GB651165A - Improvements in or relating to the preparation of ª†-methyl-mercapto-ª‡-aminobutyricacid - Google Patents

Improvements in or relating to the preparation of ª†-methyl-mercapto-ª‡-aminobutyricacid

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Publication number
GB651165A
GB651165A GB18586/48A GB1858648A GB651165A GB 651165 A GB651165 A GB 651165A GB 18586/48 A GB18586/48 A GB 18586/48A GB 1858648 A GB1858648 A GB 1858648A GB 651165 A GB651165 A GB 651165A
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GB
United Kingdom
Prior art keywords
methionine
heated
acetic acid
product
acidified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB18586/48A
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Individual
Original Assignee
Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB651165A publication Critical patent/GB651165A/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Methionine is obtained by reacting a -amino butyrolactone with sodium methyl mercaptide at between 150 DEG and 200 DEG C. and recovering the free acid from the resulting sodium salt. The lactone may be added to a suspension of the sodium methyl mercaptide in an inert solvent and the product formed then heated at 150 DEG to 200 DEG C. Free methionine may be obtained from the sodium salt formed by dissolving the latter in water and acidifying, e.g. with acetic acid to a pH value of 7. In examples: (1) a mixture of the reactants is heated to 180 DEG C. in an oil bath and after cooling the product is dissolved in water and acidified to a pH of 7 with acetic acid to yield methionine; (2) a -amino butyro lactone is added to a suspension of the mercaptide in xylene at 40 DEG C. A hard product is formed and after filtering off the xylene the residue is heated at 185 DEG C. in an oil bath. The melt is then dissolved in aqueous methanol and acidified with acetic acid as in (1) to form methionine.
GB18586/48A 1947-07-15 1948-07-10 Improvements in or relating to the preparation of ª†-methyl-mercapto-ª‡-aminobutyricacid Expired GB651165A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH651165X 1947-07-15

Publications (1)

Publication Number Publication Date
GB651165A true GB651165A (en) 1951-03-14

Family

ID=4526118

Family Applications (1)

Application Number Title Priority Date Filing Date
GB18586/48A Expired GB651165A (en) 1947-07-15 1948-07-10 Improvements in or relating to the preparation of ª†-methyl-mercapto-ª‡-aminobutyricacid

Country Status (1)

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GB (1) GB651165A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0245231A1 (en) * 1986-05-08 1987-11-11 Monsanto Company Process for the preparation of alkylthioalkanoate salts
US5175310A (en) * 1990-03-16 1992-12-29 Elf Atochem North America, Inc. Process for producing alkylthio- and arylthio-substituted carboxylic acids and their thioesters
US7884240B2 (en) * 2006-01-28 2011-02-08 Evonik Degussa Gmbh Method for production of methionine from homoserine
FR2965561A1 (en) * 2010-10-05 2012-04-06 Adisseo France Sas PROCESS FOR PREPARING AMINO ACID FROM 2-AMINOBUTYROLACTONE

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0245231A1 (en) * 1986-05-08 1987-11-11 Monsanto Company Process for the preparation of alkylthioalkanoate salts
US4777289A (en) * 1986-05-08 1988-10-11 Monsanto Company Process for the preparation of alkylthioalkanoate salts
US5175310A (en) * 1990-03-16 1992-12-29 Elf Atochem North America, Inc. Process for producing alkylthio- and arylthio-substituted carboxylic acids and their thioesters
US7884240B2 (en) * 2006-01-28 2011-02-08 Evonik Degussa Gmbh Method for production of methionine from homoserine
FR2965561A1 (en) * 2010-10-05 2012-04-06 Adisseo France Sas PROCESS FOR PREPARING AMINO ACID FROM 2-AMINOBUTYROLACTONE
WO2012045967A1 (en) * 2010-10-05 2012-04-12 Adisseo France S.A.S. Method for preparing an amino acid from 2-aminobutyrolactone
CN103153943A (en) * 2010-10-05 2013-06-12 安迪苏法国联合股份有限公司 Method for preparing an amino acid from 2-aminobutyrolactone
US8853428B2 (en) 2010-10-05 2014-10-07 Adisseo France S.A.S. Method for preparing an amino acid from 2 aminobutyrolactone
RU2561602C2 (en) * 2010-10-05 2015-08-27 Адиссео Франс С.А.С. Method of producing amino acid from 2-aminobutyrolactone

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