GB1418399A - Antibiotic derivatives - Google Patents
Antibiotic derivativesInfo
- Publication number
- GB1418399A GB1418399A GB1129673A GB1129673A GB1418399A GB 1418399 A GB1418399 A GB 1418399A GB 1129673 A GB1129673 A GB 1129673A GB 1129673 A GB1129673 A GB 1129673A GB 1418399 A GB1418399 A GB 1418399A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- formula
- acylating
- tobramycin
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 8
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical class N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 229960000707 tobramycin Drugs 0.000 abstract 2
- -1 L - (-) - γ - amino - α - hydroxybutyryl Chemical group 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- VFNGKCDDZUSWLR-UHFFFAOYSA-N disulfuric acid Chemical compound OS(=O)(=O)OS(O)(=O)=O VFNGKCDDZUSWLR-UHFFFAOYSA-N 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23297872A | 1972-03-08 | 1972-03-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1418399A true GB1418399A (en) | 1975-12-17 |
Family
ID=22875369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1129673A Expired GB1418399A (en) | 1972-03-08 | 1973-03-08 | Antibiotic derivatives |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5133551B2 (enrdf_load_stackoverflow) |
| AR (1) | AR205516A1 (enrdf_load_stackoverflow) |
| BE (1) | BE796491A (enrdf_load_stackoverflow) |
| FR (1) | FR2181797B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1418399A (enrdf_load_stackoverflow) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE417972B (sv) * | 1973-02-23 | 1981-04-27 | Bristol Myers Co | Forfarande for framstellning av antibiotiska derivat av kanamycin a eller b |
| CA1105455A (en) * | 1977-09-19 | 1981-07-21 | Junji Irisawa | Aminoglycoside derivatives |
| JPS5461151A (en) * | 1977-10-25 | 1979-05-17 | Shionogi & Co Ltd | Novel aminoglycoside derivative |
| US4656160A (en) * | 1984-11-29 | 1987-04-07 | Fujisawa Pharmaceutical Co., Ltd. | Aminoglycoside derivatives |
| JP2716458B2 (ja) * | 1988-06-03 | 1998-02-18 | シチズン時計株式会社 | スベリ軸受のスキマ調整構造 |
| JPH02145054U (enrdf_load_stackoverflow) * | 1989-05-13 | 1990-12-10 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT288594B (de) * | 1968-03-25 | 1971-03-10 | Parke Davis & Co | Verfahren zur Herstellung neuer antibiotisch wirksamer Verbindungen |
-
1973
- 1973-01-01 AR AR24695973A patent/AR205516A1/es active
- 1973-03-07 FR FR7308174A patent/FR2181797B1/fr not_active Expired
- 1973-03-08 BE BE128558A patent/BE796491A/xx not_active IP Right Cessation
- 1973-03-08 GB GB1129673A patent/GB1418399A/en not_active Expired
- 1973-03-08 JP JP2663573A patent/JPS5133551B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2181797A1 (enrdf_load_stackoverflow) | 1973-12-07 |
| JPS5133551B2 (enrdf_load_stackoverflow) | 1976-09-20 |
| FR2181797B1 (enrdf_load_stackoverflow) | 1976-10-22 |
| BE796491A (fr) | 1973-09-10 |
| JPS4918850A (enrdf_load_stackoverflow) | 1974-02-19 |
| DE2311524B2 (de) | 1975-07-10 |
| DE2311524A1 (de) | 1973-09-20 |
| AR205516A1 (es) | 1976-05-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |