GB1380507A - Process for the preparation of 2,4-diaryl thiazoline and thiazole derivatives - Google Patents
Process for the preparation of 2,4-diaryl thiazoline and thiazole derivativesInfo
- Publication number
- GB1380507A GB1380507A GB3249872A GB3249872A GB1380507A GB 1380507 A GB1380507 A GB 1380507A GB 3249872 A GB3249872 A GB 3249872A GB 3249872 A GB3249872 A GB 3249872A GB 1380507 A GB1380507 A GB 1380507A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- prepared
- compound
- formula
- thiazoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000007979 thiazole derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- MEKOFIRRDATTAG-UHFFFAOYSA-N 2,2,5,8-tetramethyl-3,4-dihydrochromen-6-ol Chemical compound C1CC(C)(C)OC2=C1C(C)=C(O)C=C2C MEKOFIRRDATTAG-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 150000003557 thiazoles Chemical class 0.000 abstract 2
- JYWKEVKEKOTYEX-UHFFFAOYSA-N 2,6-dibromo-4-chloroiminocyclohexa-2,5-dien-1-one Chemical compound ClN=C1C=C(Br)C(=O)C(Br)=C1 JYWKEVKEKOTYEX-UHFFFAOYSA-N 0.000 abstract 1
- RRHNMHKZFWKJMQ-UHFFFAOYSA-N 2-[4-(4-chlorophenyl)-4-hydroxy-2-phenyl-5H-1,3-thiazol-5-yl]acetic acid Chemical compound ClC1=CC=C(C=C1)C1(N=C(SC1CC(=O)O)C1=CC=CC=C1)O RRHNMHKZFWKJMQ-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 238000007171 acid catalysis Methods 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- -1 salt nitrile Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7126472A FR2146575A5 (enrdf_load_stackoverflow) | 1971-07-20 | 1971-07-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1380507A true GB1380507A (en) | 1975-01-15 |
Family
ID=9080597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3249872A Expired GB1380507A (en) | 1971-07-20 | 1972-07-12 | Process for the preparation of 2,4-diaryl thiazoline and thiazole derivatives |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5026544B1 (enrdf_load_stackoverflow) |
| CH (1) | CH562816A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2234675A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2146575A5 (enrdf_load_stackoverflow) |
| GB (1) | GB1380507A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002083111A3 (en) * | 2001-04-16 | 2004-04-15 | Tanabe Seiyaku Co | Imidazole, thiazole and oxazole derivatives and their use for the manufacture of a medicament for the treatment and/or prevention of pollakiuria or urinary incontinence |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR74148B (enrdf_load_stackoverflow) * | 1980-04-03 | 1984-06-06 | Wyeth John & Brother Ltd | |
| JPS6187783U (enrdf_load_stackoverflow) * | 1984-11-16 | 1986-06-09 |
-
1971
- 1971-07-20 FR FR7126472A patent/FR2146575A5/fr not_active Expired
-
1972
- 1972-07-11 CH CH1037172A patent/CH562816A5/xx not_active IP Right Cessation
- 1972-07-12 GB GB3249872A patent/GB1380507A/en not_active Expired
- 1972-07-14 DE DE19722234675 patent/DE2234675A1/de active Pending
- 1972-07-18 JP JP7194572A patent/JPS5026544B1/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002083111A3 (en) * | 2001-04-16 | 2004-04-15 | Tanabe Seiyaku Co | Imidazole, thiazole and oxazole derivatives and their use for the manufacture of a medicament for the treatment and/or prevention of pollakiuria or urinary incontinence |
| US7759373B2 (en) | 2001-04-16 | 2010-07-20 | Mitsubishi Tanabe Pharma Corporation | Large conductance calcium-activated K channel opener |
Also Published As
| Publication number | Publication date |
|---|---|
| CH562816A5 (enrdf_load_stackoverflow) | 1975-06-13 |
| FR2146575A5 (enrdf_load_stackoverflow) | 1973-03-02 |
| DE2234675A1 (de) | 1973-02-01 |
| JPS5026544B1 (enrdf_load_stackoverflow) | 1975-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 414F | Notice of opposition given (sect. 14/1949) | ||
| 414B | Case decided by the comptroller ** grants allowed (sect. 14/1949) | ||
| 49R | Reference inserted (sect. 9/1949) | ||
| PS | Patent sealed | ||
| SP | Amendment (slips) printed | ||
| PCNP | Patent ceased through non-payment of renewal fee |