GB1455529A - - Google Patents
Info
- Publication number
- GB1455529A GB1455529A GB818675A GB818675A GB1455529A GB 1455529 A GB1455529 A GB 1455529A GB 818675 A GB818675 A GB 818675A GB 818675 A GB818675 A GB 818675A GB 1455529 A GB1455529 A GB 1455529A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- mono
- acid chloride
- salts
- thienylmalonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- IWDCLRJOBJJRNH-UHFFFAOYSA-N p-cresol Chemical compound CC1=CC=C(O)C=C1 IWDCLRJOBJJRNH-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- GCOOGCQWQFRJEK-UHFFFAOYSA-N 2-thiophen-3-ylpropanedioic acid Chemical compound OC(=O)C(C(O)=O)C=1C=CSC=1 GCOOGCQWQFRJEK-UHFFFAOYSA-N 0.000 abstract 1
- CUVRDWCJNCFUDT-UHFFFAOYSA-N 3-(4-methylphenoxy)-3-oxo-2-thiophen-3-ylpropanoic acid Chemical compound CC1=CC=C(C=C1)OC(=O)C(C2=CSC=C2)C(=O)O CUVRDWCJNCFUDT-UHFFFAOYSA-N 0.000 abstract 1
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 1
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB818675A GB1455529A (enrdf_load_stackoverflow) | 1975-02-27 | 1975-02-27 | |
| CA228,020A CA1047484A (en) | 1975-02-27 | 1975-05-29 | Penicillins |
| ZA757369A ZA757369B (en) | 1975-02-27 | 1975-11-24 | Penicillins |
| DE19752555158 DE2555158A1 (de) | 1975-02-27 | 1975-12-08 | Alpha-(tolyloxycarbonyl)-3-thienylmethylpenicillin, verfahren zu seiner herstellung und diese verbindung enthaltende arzneipraeparate |
| JP51011179A JPS51101993A (enrdf_load_stackoverflow) | 1975-02-27 | 1976-02-04 | |
| AU11462/76A AU1146276A (en) | 1975-02-27 | 1976-02-26 | Penicillins |
| ES445577A ES445577A1 (es) | 1975-02-27 | 1976-02-26 | Un procedimiento para la preparacion de alfa-(toliloxicarbo-nil)-3-tienilmetilpenicilina. |
| BE164751A BE839058A (fr) | 1975-02-27 | 1976-02-27 | Penicillines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB818675A GB1455529A (enrdf_load_stackoverflow) | 1975-02-27 | 1975-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1455529A true GB1455529A (enrdf_load_stackoverflow) | 1976-11-10 |
Family
ID=9847499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB818675A Expired GB1455529A (enrdf_load_stackoverflow) | 1975-02-27 | 1975-02-27 |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS51101993A (enrdf_load_stackoverflow) |
| AU (1) | AU1146276A (enrdf_load_stackoverflow) |
| BE (1) | BE839058A (enrdf_load_stackoverflow) |
| CA (1) | CA1047484A (enrdf_load_stackoverflow) |
| DE (1) | DE2555158A1 (enrdf_load_stackoverflow) |
| ES (1) | ES445577A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1455529A (enrdf_load_stackoverflow) |
| ZA (1) | ZA757369B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0026644A1 (en) * | 1979-10-02 | 1981-04-08 | Beecham Group Plc | Ortho-tolyl ester of an alpha-carboxy penicillin, process for its preparation and pharmaceutical compositions comprising the penicillin |
-
1975
- 1975-02-27 GB GB818675A patent/GB1455529A/en not_active Expired
- 1975-05-29 CA CA228,020A patent/CA1047484A/en not_active Expired
- 1975-11-24 ZA ZA757369A patent/ZA757369B/xx unknown
- 1975-12-08 DE DE19752555158 patent/DE2555158A1/de active Pending
-
1976
- 1976-02-04 JP JP51011179A patent/JPS51101993A/ja active Pending
- 1976-02-26 ES ES445577A patent/ES445577A1/es not_active Expired
- 1976-02-26 AU AU11462/76A patent/AU1146276A/en not_active Expired
- 1976-02-27 BE BE164751A patent/BE839058A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0026644A1 (en) * | 1979-10-02 | 1981-04-08 | Beecham Group Plc | Ortho-tolyl ester of an alpha-carboxy penicillin, process for its preparation and pharmaceutical compositions comprising the penicillin |
| US4385060A (en) | 1979-10-02 | 1983-05-24 | Beecham Group Limited | Penicillins |
Also Published As
| Publication number | Publication date |
|---|---|
| ES445577A1 (es) | 1977-11-01 |
| AU1146276A (en) | 1977-09-01 |
| JPS51101993A (enrdf_load_stackoverflow) | 1976-09-08 |
| CA1047484A (en) | 1979-01-30 |
| BE839058A (fr) | 1976-08-27 |
| ZA757369B (en) | 1976-11-24 |
| DE2555158A1 (de) | 1976-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |