GB1422280A - Aspirator for removal of the contents of cystic tumors - Google Patents

Aspirator for removal of the contents of cystic tumors

Info

Publication number
GB1422280A
GB1422280A GB5896873A GB5896873A GB1422280A GB 1422280 A GB1422280 A GB 1422280A GB 5896873 A GB5896873 A GB 5896873A GB 5896873 A GB5896873 A GB 5896873A GB 1422280 A GB1422280 A GB 1422280A
Authority
GB
United Kingdom
Prior art keywords
guide sleeve
suction
tube
aspirator
slots
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5896873A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1422280A publication Critical patent/GB1422280A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04R—LOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; DEAF-AID SETS; PUBLIC ADDRESS SYSTEMS
    • H04R5/00—Stereophonic arrangements
    • H04R5/02—Spatial or constructional arrangements of loudspeakers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Acoustics & Sound (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Signal Processing (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
GB5896873A 1972-12-27 1973-12-19 Aspirator for removal of the contents of cystic tumors Expired GB1422280A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP47130142A JPS5238680B2 (enExample) 1972-12-27 1972-12-27

Publications (1)

Publication Number Publication Date
GB1422280A true GB1422280A (en) 1976-01-21

Family

ID=15026959

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5896873A Expired GB1422280A (en) 1972-12-27 1973-12-19 Aspirator for removal of the contents of cystic tumors

Country Status (3)

Country Link
US (1) US3896810A (enExample)
JP (1) JPS5238680B2 (enExample)
GB (1) GB1422280A (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2481103A1 (fr) * 1980-04-23 1981-10-30 Enstroem Hans Bistouri medical pour recueillir une goutte de sang et son procede de fabrication
GB2216805A (en) * 1988-03-31 1989-10-18 Gary Gordon Murdoch Device for opening pimples

Families Citing this family (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351328A (en) * 1980-03-27 1982-09-28 Sontek Industries, Inc. Simultaneous respiration and endotracheal suctioning of a critically ill patient
USD271902S (en) 1981-02-26 1983-12-20 Campton Charles H Embalming trocar sterilizer
JPS57153878A (en) * 1981-03-18 1982-09-22 Hitachi Ltd Discharger for paper sheet
US4511356A (en) * 1983-02-22 1985-04-16 Edward C. Froning Cannula, obturator, stylet and needle hub connectors for lumbar disc puncture
US4577514A (en) * 1984-04-09 1986-03-25 Vanderbilt University Method and apparatus for sampling liquid phase components from a liquid-semisolid fluid
US4633865A (en) * 1984-07-19 1987-01-06 Rewoplan Medizin-Technische Einrichtungsgesellschaft Mbh Device for performing examinations and interventions in the abdominal cavity of a patient
US4596566A (en) * 1984-10-26 1986-06-24 Kay Dennis M Ostomy appliance with suction securing chamber
US4807625A (en) * 1987-07-07 1989-02-28 Singleton Rosa R Membrane puncturing aspirator with drainage shield
US4769003A (en) * 1987-08-19 1988-09-06 Keith Stamler Wound irrigation splashback shield
GB8807466D0 (en) * 1988-03-29 1988-05-05 Bentley A F Colostomy irrigation equipment
US5458138A (en) * 1990-05-23 1995-10-17 Gajo; Alden H. Nasopharyngeal fluid suction device
US5100387A (en) * 1990-07-02 1992-03-31 Ng Raymond C Disposable universal needle guide apparatus (for amniocentesis)
US5069665A (en) * 1990-07-02 1991-12-03 Ng Raymond C Fluid aspiration needle
US7198046B1 (en) * 1991-11-14 2007-04-03 Wake Forest University Health Sciences Wound treatment employing reduced pressure
US5645081A (en) * 1991-11-14 1997-07-08 Wake Forest University Method of treating tissue damage and apparatus for same
US5636643A (en) * 1991-11-14 1997-06-10 Wake Forest University Wound treatment employing reduced pressure
US5387203A (en) * 1993-06-28 1995-02-07 Goodrich; Hubert J. Subcutaneous extractor
US5312364A (en) * 1993-08-06 1994-05-17 Pyng Intraosseous infusion device
US5409462A (en) * 1993-12-30 1995-04-25 Cordis Corporation Cyst puncture catheter assembly
US5496290A (en) * 1994-11-23 1996-03-05 Ackrad Laboratories, Inc. Wound irrigation splash shield
US6019749A (en) * 1998-04-01 2000-02-01 Squeezease, Llc Apparatus and method for removing material from skin pores
US6736797B1 (en) 1998-06-19 2004-05-18 Unomedical A/S Subcutaneous infusion set
FR2787336B1 (fr) * 1998-12-22 2001-06-08 Francis Navarro Dispositif de maintien d'au moins un drain ou analogue
US6971999B2 (en) * 2001-11-14 2005-12-06 Medical Instill Technologies, Inc. Intradermal delivery device and method
JP2005511251A (ja) * 2001-12-17 2005-04-28 コーニンクレッカ　フィリップス　エレクトロニクス　エヌ　ヴィ 少なくとも２つの吸込みノズルを備えたパーソナルケア装置
US20030225347A1 (en) * 2002-06-03 2003-12-04 Argenta Louis C. Directed tissue growth employing reduced pressure
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
US7520872B2 (en) 2002-09-13 2009-04-21 Neogen Technologies, Inc. Closed wound drainage system
US6979324B2 (en) 2002-09-13 2005-12-27 Neogen Technologies, Inc. Closed wound drainage system
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
GB0325126D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus with heat
GB0325129D0 (en) 2003-10-28 2003-12-03 Smith & Nephew Apparatus in situ
US7585290B2 (en) * 2004-01-20 2009-09-08 Ethicon Endo-Surgery, Inc. Medical device for providing access
US8100887B2 (en) * 2004-03-09 2012-01-24 Bluesky Medical Group Incorporated Enclosure-based reduced pressure treatment system
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US7708724B2 (en) * 2004-04-05 2010-05-04 Blue Sky Medical Group Incorporated Reduced pressure wound cupping treatment system
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8137382B2 (en) 2004-11-05 2012-03-20 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US8361113B2 (en) 2006-02-03 2013-01-29 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US7749250B2 (en) 2006-02-03 2010-07-06 Biomet Sports Medicine, Llc Soft tissue repair assembly and associated method
US9017381B2 (en) 2007-04-10 2015-04-28 Biomet Sports Medicine, Llc Adjustable knotless loops
US9801708B2 (en) 2004-11-05 2017-10-31 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8118836B2 (en) 2004-11-05 2012-02-21 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8088130B2 (en) 2006-02-03 2012-01-03 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US7909851B2 (en) 2006-02-03 2011-03-22 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US8128658B2 (en) 2004-11-05 2012-03-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to bone
US7658751B2 (en) 2006-09-29 2010-02-09 Biomet Sports Medicine, Llc Method for implanting soft tissue
US8303604B2 (en) 2004-11-05 2012-11-06 Biomet Sports Medicine, Llc Soft tissue repair device and method
US8298262B2 (en) 2006-02-03 2012-10-30 Biomet Sports Medicine, Llc Method for tissue fixation
US7905904B2 (en) 2006-02-03 2011-03-15 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
WO2006086826A1 (en) * 2005-01-19 2006-08-24 Colocare Holdings Pty Limited Colostomy pump system1
US7837673B2 (en) * 2005-08-08 2010-11-23 Innovative Therapies, Inc. Wound irrigation device
US7608066B2 (en) * 2005-08-08 2009-10-27 Innovative Therapies, Inc. Wound irrigation device pressure monitoring and control system
US7540860B2 (en) * 2006-01-23 2009-06-02 Keith Stamler Wound irrigation splashback shield
US8597327B2 (en) 2006-02-03 2013-12-03 Biomet Manufacturing, Llc Method and apparatus for sternal closure
US8562647B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for securing soft tissue to bone
US10517587B2 (en) 2006-02-03 2019-12-31 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8968364B2 (en) 2006-02-03 2015-03-03 Biomet Sports Medicine, Llc Method and apparatus for fixation of an ACL graft
US8562645B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8801783B2 (en) 2006-09-29 2014-08-12 Biomet Sports Medicine, Llc Prosthetic ligament system for knee joint
US9468433B2 (en) 2006-02-03 2016-10-18 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US11311287B2 (en) 2006-02-03 2022-04-26 Biomet Sports Medicine, Llc Method for tissue fixation
US9538998B2 (en) 2006-02-03 2017-01-10 Biomet Sports Medicine, Llc Method and apparatus for fracture fixation
US9149267B2 (en) 2006-02-03 2015-10-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US9078644B2 (en) 2006-09-29 2015-07-14 Biomet Sports Medicine, Llc Fracture fixation device
US11259792B2 (en) 2006-02-03 2022-03-01 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US8652171B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Method and apparatus for soft tissue fixation
US20070239182A1 (en) * 2006-04-03 2007-10-11 Boston Scientific Scimed, Inc. Thrombus removal device
US20090270789A1 (en) * 2006-04-14 2009-10-29 Maxymiv George W Suction dome for atraumatically grasping or manipulating tissue
US8500818B2 (en) 2006-09-29 2013-08-06 Biomet Manufacturing, Llc Knee prosthesis assembly with ligament link
US8672969B2 (en) 2006-09-29 2014-03-18 Biomet Sports Medicine, Llc Fracture fixation device
US11259794B2 (en) 2006-09-29 2022-03-01 Biomet Sports Medicine, Llc Method for implanting soft tissue
US7931651B2 (en) * 2006-11-17 2011-04-26 Wake Lake University Health Sciences External fixation assembly and method of use
US8377016B2 (en) 2007-01-10 2013-02-19 Wake Forest University Health Sciences Apparatus and method for wound treatment employing periodic sub-atmospheric pressure
RU2333012C1 (ru) * 2007-03-12 2008-09-10 Виктор Петрович Ярошенко Устройство для аспирации жидкостного содержимого кистозных образований
US8083712B2 (en) 2007-03-20 2011-12-27 Neogen Technologies, Inc. Flat-hose assembly for wound drainage system
US8137354B2 (en) 2007-04-25 2012-03-20 Biomet Sports Medicine, Llc Localized cartilage defect therapy
US20120191181A1 (en) * 2007-04-27 2012-07-26 Kassab Ghassan S Systems and methods for localization of a puncture site relative to a mammalian tissue of interest
AU2008310819B2 (en) * 2007-10-10 2013-06-27 Wake Forest University Health Sciences Devices and methods for treating spinal cord tissue
WO2009067711A2 (en) 2007-11-21 2009-05-28 T.J. Smith & Nephew, Limited Suction device and dressing
JP5925990B2 (ja) * 2008-01-09 2016-05-25 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ 損傷した中枢神経系組織を処置するための装置
WO2009133943A1 (ja) 2008-04-30 2009-11-05 株式会社ジェノミックス 生体内機能的細胞の高効率採取法
US9289193B2 (en) * 2008-07-18 2016-03-22 Wake Forest University Health Sciences Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage
US12245759B2 (en) 2008-08-22 2025-03-11 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to bone
US12419632B2 (en) 2008-08-22 2025-09-23 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
JP2010075599A (ja) * 2008-09-29 2010-04-08 Create Medic Co Ltd 医療用器具
US20100298866A1 (en) * 2009-05-19 2010-11-25 Tyco Healthcare Group Lp Wound closure system and method of use
US12096928B2 (en) 2009-05-29 2024-09-24 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US20110015589A1 (en) * 2009-07-14 2011-01-20 Pal Svedman Disposable therapeutic device
US20110015585A1 (en) * 2009-07-14 2011-01-20 Pal Svedman Method and device for providing intermittent negative pressure wound healing
US20110112490A1 (en) * 2009-07-14 2011-05-12 Vogel David C Releasably Sealable Wound Dressing for NPWT
US8444613B2 (en) * 2009-07-14 2013-05-21 Richard Vogel Pump leak monitor for negative pressure wound therapy
US20110015590A1 (en) * 2009-07-14 2011-01-20 Pal Svedman Disposable therapeutic device
US20110015619A1 (en) * 2009-07-16 2011-01-20 Pal Svedman Wound dressings for negative pressure therapy in deep wounds and method of using
US20110112574A1 (en) * 2009-09-11 2011-05-12 Svedman Pal Paul Device for manual traction wound closure
CN102711777B (zh) 2009-10-28 2015-04-15 吉诺米克斯股份有限公司 利用骨髓间充质干细胞和/或多能干细胞的血中动员的组织再生促进剂
US8066243B2 (en) * 2010-01-08 2011-11-29 Richard C. Vogel Adapter for portable negative pressure wound therapy device
EP2539013B1 (en) * 2010-02-23 2018-04-04 L-Vad Technology Inc. Vacuum assisted percutaneous appliance
FR2962639B1 (fr) * 2010-07-13 2013-03-29 Univ Joseph Fourier Dispositif pour le controle d'un ecoulement sanguin se produisant dans une zone hemorragique
EP2632516A1 (en) * 2010-10-25 2013-09-04 Sanofi-Aventis Deutschland GmbH Device for controlling a penetration depth of injection needle
DK2703487T3 (en) 2011-04-26 2018-09-10 Genomix Co Ltd TIME TO INDUCTION Tissue Regeneration and its Use
US12329373B2 (en) 2011-05-02 2025-06-17 Biomet Sports Medicine, Llc Method and apparatus for soft tissue fixation
US9357991B2 (en) 2011-11-03 2016-06-07 Biomet Sports Medicine, Llc Method and apparatus for stitching tendons
US9357992B2 (en) 2011-11-10 2016-06-07 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
US9381013B2 (en) 2011-11-10 2016-07-05 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
EP2913059B1 (en) 2012-10-25 2018-04-11 Genomix Co., Ltd. Novel method for treating spinal cord injury using hmgb1 fragment
RU2647467C2 (ru) 2012-10-25 2018-03-15 Дженомикс Ко., Лтд. Новый способ лечения инфаркта миокарда с применением фрагмента hmgb1
US9757119B2 (en) 2013-03-08 2017-09-12 Biomet Sports Medicine, Llc Visual aid for identifying suture limbs arthroscopically
US10058344B2 (en) 2013-03-12 2018-08-28 Boston Scientific Scimed, Inc. Apparatus for tissue dissection with suction ring
US9918827B2 (en) 2013-03-14 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
EP2874546B1 (en) * 2013-10-07 2016-09-07 Regentis Biomaterials Ltd. Apparatus for treatment of cavities in a human body
US9872705B2 (en) * 2013-10-07 2018-01-23 Regentis Biomaterials Ltd. Treatment of cavities in a human body
US11007082B2 (en) 2014-07-23 2021-05-18 Innovative Therapies Inc. Foam laminate dressing
USD819809S1 (en) * 2016-11-01 2018-06-05 Q-Core Medical Ltd. Medical syringe extension device
USD819808S1 (en) * 2016-11-01 2018-06-05 Q-Core Medical Ltd. Medical syringe extension device
BR112019014921A2 (pt) 2017-01-27 2020-03-31 StemRIM Inc. Agente terapêutico para miocardiopatia, infarto antigo do miocárdio e insuficiência cardíaca crônica
CN107854736A (zh) * 2017-11-28 2018-03-30 刘玲 一种肿瘤内科临床用防渗透引流管
EP3719117A4 (en) 2017-12-01 2021-11-03 Stemrim Inc. EECTODERMAL MESENCHYMAL STEM CELLS AND METHOD FOR PRODUCING THEM
US11298403B2 (en) 2017-12-01 2022-04-12 StemRIM Inc. Therapeutic agent for inflammatory bowel disease
US20210024594A1 (en) 2018-02-08 2021-01-28 StemRIM Inc. Therapeutic Agent for Psoriasis
KR102613050B1 (ko) 2018-04-20 2023-12-15 삼성전자주식회사 이차전지용 복합막, 그 제조방법 및 이를 포함하는 이차전지
US12304933B2 (en) 2018-10-05 2025-05-20 StemRIM Inc. Disease treatment drug based on mesenchymal-stem-cell mobilization
CN113081072B (zh) * 2021-04-10 2023-02-28 范锋 一种基于中西医结合治疗肿瘤的肿瘤内科取样装置
KR102680455B1 (ko) * 2021-07-27 2024-07-02 포항공과대학교 산학협력단 리튬 이차전지 전해질 적용을 위한 비수계 프리스탠딩 이온 전도성 젤 및 그의 제조방법
CN114521975B (zh) * 2022-03-22 2023-05-30 袁中芹 一种肿瘤科用肿瘤吸附夹

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2945496A (en) * 1958-08-18 1960-07-19 Fosdal Alfred Dental instrument for immobilizing tissue
US3608540A (en) * 1969-02-24 1971-09-28 St Croix Research Co Method and apparatus for aiding in the detection of breast cancer
US3786801A (en) * 1969-02-24 1974-01-22 Diagnostic Inc Method and apparatus for aiding in the detection of breast cancer
GB1323675A (en) * 1969-07-09 1973-07-18 Nat Res Dev Endoscopes
US3605747A (en) * 1969-12-19 1971-09-20 Fredric J Pashkow Surgical drain
US3658066A (en) * 1970-03-09 1972-04-25 Farrokh Saidi Cryosurgical appliance

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2481103A1 (fr) * 1980-04-23 1981-10-30 Enstroem Hans Bistouri medical pour recueillir une goutte de sang et son procede de fabrication
GB2216805A (en) * 1988-03-31 1989-10-18 Gary Gordon Murdoch Device for opening pimples

Also Published As

Publication number Publication date
JPS5238680B2 (enExample) 1977-09-30
DE2364692B2 (de) 1977-05-12
JPS4987177A (enExample) 1974-08-21
US3896810A (en) 1975-07-29
DE2364692A1 (de) 1974-07-04

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee