GB1450939A - - Google Patents
Info
- Publication number
- GB1450939A GB1450939A GB5881873A GB5881873A GB1450939A GB 1450939 A GB1450939 A GB 1450939A GB 5881873 A GB5881873 A GB 5881873A GB 5881873 A GB5881873 A GB 5881873A GB 1450939 A GB1450939 A GB 1450939A
- Authority
- GB
- United Kingdom
- Prior art keywords
- bile
- impurities
- purified
- drying
- animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000000941 bile Anatomy 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 239000012535 impurity Substances 0.000 abstract 3
- 238000004108 freeze drying Methods 0.000 abstract 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 238000012733 comparative method Methods 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 238000002036 drum drying Methods 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000000049 pigment Substances 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA180,969A CA1018153A (en) | 1972-09-21 | 1973-09-13 | Isolation of bile acids from natural sources |
| US417170A US3919266A (en) | 1972-09-21 | 1973-11-19 | Production of bile acids |
| GB5881873A GB1450939A (enrdf_load_stackoverflow) | 1973-12-19 | 1973-12-19 | |
| DE2400004A DE2400004A1 (de) | 1973-12-19 | 1974-01-02 | Verfahren zur gewinnung von reinen gallensaeuren |
| FR7401320A FR2257577B1 (enrdf_load_stackoverflow) | 1973-11-19 | 1974-01-15 | |
| BE143056A BE813549A (fr) | 1972-09-21 | 1974-04-10 | Procedes de production d'acides biliaires pratiquement purs |
| US05/547,854 US3931256A (en) | 1972-09-21 | 1975-02-06 | Chemical process for production of bile acids |
| CA225,959A CA1032530A (en) | 1973-12-19 | 1975-04-30 | PURIFICATION OF 3.alpha.,7.alpha.-DIHYDROXY-5-.beta.-CHOLANIC ACID |
| NL7505386A NL7505386A (nl) | 1973-12-19 | 1975-05-07 | Werkwijze voor de bereiding van galzuren. |
| GB14525/77A GB1489840A (en) | 1973-12-19 | 1975-05-07 | Inclusion complexes of 3alpha,7alpha-dihydroxy-5beta-cholanic acid |
| GB19262/75A GB1489839A (en) | 1973-12-19 | 1975-05-07 | Purification of 3alpha,7alpha-dihydroxy-5beta-cholanic acid |
| DE19752520488 DE2520488A1 (de) | 1973-12-19 | 1975-05-07 | Verfahren zur gewinnung reiner 3alpha,7alpha-dihydroxy-5beta-cholansaeure |
| FR7514427A FR2269957A1 (enrdf_load_stackoverflow) | 1973-12-19 | 1975-05-07 | |
| JP50055296A JPS5129211A (en) | 1973-12-19 | 1975-05-07 | 3 arufuaa 7 arufuaa jihidorokishi 5 beetaa koransannoseiho |
| US05/660,037 US4014908A (en) | 1972-09-21 | 1976-02-02 | Chemical process |
| US05/725,086 US4072695A (en) | 1972-09-21 | 1976-09-17 | 3α,7α-Dihydroxy-cholanic acid derivatives |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5881873A GB1450939A (enrdf_load_stackoverflow) | 1973-12-19 | 1973-12-19 | |
| DE2400004A DE2400004A1 (de) | 1973-12-19 | 1974-01-02 | Verfahren zur gewinnung von reinen gallensaeuren |
| FR7401320A FR2257577B1 (enrdf_load_stackoverflow) | 1973-11-19 | 1974-01-15 | |
| US46771074A | 1974-05-07 | 1974-05-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1450939A true GB1450939A (enrdf_load_stackoverflow) | 1976-09-29 |
Family
ID=34528009
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5881873A Expired GB1450939A (enrdf_load_stackoverflow) | 1972-09-21 | 1973-12-19 | |
| GB14525/77A Expired GB1489840A (en) | 1973-12-19 | 1975-05-07 | Inclusion complexes of 3alpha,7alpha-dihydroxy-5beta-cholanic acid |
| GB19262/75A Expired GB1489839A (en) | 1973-12-19 | 1975-05-07 | Purification of 3alpha,7alpha-dihydroxy-5beta-cholanic acid |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB14525/77A Expired GB1489840A (en) | 1973-12-19 | 1975-05-07 | Inclusion complexes of 3alpha,7alpha-dihydroxy-5beta-cholanic acid |
| GB19262/75A Expired GB1489839A (en) | 1973-12-19 | 1975-05-07 | Purification of 3alpha,7alpha-dihydroxy-5beta-cholanic acid |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5129211A (enrdf_load_stackoverflow) |
| CA (1) | CA1032530A (enrdf_load_stackoverflow) |
| DE (2) | DE2400004A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2269957A1 (enrdf_load_stackoverflow) |
| GB (3) | GB1450939A (enrdf_load_stackoverflow) |
| NL (1) | NL7505386A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112813128A (zh) * | 2021-01-12 | 2021-05-18 | 中山百灵生物技术股份有限公司 | 一种别熊去氧胆酸的合成方法 |
| CN113234115A (zh) * | 2021-05-31 | 2021-08-10 | 山东海钰生物技术股份有限公司 | 一种鸡胆汁中提取鹅去氧胆酸的生产工艺 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100658511B1 (ko) * | 2005-12-12 | 2006-12-19 | 주식회사 대웅제약 | 케노데옥시콜린산의 정제 방법 |
| KR100658512B1 (ko) * | 2005-12-30 | 2006-12-19 | 주식회사 대웅제약 | 케노데옥시콜린산의 정제 방법 |
-
1973
- 1973-12-19 GB GB5881873A patent/GB1450939A/en not_active Expired
-
1974
- 1974-01-02 DE DE2400004A patent/DE2400004A1/de active Pending
-
1975
- 1975-04-30 CA CA225,959A patent/CA1032530A/en not_active Expired
- 1975-05-07 FR FR7514427A patent/FR2269957A1/fr not_active Withdrawn
- 1975-05-07 JP JP50055296A patent/JPS5129211A/ja active Pending
- 1975-05-07 DE DE19752520488 patent/DE2520488A1/de not_active Withdrawn
- 1975-05-07 NL NL7505386A patent/NL7505386A/xx unknown
- 1975-05-07 GB GB14525/77A patent/GB1489840A/en not_active Expired
- 1975-05-07 GB GB19262/75A patent/GB1489839A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112813128A (zh) * | 2021-01-12 | 2021-05-18 | 中山百灵生物技术股份有限公司 | 一种别熊去氧胆酸的合成方法 |
| CN113234115A (zh) * | 2021-05-31 | 2021-08-10 | 山东海钰生物技术股份有限公司 | 一种鸡胆汁中提取鹅去氧胆酸的生产工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2520488A1 (de) | 1975-11-20 |
| CA1032530A (en) | 1978-06-06 |
| JPS5129211A (en) | 1976-03-12 |
| GB1489839A (en) | 1977-10-26 |
| FR2269957A1 (enrdf_load_stackoverflow) | 1975-12-05 |
| GB1489840A (en) | 1977-10-26 |
| DE2400004A1 (de) | 1975-07-03 |
| NL7505386A (nl) | 1975-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |