GB1432563A - Platinum- co-ordination compounds - Google Patents

Platinum- co-ordination compounds

Info

Publication number
GB1432563A
GB1432563A GB1645172A GB1645172A GB1432563A GB 1432563 A GB1432563 A GB 1432563A GB 1645172 A GB1645172 A GB 1645172A GB 1645172 A GB1645172 A GB 1645172A GB 1432563 A GB1432563 A GB 1432563A
Authority
GB
United Kingdom
Prior art keywords
phenylenediamine
april
halogen
optionally
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1645172A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rustenburg Platinum Mines Ltd
Original Assignee
Rustenburg Platinum Mines Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rustenburg Platinum Mines Ltd filed Critical Rustenburg Platinum Mines Ltd
Priority to GB1645172A priority Critical patent/GB1432563A/en
Priority to NL7304881A priority patent/NL7304881A/xx
Priority to FR7312663A priority patent/FR2182942B1/fr
Priority to US349187A priority patent/US3904663A/en
Priority to DE2318021A priority patent/DE2318021A1/de
Priority to JP4078073A priority patent/JPS535369B2/ja
Priority to SE7305077A priority patent/SE396755B/xx
Publication of GB1432563A publication Critical patent/GB1432563A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB1645172A 1972-04-10 1972-04-10 Platinum- co-ordination compounds Expired GB1432563A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
GB1645172A GB1432563A (en) 1972-04-10 1972-04-10 Platinum- co-ordination compounds
NL7304881A NL7304881A (https=) 1972-04-10 1973-04-09
FR7312663A FR2182942B1 (https=) 1972-04-10 1973-04-09
US349187A US3904663A (en) 1972-04-10 1973-04-09 Compositions containing platinum
DE2318021A DE2318021A1 (de) 1972-04-10 1973-04-10 Neue krebsmittel
JP4078073A JPS535369B2 (https=) 1972-04-10 1973-04-10
SE7305077A SE396755B (sv) 1972-04-10 1973-04-10 Sett att bereda en platinaforening med koordinerad bindning

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1645172A GB1432563A (en) 1972-04-10 1972-04-10 Platinum- co-ordination compounds
GB2139072 1972-05-08

Publications (1)

Publication Number Publication Date
GB1432563A true GB1432563A (en) 1976-04-22

Family

ID=26252050

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1645172A Expired GB1432563A (en) 1972-04-10 1972-04-10 Platinum- co-ordination compounds

Country Status (7)

Country Link
US (1) US3904663A (https=)
JP (1) JPS535369B2 (https=)
DE (1) DE2318021A1 (https=)
FR (1) FR2182942B1 (https=)
GB (1) GB1432563A (https=)
NL (1) NL7304881A (https=)
SE (1) SE396755B (https=)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4419340A (en) * 1969-03-24 1983-12-06 University Of Delaware Controlled release of anticancer agents from biodegradable polymers
GB1578323A (en) * 1976-02-26 1980-11-05 Rustenburg Platinum Mines Ltd Compositions containing platinum
GB1585103A (en) * 1976-04-06 1981-02-25 Rustenburg Platinum Mines Ltd Pharmaceutical compositions containing platinum compounds
US4255417A (en) * 1976-08-04 1981-03-10 Johnson Matthey, Inc. Platinum compounds for the irradication of skin blemishes
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4278660A (en) * 1977-05-02 1981-07-14 Research Corporation Complex or salt of a platinum (II) compound and a nitrogen containing polymer
US4151185A (en) * 1977-05-02 1979-04-24 Research Corporation Complex or salt of a platinum (II) compound and a nitrogen containing polymer
US4137248A (en) * 1977-08-29 1979-01-30 The United States Of America As Represented By The Department Of Health, Education And Welfare Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
SE447385B (sv) * 1977-10-19 1986-11-10 Johnson Matthey Co Ltd Cis-koordinationsforeningar av platina
US4203912A (en) * 1977-10-19 1980-05-20 Johnson, Matthey & Co., Limited Compositions containing platinum
SE447902B (sv) * 1977-10-19 1986-12-22 Johnson Matthey Co Ltd Cis-koordinationsforening av platina och komposition innehallande foreningen
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
US4405757A (en) * 1979-09-14 1983-09-20 Howell Bobby A Macromolecular complexes of amidocarbonylic water-soluble polymers and square planar platinous and equivalent organometallics
US4578491A (en) * 1982-06-28 1986-03-25 Engelhard Corporation Bis(thiocyanato)palladium(II) complexes
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
US4560782A (en) * 1982-11-19 1985-12-24 Research Corporation Anti-tumor diplatinum coordination compounds
US4533502A (en) * 1983-02-22 1985-08-06 Rochon Fernande D Platinum (II) compounds and their preparation
ATE52517T1 (de) * 1983-05-10 1990-05-15 Andrulis Res Corp Bis-platinkomplexe als antitumor-mittel.
US4544759A (en) * 1983-07-29 1985-10-01 American Cyanamid Company Platinum complexes of antitumor agents
US4588831A (en) * 1984-11-09 1986-05-13 Natec Platinum complex compounds of substituted 5,8-dihydroxyl-1,4-naphthoquinone, and process for their production and use
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5843475A (en) 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6588615B1 (en) * 1999-09-14 2003-07-08 Smithkline Beecham Corporation Container closure system having a cap removable with less than a 45° twist
AU1608801A (en) 1999-11-15 2001-05-30 Parker Hughes Institute Diamino platinum (ii) antitumor complexes
CA2535584A1 (en) * 2003-08-13 2005-02-24 University Of South Florida Platinum complexes for the treatment of tumors
US20050288365A1 (en) * 2004-01-06 2005-12-29 Heidi Kay Platinum complexes and methods for inhibiting tumor cell proliferation
US7977500B2 (en) * 2004-11-10 2011-07-12 University Of South Florida Platinum complexes for targeted drug delivery
WO2007006019A1 (en) * 2005-07-06 2007-01-11 University Of South Florida Materials and methods for screening, diagnosis and prognosis of conditions associated with stat protein expression
EP2345974B1 (en) 2006-06-28 2014-08-06 IHI Corporation Magnetically guidable compound
JP4774536B2 (ja) * 2006-11-06 2011-09-14 株式会社Ｉｈｉ 磁性材料、磁性材料の誘導装置及び磁性材料の設計方法
US20090169484A1 (en) 2007-12-28 2009-07-02 Ihi Corporation Iron-salen complex
JP5513405B2 (ja) 2008-11-20 2014-06-04 株式会社Ｉｈｉ 自己磁性金属サレン錯体化合物
DK3327148T3 (da) 2010-06-18 2021-04-12 Myriad Genetics Inc Fremgangsmåder til forudsigelse af status for brca1- og brca2-gener i en cancercelle
ES2704303T3 (es) 2010-08-24 2019-03-15 Dana Farber Cancer Inst Inc Procedimientos para la predicción de una respuesta contra el cáncer
EP4563709A3 (en) 2011-06-17 2025-09-03 Myriad Genetics, Inc. Methods and materials for assessing allelic imbalance
CN107267598B (zh) 2011-12-21 2022-03-25 美瑞德生物工程公司 用于评估杂合性丢失的方法与材料
WO2013130347A1 (en) 2012-02-23 2013-09-06 The Children's Hospital Corporation Methods for predicting anti-cancer response
ES2658867T3 (es) 2012-06-07 2018-03-12 Institut Curie Métodos para detectar la inactivación de la ruta de recombinación homóloga (BRCA1/2) en tumores humanos
WO2014160080A1 (en) 2013-03-14 2014-10-02 Children's Medical Center Corporation Cancer diagnosis, treatment selection and treatment
DK2981624T3 (da) 2013-04-05 2020-03-02 Myriad Genetics Inc Fremgangsmåder til vurdering af homolog rekombinationsdeficiens og forudsigelse af respons på cancerbehandling
EP3080292B1 (en) 2013-12-09 2022-02-02 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
EP4234711B1 (en) 2014-08-15 2025-05-28 Myriad Genetics, Inc. Methods and materials for assessing homologous recombination deficiency
EP4141127B1 (en) 2021-08-30 2024-10-09 Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln Method for assessing homologous recombination deficiency in ovarian cancer cells

Also Published As

Publication number Publication date
US3904663A (en) 1975-09-09
DE2318021A1 (de) 1973-11-08
SE396755B (sv) 1977-10-03
JPS535369B2 (https=) 1978-02-27
FR2182942B1 (https=) 1976-10-22
JPS4913317A (https=) 1974-02-05
NL7304881A (https=) 1973-10-12
FR2182942A1 (https=) 1973-12-14

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee