FR2105223A1 - - Google Patents
Info
- Publication number
- FR2105223A1 FR2105223A1 FR7131823A FR7131823A FR2105223A1 FR 2105223 A1 FR2105223 A1 FR 2105223A1 FR 7131823 A FR7131823 A FR 7131823A FR 7131823 A FR7131823 A FR 7131823A FR 2105223 A1 FR2105223 A1 FR 2105223A1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4209070 | 1970-09-03 | ||
| GB3437671 | 1971-07-22 | ||
| US32368473A | 1973-01-15 | 1973-01-15 | |
| US524027A US3907810A (en) | 1970-09-03 | 1974-11-15 | 1-Imidazolylalkylene-piperidines |
| US524030A US3910932A (en) | 1970-09-03 | 1974-11-15 | 1-Pyridylalkyl piperidines |
| US524161A US3917614A (en) | 1970-09-03 | 1974-11-15 | 1-Pyrrolyl alkylene-piperidines |
| US524028A US3912741A (en) | 1970-09-03 | 1974-11-15 | 1-(Benzo{8 b{9 thienylalkyl)piperidines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2105223A1 true FR2105223A1 (fr) | 1972-04-28 |
| FR2105223B1 FR2105223B1 (fr) | 1975-10-10 |
Family
ID=27562647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7131823A Expired FR2105223B1 (fr) | 1970-09-03 | 1971-09-02 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US3917614A (fr) |
| AT (2) | AT316553B (fr) |
| AU (1) | AU461209B2 (fr) |
| BE (1) | BE772190A (fr) |
| CA (1) | CA955252A (fr) |
| CH (3) | CH593258A5 (fr) |
| DE (1) | DE2144080C2 (fr) |
| FR (1) | FR2105223B1 (fr) |
| GB (1) | GB1345872A (fr) |
| NL (1) | NL173954C (fr) |
| SE (1) | SE402284B (fr) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2187357A1 (fr) * | 1972-06-14 | 1974-01-18 | Sumitomo Chemical Co | |
| FR2378762A2 (fr) * | 1976-10-27 | 1978-08-25 | Anphar Sa | Amides aromatiques de composes heterocycliques et leur application en tant que medicament |
| WO1984000546A1 (fr) * | 1982-07-26 | 1984-02-16 | Bouchara Emile | Nouveaux derives substitues du 2,5-diamino 1,4-diazole, leurs procedes de preparation et les compositions pharmaceutiques en renfermant |
| EP0137163A2 (fr) * | 1983-09-14 | 1985-04-17 | Yoshitomi Pharmaceutical Industries, Ltd. | Dérivés de 3-indolecarboxamide |
| US4569933A (en) * | 1984-04-13 | 1986-02-11 | Cornu Pierre Jean | Antihypertensive substituted derivatives of 2,5-diamino 1,4-diazole |
| FR2813306A1 (fr) * | 2000-08-23 | 2002-03-01 | Sanofi Synthelabo | Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4028365A (en) * | 1970-09-03 | 1977-06-07 | John Wyeth & Brother Limited | Benz[g]indolyl compounds |
| US4046767A (en) * | 1970-09-03 | 1977-09-06 | John Wyeth & Brother Limited | Piperidino compounds |
| US4024147A (en) * | 1972-06-30 | 1977-05-17 | John Wyeth & Brother Limited | Heterocyclic compounds |
| US4061758A (en) * | 1972-06-30 | 1977-12-06 | John Wyeth & Brother Limited | Treating hypertension and central nervous system abnormalities |
| GB1459506A (en) * | 1974-02-18 | 1976-12-22 | Wyeth John & Brother Ltd | Piperidine derivatives |
| GB1507462A (en) * | 1974-03-21 | 1978-04-12 | Gallardo Antonio Sa | N-heterocyclic substituted benzamides methods for their preparation and compositions containing them |
| DE2513136C3 (de) * | 1974-03-21 | 1981-04-30 | Anphar S.A., Madrid | N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate |
| US4069331A (en) * | 1974-05-16 | 1978-01-17 | Boehringer Ingelheim Gmbh | N-(p-fluorobenzoyl-n-propyl)-4-piperidylamides and salts thereof |
| GB1498884A (en) * | 1975-04-15 | 1978-01-25 | Wyeth John & Brother Ltd | Aminoacetamide-pyridyl-tetrahydropyridyl and-piperidyl derivatives |
| US4191683A (en) * | 1975-05-28 | 1980-03-04 | Ciba-Geigy Corporation | Derivatives of 4-aminopiperidine as stabilizers for polymers |
| US4027028A (en) * | 1975-11-10 | 1977-05-31 | Science Union Et Cie | Arylethers and pharmaceutical compositions |
| US4163789A (en) * | 1976-02-17 | 1979-08-07 | Anphar, S.A. | Anti-psychotic (cycloalkenylalkylpiperidino) benzamides |
| GB1574418A (en) * | 1976-11-16 | 1980-09-03 | Anphar Sa | Piperidine derivatives |
| GB1582239A (en) * | 1976-12-11 | 1981-01-07 | Wyeth John & Brother Ltd | Piperidin-4-yl ureas and thioureas |
| US4962115A (en) * | 1981-10-01 | 1990-10-09 | Janssen Pharmaceutica N.V. | Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
| JPS60123485A (ja) * | 1983-12-08 | 1985-07-02 | Yoshitomi Pharmaceut Ind Ltd | インド−ル−３−カルボキサミド誘導体 |
| JPS60142981A (ja) * | 1983-12-28 | 1985-07-29 | Yoshitomi Pharmaceut Ind Ltd | ３−インド−ルカルボキサミド誘導体 |
| ZA86171B (en) * | 1985-01-16 | 1986-08-27 | Hoffmann La Roche | Polycyclic salts |
| JP2832979B2 (ja) * | 1988-02-15 | 1998-12-09 | 武田薬品工業株式会社 | 不飽和カルボン酸アミド誘導体 |
| US5280032A (en) * | 1989-02-14 | 1994-01-18 | Toyama Chemical Co., Ltd. | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same |
| US5210090A (en) * | 1989-09-05 | 1993-05-11 | G. D. Searle & Co. | Substituted N-benzylpiperidine amides and cardiac regulatory compositions thereof |
| US5028616A (en) * | 1989-09-05 | 1991-07-02 | G. D. Searle & Co. | N-benzylpiperidine amides |
| US5070094A (en) * | 1989-09-05 | 1991-12-03 | G. D. Searle & Co. | N-benzyltropaneamides |
| US4992446A (en) * | 1989-09-05 | 1991-02-12 | G. D. Searle & Co. | Tricyclic quinolizine amides |
| US5098915A (en) * | 1989-09-05 | 1992-03-24 | G. D. Searle & Co. | Substituted N-benzylpiperidine amides |
| US5053413A (en) * | 1989-09-05 | 1991-10-01 | G. D. Searle & Co. | N-benzylpiperidineisoindolinones |
| US5578611A (en) * | 1992-11-13 | 1996-11-26 | Synaptic Pharmaceutical Corporation | Use of α-1C specific compounds to treat benign prostatic hyperplasia |
| US6015819A (en) | 1992-11-13 | 2000-01-18 | Synaptic Pharmaceutical Corporation | Use of alpha-1C specific compounds to treat benign prostatic hyperplasia |
| US5403847A (en) * | 1992-11-13 | 1995-04-04 | Synaptic Pharmaceutical Corporation | Use of α1C specific compounds to treat benign prostatic hyperlasia |
| CA2149864A1 (fr) * | 1992-11-20 | 1994-06-09 | Nobuo Ishiyama | Derive de l'acetamide |
| AU2001289749B9 (en) | 2000-07-26 | 2004-08-19 | Smithkline Beecham P.L.C. | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity |
| GB0101577D0 (en) | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| AR038240A1 (es) | 2002-01-29 | 2005-01-05 | Glaxo Group Ltd | Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para su preparacion |
| EP1470131A2 (fr) | 2002-01-29 | 2004-10-27 | Glaxo Group Limited | Composes aminopiperidine, leur procede de preparation et compositions pharmaceutiques les contenant |
| WO2003076401A1 (fr) | 2002-03-13 | 2003-09-18 | Janssen Pharmaceutica N.V. | Derives d'amino-sulfonyle utilises comme inhibiteurs de l'histone deacetylase |
| CA2476067C (fr) | 2002-03-13 | 2011-09-20 | Janssen Pharmaceutica N.V. | Derives carbonylamino utilises en tant que nouveaux inhibiteurs d'histone deacetylase |
| KR20040090979A (ko) | 2002-03-13 | 2004-10-27 | 얀센 파마슈티카 엔.브이. | 히스톤 데아세틸레이즈의 신규한 억제제 |
| KR20040093692A (ko) | 2002-03-13 | 2004-11-08 | 얀센 파마슈티카 엔.브이. | 히스톤 디아세틸라제의 신규한 저해제로서의 피페라지닐-,피페리디닐- 및 모르폴리닐-유도체 |
| WO2006010750A1 (fr) | 2004-07-28 | 2006-02-02 | Janssen Pharmaceutica N.V. | Derives d'indolyl alkyl amine substitues utilises en tant que nouveaux inhibiteurs d'histone deacetylase |
| ES2553178T3 (es) | 2005-05-18 | 2015-12-04 | Janssen Pharmaceutica N.V. | Derivados sustituidos de aminopropenil piperidina o morfolina como nuevos inhibidores de histona deacetilasa |
| US8101616B2 (en) | 2006-01-19 | 2012-01-24 | Janssen Pharmaceutica N.V. | Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase |
| ES2327972T3 (es) | 2006-01-19 | 2009-11-05 | Janssen Pharmaceutica, N.V. | Derivados de aminofenil como nuevos inhibidores de histona deacetilasa. |
| EP1981875B1 (fr) | 2006-01-19 | 2014-04-16 | Janssen Pharmaceutica N.V. | Dérivés substitués d'indolyl-alkyl-amine en tant qu'inhibiteurs de l'histone désacétylase |
| DK1979326T3 (da) | 2006-01-19 | 2013-01-07 | Janssen Pharmaceutica Nv | Pyridin- og pyrimidinderivater som inhibitorer af histondeacetylase |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL267843A (fr) * | 1960-08-03 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270026A (en) * | 1963-07-03 | 1966-08-30 | Hoffmann La Roche | Substituted benzamidotetrahydro-pyridines and processes |
| GB1154744A (en) * | 1966-05-17 | 1969-06-11 | Whitefin Holding Sa | Disubstituted Aminoethanols |
| GB1221061A (en) * | 1967-01-18 | 1971-02-03 | May & Baker Ltd | Quaternary ammonium derivatives, their use as anthelmintics and methods for their preparation |
| US3855242A (en) * | 1967-12-15 | 1974-12-17 | Aspro Nicholas Ltd | Benzo{8 b{9 thienyl-alkyl-guanidines |
| DE2060816C3 (de) * | 1970-12-10 | 1980-09-04 | Merck Patent Gmbh, 6100 Darmstadt | 4-Phenylpiperidinderivate Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen enthaltend diese Verbindungen |
-
1970
- 1970-09-03 GB GB4209070A patent/GB1345872A/en not_active Expired
-
1971
- 1971-08-31 CA CA121,748A patent/CA955252A/en not_active Expired
- 1971-08-31 CH CH1280971A patent/CH593258A5/xx not_active IP Right Cessation
- 1971-08-31 CH CH1670775A patent/CH598218A5/xx not_active IP Right Cessation
- 1971-09-01 AT AT297873A patent/AT316553B/de not_active IP Right Cessation
- 1971-09-01 AT AT760671A patent/AT319239B/de not_active IP Right Cessation
- 1971-09-02 DE DE2144080A patent/DE2144080C2/de not_active Expired
- 1971-09-02 AU AU33005/71A patent/AU461209B2/en not_active Expired
- 1971-09-02 FR FR7131823A patent/FR2105223B1/fr not_active Expired
- 1971-09-03 SE SE7111236A patent/SE402284B/xx unknown
- 1971-09-03 BE BE772190A patent/BE772190A/fr not_active IP Right Cessation
- 1971-09-03 NL NLAANVRAGE7112176,A patent/NL173954C/xx not_active IP Right Cessation
-
1974
- 1974-11-15 US US524161A patent/US3917614A/en not_active Expired - Lifetime
- 1974-11-15 US US524027A patent/US3907810A/en not_active Expired - Lifetime
- 1974-11-15 US US524030A patent/US3910932A/en not_active Expired - Lifetime
- 1974-11-15 US US524028A patent/US3912741A/en not_active Expired - Lifetime
-
1975
- 1975-08-31 CH CH1670875A patent/CH598219A5/xx not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL267843A (fr) * | 1960-08-03 |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2187357A1 (fr) * | 1972-06-14 | 1974-01-18 | Sumitomo Chemical Co | |
| FR2378762A2 (fr) * | 1976-10-27 | 1978-08-25 | Anphar Sa | Amides aromatiques de composes heterocycliques et leur application en tant que medicament |
| WO1984000546A1 (fr) * | 1982-07-26 | 1984-02-16 | Bouchara Emile | Nouveaux derives substitues du 2,5-diamino 1,4-diazole, leurs procedes de preparation et les compositions pharmaceutiques en renfermant |
| EP0137163A2 (fr) * | 1983-09-14 | 1985-04-17 | Yoshitomi Pharmaceutical Industries, Ltd. | Dérivés de 3-indolecarboxamide |
| EP0137163A3 (fr) * | 1983-09-14 | 1987-04-15 | Yoshitomi Pharmaceutical Industries, Ltd. | Dérivés de 3-indolecarboxamide |
| US4569933A (en) * | 1984-04-13 | 1986-02-11 | Cornu Pierre Jean | Antihypertensive substituted derivatives of 2,5-diamino 1,4-diazole |
| FR2813306A1 (fr) * | 2000-08-23 | 2002-03-01 | Sanofi Synthelabo | Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
Also Published As
| Publication number | Publication date |
|---|---|
| AT319239B (de) | 1974-12-10 |
| CH598218A5 (fr) | 1978-04-28 |
| GB1345872A (en) | 1974-02-06 |
| CA955252A (en) | 1974-09-24 |
| NL173954B (nl) | 1983-11-01 |
| BE772190A (fr) | 1972-01-17 |
| CH593258A5 (fr) | 1977-11-30 |
| CH598219A5 (fr) | 1978-04-28 |
| DE2144080A1 (de) | 1972-03-09 |
| NL173954C (nl) | 1984-04-02 |
| AU461209B2 (en) | 1975-05-22 |
| AT316553B (de) | 1974-07-25 |
| FR2105223B1 (fr) | 1975-10-10 |
| SE402284B (sv) | 1978-06-26 |
| AU3300571A (en) | 1973-03-08 |
| DE2144080C2 (de) | 1983-12-08 |
| US3910932A (en) | 1975-10-07 |
| US3917614A (en) | 1975-11-04 |
| NL7112176A (fr) | 1972-03-07 |
| US3912741A (en) | 1975-10-14 |
| US3907810A (en) | 1975-09-23 |