FR2378762A2 - Amides aromatiques de composes heterocycliques et leur application en tant que medicament - Google Patents
Amides aromatiques de composes heterocycliques et leur application en tant que medicamentInfo
- Publication number
- FR2378762A2 FR2378762A2 FR7733111A FR7733111A FR2378762A2 FR 2378762 A2 FR2378762 A2 FR 2378762A2 FR 7733111 A FR7733111 A FR 7733111A FR 7733111 A FR7733111 A FR 7733111A FR 2378762 A2 FR2378762 A2 FR 2378762A2
- Authority
- FR
- France
- Prior art keywords
- methoxy
- chlorobenzamide
- ylõ
- piperid
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente addition concerne les produits suivants : le N-Ø1-(m-trifluorométhylbenzyl)pipérid-4-ylõ -2-méthoxy-4-amino-5-chlorobenzamide, le N-Ø1-(1-phényléthyl)pipérid-4-ylõ - 2-éthoxy-4-amino-5-chlorobenzamide, le N- Ø1-(2-méthoxy-5-chlorobenzyl)pipérid-4-ylõ -2-méthoxy-4-amino-5-chlorobenzamide, le N Ø1- beta -naphtylméthyl) pipérid-4-ylõ-2-méthoxy-4-amino-5-chlorobenzamide, le N-Ø1-(p-méthyl-benzyl)pipérid-4-ylõ-2-méthoxy-4-amino-5-chlorobenzamide, le N-Ø1-p-bromobenzyl)-pipérid-4-ylõ -2-méthoxy-4-amino-5-chlorobenzamide, le N-Ø1-(p-fluorobenzyl)pipérid-4-ylõ-2-méthoxy-4-amino-5-chlorobenzamide, le N-Ø1-(p-méthylbenzyl)pipérid-4-ylõ -2- méthoxy-4-amino-5-chlorobenzamide, le N-(1-benzylpérid-4-yl)-2-méthoxy-4,5-diaminobenzamide, le N-Ø1-(p-nitrobenzyl)-pipérid-4-ylõ-2-méthoxy-4-amino-5-chlorobenzamide, le N-Ø1-(1-phénylethyl)pipérid-4-ylõ-2-méthoxy-4-amino-5-bromobenzamide, le N-Ø1-(m-méthylbenzyl)pipérid-4-ylõ-2-méthoxy-4-amino-5-chlorobenzamide, le N-(1-benzylpipérid-4-yl)-2-méthoxy-4-amino-5-chlorobenzamide, le N-Ø1-1-phényléthyl)-pipérid-4-ylõ-2-méthoxy-4,5-diamino-benzamide, le N-(1-benzypipérid-4-yl)-2-méthoxy -4-diméthylamino -5-chlorobenzamide, le N-Ø1-(1-phényléthyl)pipérid-4-ylõ -2-méthoxy-4-acétamido-5-aminobenzamide, le N-(1-benzylpipérid)2-méthoxy-4-méthylamino-5-chlorobenzamide, le N-(1-benzylpyérid-4-yl)-2-allyloxy-4-amino-5-chlorobenzamide, le N-(1-p-methylbenzylpipérid-4-yl)-2-méthoxy-4-acétamido-5-aminobenzamide, le N-(1-benzylpipérid-4-yl) -2-méthoxy -4-acétamido-5-aminobenzamide, le N-Ø1-(2-méthoxy-5-chloro-benzyl) -pipérid-4-ylõ -2-méthoxy-4-acétamido-5-aminobenzamide et le N-(1-benzylpipérid-4-yl)-2-éthoxy-4-méthylamino-5-chlorobenzamide ainsi que les sels pharmaceutiquement acceptables de ces composés. Ces composés présentent une activité intéressante vis-à-vis de l'anorexie, de la vasodilatation, de l'inhibition de sécrétion d'acide gastrique et de la formation d'ulcères.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4464976A GB1593851A (en) | 1976-10-27 | 1976-10-27 | N-(4-piperidyl)-benzamides and pharmaceutical compositions containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2378762A2 true FR2378762A2 (fr) | 1978-08-25 |
FR2378762B2 FR2378762B2 (fr) | 1980-09-12 |
Family
ID=10434204
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7733111A Granted FR2378762A2 (fr) | 1976-10-27 | 1977-10-26 | Amides aromatiques de composes heterocycliques et leur application en tant que medicament |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5392783A (fr) |
BE (1) | BE860139R (fr) |
CA (1) | CA1085855A (fr) |
CH (1) | CH625219A5 (fr) |
ES (1) | ES463557A2 (fr) |
FR (1) | FR2378762A2 (fr) |
GB (1) | GB1593851A (fr) |
NL (1) | NL7711690A (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001036385A1 (fr) * | 1999-11-17 | 2001-05-25 | Kissei Pharmaceutical Co., Ltd. | Derives hydroxyethoxybenzamides et medicaments les contenant |
TW200800953A (en) | 2002-10-30 | 2008-01-01 | Theravance Inc | Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine |
US7368463B2 (en) | 2003-07-11 | 2008-05-06 | Theravance, Inc. | Substituted 4-amino-1-benzylpiperidine compounds |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR5916M (fr) * | 1966-01-21 | 1968-05-06 | ||
FR2105223A1 (fr) * | 1970-09-03 | 1972-04-28 | Wyeth John & Brother Ltd |
-
1976
- 1976-10-27 GB GB4464976A patent/GB1593851A/en not_active Expired
-
1977
- 1977-10-25 CH CH1295177A patent/CH625219A5/fr not_active IP Right Cessation
- 1977-10-25 NL NL7711690A patent/NL7711690A/xx not_active Application Discontinuation
- 1977-10-26 CA CA289,550A patent/CA1085855A/fr not_active Expired
- 1977-10-26 FR FR7733111A patent/FR2378762A2/fr active Granted
- 1977-10-26 ES ES463557A patent/ES463557A2/es not_active Expired
- 1977-10-26 BE BE182086A patent/BE860139R/fr not_active IP Right Cessation
- 1977-10-27 JP JP12915777A patent/JPS5392783A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR5916M (fr) * | 1966-01-21 | 1968-05-06 | ||
FR2105223A1 (fr) * | 1970-09-03 | 1972-04-28 | Wyeth John & Brother Ltd |
Also Published As
Publication number | Publication date |
---|---|
FR2378762B2 (fr) | 1980-09-12 |
GB1593851A (en) | 1981-07-22 |
CA1085855A (fr) | 1980-09-16 |
ES463557A2 (es) | 1978-11-16 |
BE860139R (fr) | 1978-02-15 |
CH625219A5 (en) | 1981-09-15 |
JPS5392783A (en) | 1978-08-15 |
NL7711690A (nl) | 1978-05-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name |