BE772190A - Nouvelles compositions pharmaceutiques - Google Patents

Nouvelles compositions pharmaceutiques

Info

Publication number
BE772190A
BE772190A BE772190A BE772190A BE772190A BE 772190 A BE772190 A BE 772190A BE 772190 A BE772190 A BE 772190A BE 772190 A BE772190 A BE 772190A BE 772190 A BE772190 A BE 772190A
Authority
BE
Belgium
Prior art keywords
pharmaceutical compositions
new pharmaceutical
new
compositions
pharmaceutical
Prior art date
Application number
BE772190A
Other languages
English (en)
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of BE772190A publication Critical patent/BE772190A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
BE772190A 1970-09-03 1971-09-03 Nouvelles compositions pharmaceutiques BE772190A (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB4209070 1970-09-03
GB3437671 1971-07-22
US32368473A 1973-01-15 1973-01-15
US524030A US3910932A (en) 1970-09-03 1974-11-15 1-Pyridylalkyl piperidines
US524161A US3917614A (en) 1970-09-03 1974-11-15 1-Pyrrolyl alkylene-piperidines
US524027A US3907810A (en) 1970-09-03 1974-11-15 1-Imidazolylalkylene-piperidines
US524028A US3912741A (en) 1970-09-03 1974-11-15 1-(Benzo{8 b{9 thienylalkyl)piperidines

Publications (1)

Publication Number Publication Date
BE772190A true BE772190A (fr) 1972-01-17

Family

ID=27562647

Family Applications (1)

Application Number Title Priority Date Filing Date
BE772190A BE772190A (fr) 1970-09-03 1971-09-03 Nouvelles compositions pharmaceutiques

Country Status (11)

Country Link
US (4) US3912741A (fr)
AT (2) AT316553B (fr)
AU (1) AU461209B2 (fr)
BE (1) BE772190A (fr)
CA (1) CA955252A (fr)
CH (3) CH598218A5 (fr)
DE (1) DE2144080C2 (fr)
FR (1) FR2105223B1 (fr)
GB (1) GB1345872A (fr)
NL (1) NL173954C (fr)
SE (1) SE402284B (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028365A (en) * 1970-09-03 1977-06-07 John Wyeth & Brother Limited Benz[g]indolyl compounds
US4675328A (en) * 1985-01-16 1987-06-23 Hoffmann-Laroche Inc. Phenyl-pyridinium salts and use thereof in inhibiting intestinal resorption
US7109213B2 (en) 2002-01-29 2006-09-19 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US7205408B2 (en) 2001-01-22 2007-04-17 Smithkline Beecham, P.L.C. Quinolines and nitrogenated derivative thereof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents
US7312212B2 (en) 2002-01-29 2007-12-25 Glaxo Group Limited Aminopiperidine derivatives

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046767A (en) * 1970-09-03 1977-09-06 John Wyeth & Brother Limited Piperidino compounds
JPS5760335B2 (fr) * 1972-06-14 1982-12-18 Sumitomo Chemical Co
US4024147A (en) * 1972-06-30 1977-05-17 John Wyeth & Brother Limited Heterocyclic compounds
US4061758A (en) * 1972-06-30 1977-12-06 John Wyeth & Brother Limited Treating hypertension and central nervous system abnormalities
GB1459506A (en) * 1974-02-18 1976-12-22 Wyeth John & Brother Ltd Piperidine derivatives
DE2513136C3 (de) * 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
GB1593851A (en) * 1976-10-27 1981-07-22 Gallardo Antonio Sa N-(4-piperidyl)-benzamides and pharmaceutical compositions containing them
GB1507462A (en) * 1974-03-21 1978-04-12 Gallardo Antonio Sa N-heterocyclic substituted benzamides methods for their preparation and compositions containing them
US4069331A (en) * 1974-05-16 1978-01-17 Boehringer Ingelheim Gmbh N-(p-fluorobenzoyl-n-propyl)-4-piperidylamides and salts thereof
GB1498884A (en) * 1975-04-15 1978-01-25 Wyeth John & Brother Ltd Aminoacetamide-pyridyl-tetrahydropyridyl and-piperidyl derivatives
US4191683A (en) * 1975-05-28 1980-03-04 Ciba-Geigy Corporation Derivatives of 4-aminopiperidine as stabilizers for polymers
US4027028A (en) * 1975-11-10 1977-05-31 Science Union Et Cie Arylethers and pharmaceutical compositions
US4163789A (en) * 1976-02-17 1979-08-07 Anphar, S.A. Anti-psychotic (cycloalkenylalkylpiperidino) benzamides
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives
GB1582239A (en) * 1976-12-11 1981-01-07 Wyeth John & Brother Ltd Piperidin-4-yl ureas and thioureas
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
FR2530632A1 (fr) * 1982-07-26 1984-01-27 Bouchara Emile Nouveaux derives substitues du 2,5-diamino 1,4-diazole, leurs procedes de preparation et les compositions pharmaceutiques en renfermant
JPS6084281A (ja) * 1983-09-14 1985-05-13 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド類
JPS60123485A (ja) * 1983-12-08 1985-07-02 Yoshitomi Pharmaceut Ind Ltd インド−ル−３−カルボキサミド誘導体
JPS60142981A (ja) * 1983-12-28 1985-07-29 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド誘導体
US4569933A (en) * 1984-04-13 1986-02-11 Cornu Pierre Jean Antihypertensive substituted derivatives of 2,5-diamino 1,4-diazole
JP2832979B2 (ja) * 1988-02-15 1998-12-09 武田薬品工業株式会社 不飽和カルボン酸アミド誘導体
US5280032A (en) * 1989-02-14 1994-01-18 Toyama Chemical Co., Ltd. 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same
US4992446A (en) * 1989-09-05 1991-02-12 G. D. Searle & Co. Tricyclic quinolizine amides
US5053413A (en) * 1989-09-05 1991-10-01 G. D. Searle & Co. N-benzylpiperidineisoindolinones
US5210090A (en) * 1989-09-05 1993-05-11 G. D. Searle & Co. Substituted N-benzylpiperidine amides and cardiac regulatory compositions thereof
US5098915A (en) * 1989-09-05 1992-03-24 G. D. Searle & Co. Substituted N-benzylpiperidine amides
US5070094A (en) * 1989-09-05 1991-12-03 G. D. Searle & Co. N-benzyltropaneamides
US5028616A (en) * 1989-09-05 1991-07-02 G. D. Searle & Co. N-benzylpiperidine amides
US5578611A (en) * 1992-11-13 1996-11-26 Synaptic Pharmaceutical Corporation Use of α-1C specific compounds to treat benign prostatic hyperplasia
US5403847A (en) * 1992-11-13 1995-04-04 Synaptic Pharmaceutical Corporation Use of α1C specific compounds to treat benign prostatic hyperlasia
US6015819A (en) * 1992-11-13 2000-01-18 Synaptic Pharmaceutical Corporation Use of alpha-1C specific compounds to treat benign prostatic hyperplasia
CZ130595A3 (en) * 1992-11-20 1995-10-18 Kaken Pharma Co Ltd Acetamide derivatives, medicaments based thereon and aminoethanethiol derivatives
IL154107A0 (en) 2000-07-26 2003-07-31 Smithkline Beecham Plc Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
FR2813306B1 (fr) * 2000-08-23 2005-10-21 Sanofi Synthelabo Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
KR20040090981A (ko) 2002-03-13 2004-10-27 얀센 파마슈티카 엔.브이. 신규한 히스톤 디아세틸라제 저해제로서의카보닐아미노-유도체
WO2003076438A1 (fr) 2002-03-13 2003-09-18 Janssen Pharmaceutica N.V. Derives piperazinyl-, piperidinyl- et morpholinyl- utilises en tant que nouveaux inhibiteurs d'histone deacetylase
CA2476296C (fr) 2002-03-13 2011-02-22 Janssen Pharmaceutica N.V. Derives amines en tant qu'inhibiteurs de l'histone desacetylase
OA12793A (en) 2002-03-13 2006-07-10 Janssen Pharmaceutica Nv Sulfonylamino-derivatives as novel inhibitors of histone deacetylase.
SG156687A1 (en) 2004-07-28 2009-11-26 Janssen Pharmaceutica Nv Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
CA2605272C (fr) 2005-05-18 2013-12-10 Janssen Pharmaceutica N.V. Derives substitues d'aminopropenyl-piperidine ou de morpholine utilises en tant qu'inhibiteurs de l'histone-desacetylase
WO2007082874A1 (fr) 2006-01-19 2007-07-26 Janssen Pharmaceutica N.V. Dérivés de pyridine et de pyrimidine en tant qu'inhibiteurs d'histone désacétylase
EP1981875B1 (fr) 2006-01-19 2014-04-16 Janssen Pharmaceutica N.V. Dérivés substitués d'indolyl-alkyl-amine en tant qu'inhibiteurs de l'histone désacétylase
US8101616B2 (en) 2006-01-19 2012-01-24 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
RS51191B (sr) 2006-01-19 2010-10-31 Janssen Pharmaceutica N.V. Derivati aminofenila kao novi inhibitori histon deacetilaze

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL267843A (fr) * 1960-08-03
US3270026A (en) * 1963-07-03 1966-08-30 Hoffmann La Roche Substituted benzamidotetrahydro-pyridines and processes
GB1154742A (en) * 1966-05-17 1969-06-11 Whitefin Holding Sa Pyrrylamino Ketones
GB1221061A (en) * 1967-01-18 1971-02-03 May & Baker Ltd Quaternary ammonium derivatives, their use as anthelmintics and methods for their preparation
US3855242A (en) * 1967-12-15 1974-12-17 Aspro Nicholas Ltd Benzo{8 b{9 thienyl-alkyl-guanidines
DE2060816C3 (de) * 1970-12-10 1980-09-04 Merck Patent Gmbh, 6100 Darmstadt 4-Phenylpiperidinderivate Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen enthaltend diese Verbindungen

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028365A (en) * 1970-09-03 1977-06-07 John Wyeth & Brother Limited Benz[g]indolyl compounds
US4675328A (en) * 1985-01-16 1987-06-23 Hoffmann-Laroche Inc. Phenyl-pyridinium salts and use thereof in inhibiting intestinal resorption
US4692450A (en) * 1985-01-16 1987-09-08 Hoffmann-La Roche Inc. Phenyl-pyrimidinium, thiazolium or imidazolium salts and use in inhibiting intestinal resorption of cholesterol and bile salts
US7205408B2 (en) 2001-01-22 2007-04-17 Smithkline Beecham, P.L.C. Quinolines and nitrogenated derivative thereof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents
US7109213B2 (en) 2002-01-29 2006-09-19 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US7312212B2 (en) 2002-01-29 2007-12-25 Glaxo Group Limited Aminopiperidine derivatives

Also Published As

Publication number Publication date
FR2105223A1 (fr) 1972-04-28
GB1345872A (en) 1974-02-06
AT316553B (de) 1974-07-25
NL7112176A (fr) 1972-03-07
AU3300571A (en) 1973-03-08
CH593258A5 (fr) 1977-11-30
US3907810A (en) 1975-09-23
CH598219A5 (fr) 1978-04-28
SE402284B (sv) 1978-06-26
CA955252A (en) 1974-09-24
US3910932A (en) 1975-10-07
CH598218A5 (fr) 1978-04-28
NL173954C (nl) 1984-04-02
US3917614A (en) 1975-11-04
DE2144080C2 (de) 1983-12-08
FR2105223B1 (fr) 1975-10-10
NL173954B (nl) 1983-11-01
AU461209B2 (en) 1975-05-22
AT319239B (de) 1974-12-10
US3912741A (en) 1975-10-14
DE2144080A1 (de) 1972-03-09

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: JOHN WYETH & BROTHER LTD

Effective date: 19910903