GB1366098A - Antibacterial agents - Google Patents
Antibacterial agentsInfo
- Publication number
- GB1366098A GB1366098A GB4261371A GB4261371A GB1366098A GB 1366098 A GB1366098 A GB 1366098A GB 4261371 A GB4261371 A GB 4261371A GB 4261371 A GB4261371 A GB 4261371A GB 1366098 A GB1366098 A GB 1366098A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- salt
- compound
- group
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- -1 α - Amino - α - phenylacetamido Chemical group 0.000 abstract 4
- 230000000903 blocking effect Effects 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 229960000583 acetic acid Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 239000012362 glacial acetic acid Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7217370A | 1970-09-14 | 1970-09-14 | |
| US7217270A | 1970-09-14 | 1970-09-14 | |
| US9218870A | 1970-11-23 | 1970-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1366098A true GB1366098A (en) | 1974-09-11 |
Family
ID=27372031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4261371A Expired GB1366098A (en) | 1970-09-14 | 1971-09-13 | Antibacterial agents |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS523948B1 (enrdf_load_stackoverflow) |
| BE (1) | BE772592A (enrdf_load_stackoverflow) |
| CH (1) | CH564025A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2145928A1 (enrdf_load_stackoverflow) |
| DK (1) | DK138746B (enrdf_load_stackoverflow) |
| ES (1) | ES395083A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2106501B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1366098A (enrdf_load_stackoverflow) |
| NL (1) | NL7112483A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2404592C2 (de) * | 1973-01-31 | 1984-01-19 | Bristol-Myers Co., 10154 New York, N.Y. | In 3-Stellung thiolierte 7-Acyl-amidocephalosporansäurederivate, Verfahren zu deren Herstellung und sie enthaltende Mittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL140413B (nl) * | 1968-06-14 | 1973-12-17 | Glaxo Lab Ltd | Werkwijze voor de bereiding van cefalosporinederivaten bevattende farmaceutische preparaten. |
| ZA698494B (en) * | 1969-02-26 | 1971-07-28 | Lilly Co Eli | Sulfur-containing cephalosporing antibiotics |
-
1971
- 1971-09-10 NL NL7112483A patent/NL7112483A/xx not_active Application Discontinuation
- 1971-09-13 FR FR7132975A patent/FR2106501B1/fr not_active Expired
- 1971-09-13 GB GB4261371A patent/GB1366098A/en not_active Expired
- 1971-09-13 CH CH1339271A patent/CH564025A5/xx not_active IP Right Cessation
- 1971-09-14 DK DK448971A patent/DK138746B/da unknown
- 1971-09-14 BE BE772592A patent/BE772592A/xx unknown
- 1971-09-14 ES ES395083A patent/ES395083A1/es not_active Expired
- 1971-09-14 DE DE19712145928 patent/DE2145928A1/de active Pending
- 1971-09-14 JP JP46070983A patent/JPS523948B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2106501B1 (enrdf_load_stackoverflow) | 1975-08-01 |
| DE2145928A1 (de) | 1972-03-23 |
| ES395083A1 (es) | 1974-12-16 |
| FR2106501A1 (enrdf_load_stackoverflow) | 1972-05-05 |
| JPS523948B1 (enrdf_load_stackoverflow) | 1977-01-31 |
| DK138746C (enrdf_load_stackoverflow) | 1979-03-26 |
| DK138746B (da) | 1978-10-23 |
| CH564025A5 (enrdf_load_stackoverflow) | 1975-07-15 |
| NL7112483A (enrdf_load_stackoverflow) | 1972-03-16 |
| BE772592A (fr) | 1972-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602004012269T2 (de) | Quervernetzte glycopeptid-cephalosporin-antibiotika | |
| JPS5756485A (en) | Cephem of penam compound and its preparation | |
| GB1302002A (enrdf_load_stackoverflow) | ||
| US3741962A (en) | Alpha-thioureidocephalosporanic acid compounds | |
| GB1604822A (en) | N-monosubstituted-9-amino-9-deoxyclavulanic acid derivative | |
| JPS5540621A (en) | Novel aminoglycoside derivative | |
| GB1392536A (en) | Antibacterial agent and a process for the preparation thereof | |
| GB1366098A (en) | Antibacterial agents | |
| US3657232A (en) | 7-((o-aminomethylphenylthio)-acetamido) cephalosporanic acid | |
| JPS57203087A (en) | Production of antibacterial | |
| GB1392241A (en) | Antibacterial agents and a process for the preparation thereof | |
| IE810452L (en) | Orally administrable drug form | |
| DE2158123A1 (de) | Neue pharmazeutische Präparate | |
| DE2629926A1 (de) | Clavulansaeureamide, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate | |
| US3682981A (en) | 2-amino-2-(1,4-cyclohexadienyl) acetic acid | |
| GB1360860A (en) | Cepham compounds process for their manufacture and compositions containing them | |
| SE8008540L (sv) | N-substituerade tiazolylderivat av oxi-imino-substituerade cefalosporiner och forfarande for framstellning derav | |
| GB1334079A (en) | 7-alpha-2,6-dihalo-4-pyridylthio acetamido cephalosporanic acids and derivatives thereof | |
| US3476738A (en) | Pentakis(n-(sulfomethyl))circulin and salts thereof | |
| IE35016B1 (en) | Cephalosporanic acids | |
| DE2112058A1 (de) | Chemische Verbindungen und Verfahren zu ihrer Herstellung | |
| IL43609A (en) | Pharmaceutical mixtures contain salts of sulphoglycopeptides with amino acids | |
| AT310355B (de) | Verfahren zur Herstellung von neuen Aminopenicillinsäurederivaten | |
| AT331981B (de) | Verfahren zur herstellung neuer amidinopenicillansaureester | |
| ES451449A1 (es) | Un procedimiento para la preparacion de nuevos derivados delacido 6-(d-2-acilamido-2-fenilacetamido)penicilanico. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |