1987-07-17 1991-12-17 Porex Technologies Corp. Diagnostic system employing a unitary substrate to immobilize microspheres
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5137804A (en) * 1988-05-10 1992-08-11 E. I. Du Pont De Nemours And Company Assay device and immunoassay
US5389523A (en) * 1988-05-31 1995-02-14 The United States Of Americas, As Represented By The Secretary Of Commerce Liposome immunoanalysis by flow injection assay
US5686579A (en) * 1988-06-21 1997-11-11 Hybrisens, Ltd. Use of antibody/antigen interactions to protect biologically active proteins and peptides
FR2635019B1 (fr) * 1988-08-02 1992-06-12 Centre Nat Rech Scient Materiau capable de fixer les substances biologiques, et ses applications notamment comme support de chromatographie d'affinite
US5162218A (en) * 1988-11-18 1992-11-10 The Regents Of The University Of California Conjugated polypeptides and methods for their preparation
JPH04504713A (ja) * 1988-11-18 1992-08-20 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 共役ポリペプチドとその調製および使用方法
JPH04504199A (ja) * 1989-02-03 1992-07-30 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション 単クローン性抗体およびその用途
US5308771A (en) * 1992-04-13 1994-05-03 Geo-Centers, Inc. Chemical sensors
US6664114B1 (en) * 1992-08-03 2003-12-16 Sapidyne Instruments, Inc. Solid phase assay for detection of ligands
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AT279804B (de) * 1967-08-22 1970-03-25 Barbara Dr Polheim Verfahren zur Isolierung von Antigenen und Antikörpern
US3592888A (en) * 1968-01-19 1971-07-13 Mount Sinai Hospital Research Radioimmunoassay of angiotensin and renin activity
US3639558A (en) * 1968-02-19 1972-02-01 Louis Csizmas Immunological reagent particles having proteinaceous materials covalently bonded thereto
CH564031A5 (enExample) * 1968-03-29 1975-07-15 Anvar
US3720760A (en) * 1968-09-06 1973-03-13 Pharmacia Ab Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples
US3652761A (en) * 1969-09-04 1972-03-28 Corning Glass Works Immunochemical composites and antigen or antibody purification therewith
US3796634A (en) * 1970-03-19 1974-03-12 Us Health Education & Welfare Insolubilized biologically active enzymes
US3896217A (en) * 1973-03-19 1975-07-22 Summa Corp Method and apparatus for radioimmunoassay with regeneration of immunoadsorbent
US3975511A (en) * 1974-03-01 1976-08-17 Corning Glass Works Solid phase radioimmunoassay

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271140A (en) * 1978-01-23 1981-06-02 Baxter Travenol Laboratories, Inc. Method and composition for double receptor, specific binding assays
USRE34394E (en) * 1978-01-23 1993-09-28 Baxter Diagnostics Inc. Method and composition for double receptor, specific binding assays
FR2432171A1 (fr) * 1978-06-20 1980-02-22 Damon Corp Procede et necessaire utilisant des microcapsules semi-permeables pour la determination d'une substance biologiquement active et libre
US4822732A (en) * 1984-01-24 1989-04-18 Sandstroem Gunnar Method of concentrating and detecting biomolecules and cells
WO1985003355A1 (en) * 1984-01-25 1985-08-01 Syn-Tek Ab A method of concentrating and detecting biomolecules and -cells and a means therefore
EP0153283A1 (en) * 1984-01-25 1985-08-28 Symbicom Ab A method of concentrating and detecting biomolecules and -cells
AU589890B2 (en) * 1984-01-25 1989-10-26 Symbicom Aktiebolag A method of concentrating and detecting biomolecules and -cells and a means therefore

Also Published As

Publication number Publication date
DE2612948A1 (de) 1976-10-21
NL176307B (nl) 1984-10-16
DE2412833A1 (de) 1974-10-03
FR2222654A1 (enExample) 1974-10-18
FR2222654B1 (enExample) 1977-09-30
NL176307C (nl) 1985-03-18
FR2307268B1 (enExample) 1980-03-28
NL7603439A (nl) 1976-10-11
US3896217A (en) 1975-07-22
FR2307268A1 (fr) 1976-11-05
US4059685A (en) 1977-11-22
NL7403215A (enExample) 1974-09-23
DE2612948C2 (de) 1981-11-26

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee