GB1422974A - Drying process - Google Patents
Drying processInfo
- Publication number
- GB1422974A GB1422974A GB1689073A GB1689073A GB1422974A GB 1422974 A GB1422974 A GB 1422974A GB 1689073 A GB1689073 A GB 1689073A GB 1689073 A GB1689073 A GB 1689073A GB 1422974 A GB1422974 A GB 1422974A
- Authority
- GB
- United Kingdom
- Prior art keywords
- spray
- bloom
- hydrolyzed gelatin
- silicic acid
- sodium benzoate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000001035 drying Methods 0.000 title abstract 2
- 108010010803 Gelatin Proteins 0.000 abstract 5
- 239000008273 gelatin Substances 0.000 abstract 5
- 229920000159 gelatin Polymers 0.000 abstract 5
- 235000019322 gelatine Nutrition 0.000 abstract 5
- 235000011852 gelatine desserts Nutrition 0.000 abstract 5
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 abstract 5
- 230000002745 absorbent Effects 0.000 abstract 4
- 239000002250 absorbent Substances 0.000 abstract 4
- 235000012239 silicon dioxide Nutrition 0.000 abstract 4
- 235000001809 DL-alpha-tocopherylacetate Nutrition 0.000 abstract 3
- 239000011626 DL-alpha-tocopherylacetate Substances 0.000 abstract 3
- ZAKOWWREFLAJOT-UHFFFAOYSA-N DL-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 abstract 3
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 3
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 abstract 3
- 235000010234 sodium benzoate Nutrition 0.000 abstract 3
- 239000004299 sodium benzoate Substances 0.000 abstract 3
- 235000010199 sorbic acid Nutrition 0.000 abstract 3
- 239000004334 sorbic acid Substances 0.000 abstract 3
- 229940075582 sorbic acid Drugs 0.000 abstract 3
- 239000007921 spray Substances 0.000 abstract 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 2
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 abstract 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- UAQIEOIQKQKBDW-UHFFFAOYSA-N 6-ethoxy-2,2,4-trimethyl-1H-quinoline-3,5-diol Chemical compound OC1=C2C(=C(C(NC2=CC=C1OCC)(C)C)O)C UAQIEOIQKQKBDW-UHFFFAOYSA-N 0.000 abstract 1
- 239000005995 Aluminium silicate Substances 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 abstract 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 abstract 1
- VYGQUTWHTHXGQB-UHFFFAOYSA-N Retinol hexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-UHFFFAOYSA-N 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- 229930003427 Vitamin E Natural products 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 229910052910 alkali metal silicate Inorganic materials 0.000 abstract 1
- 235000012211 aluminium silicate Nutrition 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 239000000378 calcium silicate Substances 0.000 abstract 1
- 229910052918 calcium silicate Inorganic materials 0.000 abstract 1
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 abstract 1
- 235000013339 cereals Nutrition 0.000 abstract 1
- 239000004927 clay Substances 0.000 abstract 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 abstract 1
- 229940038472 dicalcium phosphate Drugs 0.000 abstract 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 abstract 1
- 238000007907 direct compression Methods 0.000 abstract 1
- 239000010419 fine particle Substances 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000019634 flavors Nutrition 0.000 abstract 1
- 235000013312 flour Nutrition 0.000 abstract 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 1
- 239000011256 inorganic filler Substances 0.000 abstract 1
- 229910003475 inorganic filler Inorganic materials 0.000 abstract 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 abstract 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 abstract 1
- 239000001095 magnesium carbonate Substances 0.000 abstract 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940098458 powder spray Drugs 0.000 abstract 1
- 229940108325 retinyl palmitate Drugs 0.000 abstract 1
- 235000019172 retinyl palmitate Nutrition 0.000 abstract 1
- 239000011769 retinyl palmitate Substances 0.000 abstract 1
- 229960002477 riboflavin Drugs 0.000 abstract 1
- 235000019192 riboflavin Nutrition 0.000 abstract 1
- 239000002151 riboflavin Substances 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
- 235000019165 vitamin E Nutrition 0.000 abstract 1
- 239000011709 vitamin E Substances 0.000 abstract 1
- 229940046009 vitamin E Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/148—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A61K9/5057—Gelatin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/16—Evaporating by spraying
- B01D1/18—Evaporating by spraying to obtain dry solids
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24278972A | 1972-04-10 | 1972-04-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1422974A true GB1422974A (en) | 1976-01-28 |
Family
ID=22916188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1689073A Expired GB1422974A (en) | 1972-04-10 | 1973-04-09 | Drying process |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5418331B2 (enrdf_load_stackoverflow) |
AT (1) | AT353232B (enrdf_load_stackoverflow) |
BE (1) | BE797921A (enrdf_load_stackoverflow) |
CH (1) | CH586568A5 (enrdf_load_stackoverflow) |
DE (1) | DE2317434A1 (enrdf_load_stackoverflow) |
FR (1) | FR2179899B1 (enrdf_load_stackoverflow) |
GB (1) | GB1422974A (enrdf_load_stackoverflow) |
NL (1) | NL7304921A (enrdf_load_stackoverflow) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0088382A1 (en) * | 1982-03-09 | 1983-09-14 | Nippon Shinyaku Company, Limited | Stabilization of azulene derivatives |
WO2008130883A1 (en) * | 2007-04-16 | 2008-10-30 | Wyeth | Embedded liquid lubricants for tableting |
EP1811008A3 (en) * | 2006-01-18 | 2009-12-16 | Joseph Iannicelli | Method and composition for controlled heat release and disposable chemical heater utilizing same |
US9891239B2 (en) | 2007-02-23 | 2018-02-13 | Gilead Sciences, Inc. | Modulators of pharmacokinetic properties of therapeutics |
US10039718B2 (en) | 2008-05-02 | 2018-08-07 | Gilead Sciences, Inc. | Use of solid carrier particles to improve the processability of a pharmaceutical agent |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2546838B2 (ja) * | 1986-03-24 | 1996-10-23 | エフ・ホフマン―ラ ロシユ アーゲー | ビタミン製剤の製造方法 |
JP3555640B2 (ja) * | 1996-05-10 | 2004-08-18 | ライオン株式会社 | 天然カロチノイドを包含した多芯型構造のマイクロカプセル並びに錠剤、食品用及び医薬品用配合剤 |
AU5486899A (en) * | 1998-08-13 | 2000-03-06 | Cima Labs, Inc. | Microemulsions as solid dosage forms for oral administration |
JP2000086537A (ja) * | 1998-09-11 | 2000-03-28 | Fuji Chem Ind Co Ltd | 無機化合物糖類組成物、賦形剤、速崩壊性圧縮成型物及びその製造方法 |
EP1361866A4 (en) * | 2001-02-23 | 2007-10-17 | Cima Labs Inc | EMULSIONS AS SOLID DOSAGE FORMS FOR ORAL ADMINISTRATION |
WO2012089729A1 (en) * | 2010-12-27 | 2012-07-05 | Dsm Ip Assets B.V. | Improved powderous vitamin e formulations |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1266902A (fr) * | 1960-09-06 | 1961-07-17 | Procédé de production de préparations stables de vitamines | |
FR1546920A (fr) * | 1966-12-02 | 1968-11-22 | Niro Atomizer As | Roue d'atomisation simultanée de deux composants |
US3608083A (en) * | 1968-06-05 | 1971-09-21 | Hoffmann La Roche | Vitamin e powder |
-
1973
- 1973-04-03 CH CH473673A patent/CH586568A5/xx not_active IP Right Cessation
- 1973-04-06 JP JP3886373A patent/JPS5418331B2/ja not_active Expired
- 1973-04-06 DE DE19732317434 patent/DE2317434A1/de active Pending
- 1973-04-09 AT AT310873A patent/AT353232B/de not_active IP Right Cessation
- 1973-04-09 BE BE129771A patent/BE797921A/xx unknown
- 1973-04-09 NL NL7304921A patent/NL7304921A/xx not_active Application Discontinuation
- 1973-04-09 GB GB1689073A patent/GB1422974A/en not_active Expired
- 1973-04-10 FR FR7312823A patent/FR2179899B1/fr not_active Expired
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0088382A1 (en) * | 1982-03-09 | 1983-09-14 | Nippon Shinyaku Company, Limited | Stabilization of azulene derivatives |
EP1811008A3 (en) * | 2006-01-18 | 2009-12-16 | Joseph Iannicelli | Method and composition for controlled heat release and disposable chemical heater utilizing same |
US8080172B2 (en) | 2006-01-18 | 2011-12-20 | J.I. Enterprises, Inc. | Method and composition for controlled heat release and disposable chemical heater utilizing same |
US9891239B2 (en) | 2007-02-23 | 2018-02-13 | Gilead Sciences, Inc. | Modulators of pharmacokinetic properties of therapeutics |
WO2008130883A1 (en) * | 2007-04-16 | 2008-10-30 | Wyeth | Embedded liquid lubricants for tableting |
AU2008242256B2 (en) * | 2007-04-16 | 2011-11-03 | Pf Consumer Healthcare 1 Llc | Embedded liquid lubricants for tableting |
EP2599394A1 (en) * | 2007-04-16 | 2013-06-05 | Wyeth LLC | Embedded liquid lubricants for tableting |
US11013251B2 (en) | 2007-04-16 | 2021-05-25 | PF Consumer Healthcare 1, LLC | Embedded liquid lubricants for tableting |
US10039718B2 (en) | 2008-05-02 | 2018-08-07 | Gilead Sciences, Inc. | Use of solid carrier particles to improve the processability of a pharmaceutical agent |
Also Published As
Publication number | Publication date |
---|---|
NL7304921A (enrdf_load_stackoverflow) | 1973-10-12 |
JPS5418331B2 (enrdf_load_stackoverflow) | 1979-07-06 |
FR2179899A1 (enrdf_load_stackoverflow) | 1973-11-23 |
FR2179899B1 (enrdf_load_stackoverflow) | 1976-09-10 |
CH586568A5 (enrdf_load_stackoverflow) | 1977-04-15 |
AT353232B (de) | 1979-11-12 |
ATA310873A (de) | 1979-04-15 |
DE2317434A1 (de) | 1973-12-06 |
JPS497415A (enrdf_load_stackoverflow) | 1974-01-23 |
BE797921A (fr) | 1973-10-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1422974A (en) | Drying process | |
CA2176841A1 (en) | Feed additive | |
CA2260637A1 (en) | Free-flowable, directly compressible starch as binder, distinegrant and filler for compression tablets and hard gelatine capsules | |
IE791669L (en) | Preparation of gels | |
GB1310925A (en) | Methods of forming direct compression vehicles and tablets | |
US3875282A (en) | Production of high bulk density spray dried hydrous sodium silicate | |
GB1218222A (en) | Process for preparing a dry-shampoo in aerosol form | |
GB1493567A (en) | Process for preparation of granules containing viscous substances | |
GB1349409A (en) | Adsorbent material and method of preparing same | |
JPS5753403A (en) | Composition containing spray dry particle of n-acetyl-p-aminophenol and manufacture | |
ES471589A1 (es) | Procedimiento para la estabilizacion de percarbonato de so- dio | |
US2480103A (en) | Vitamin food product | |
GB1346152A (en) | Powder compositions | |
ES393211A1 (es) | Un procedimiento para la fabricacion de derivados de almi- don hidrofobos redispersables. | |
US2631977A (en) | Free flowing fire extinguishing compositions | |
CA1199871A (en) | Drug preparations for glycoside hydrolase inhibitors | |
GB1401295A (en) | Process for the production of hydrated mixed metal silicates | |
GB1397410A (en) | Yeast | |
JPH0566928B2 (enrdf_load_stackoverflow) | ||
IE801402L (en) | Gastric acid neutralizing agents | |
ES8100343A1 (es) | Un procedimiento para obtener un producto de tripolifosfato sodico granular | |
GB1476682A (en) | Bleaching formulation | |
IE42783L (en) | Aluminium polyhydroxysulphate | |
IE791670L (en) | Dehydrated edible product | |
GB1248054A (en) | Improvements in or relating to fire extinguishing compositions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |