GB1457237A - Cephalosporin compounds - Google Patents
Cephalosporin compoundsInfo
- Publication number
- GB1457237A GB1457237A GB2181675A GB2181675A GB1457237A GB 1457237 A GB1457237 A GB 1457237A GB 2181675 A GB2181675 A GB 2181675A GB 2181675 A GB2181675 A GB 2181675A GB 1457237 A GB1457237 A GB 1457237A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- tert
- butyl
- converting
- monoester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
1457237 Cephem compounds RECHERCHE ET INDUSTRIE THERAPEUTIQUES 21 May 1975 [22 May 1974 2 Jan 1975] 21816/75 Heading C2C The invention comprises compounds of formula and their non-toxic pharmaceutically acceptable salts. In examples, these compounds are prepared by converting benzyl or tert-butyl thienylacetate to the corresponding malonate monoester, converting this to monobenzyl (or tert - butyl)mono(2,5 - dioxopyrrolidin - 1 - yl)- thienylmalonate, reacting the latter with the corresponding amino / methyltetrazolylthiomethyl cephen compound, and finally hydrolysing the thus-formed side-chain monoester of I. Thereapeutic compositions having antibacterial activity comprise compounds of the above formula and may be administered by injection.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47226374A | 1974-05-22 | 1974-05-22 | |
| US53798775A | 1975-01-02 | 1975-01-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1457237A true GB1457237A (en) | 1976-12-01 |
Family
ID=27043712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2181675A Expired GB1457237A (en) | 1974-05-22 | 1975-05-21 | Cephalosporin compounds |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS511489A (en) |
| AU (1) | AU8059475A (en) |
| CA (1) | CA1041087A (en) |
| DE (1) | DE2521062A1 (en) |
| DK (1) | DK203575A (en) |
| ES (1) | ES437182A1 (en) |
| FR (1) | FR2271827A1 (en) |
| GB (1) | GB1457237A (en) |
| IE (1) | IE41622B1 (en) |
| IL (1) | IL47176A0 (en) |
| LU (1) | LU72530A1 (en) |
| NL (1) | NL7505962A (en) |
| SE (1) | SE7504669L (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5321191A (en) * | 1976-08-10 | 1978-02-27 | Shionogi & Co Ltd | 7-arylmalonamidocephem derivatives |
| JPS60215690A (en) * | 1984-04-09 | 1985-10-29 | Meiji Seika Kaisha Ltd | Cephalosporin compound and antibacterial agent containing said compound as active component |
-
1975
- 1975-04-23 SE SE7504669A patent/SE7504669L/en unknown
- 1975-04-25 IL IL47176A patent/IL47176A0/en unknown
- 1975-04-28 AU AU80594/75A patent/AU8059475A/en not_active Expired
- 1975-04-29 FR FR7513352A patent/FR2271827A1/fr not_active Withdrawn
- 1975-04-29 ES ES437182A patent/ES437182A1/en not_active Expired
- 1975-05-07 DK DK203575A patent/DK203575A/en unknown
- 1975-05-12 DE DE19752521062 patent/DE2521062A1/en active Pending
- 1975-05-20 CA CA227,351A patent/CA1041087A/en not_active Expired
- 1975-05-20 LU LU72530A patent/LU72530A1/xx unknown
- 1975-05-21 GB GB2181675A patent/GB1457237A/en not_active Expired
- 1975-05-21 NL NL7505962A patent/NL7505962A/en unknown
- 1975-05-22 JP JP50061783A patent/JPS511489A/en active Pending
- 1975-05-22 IE IE1145/75A patent/IE41622B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES437182A1 (en) | 1977-01-16 |
| CA1041087A (en) | 1978-10-24 |
| IL47176A0 (en) | 1975-06-25 |
| NL7505962A (en) | 1975-11-25 |
| JPS511489A (en) | 1976-01-08 |
| FR2271827A1 (en) | 1975-12-19 |
| LU72530A1 (en) | 1975-10-08 |
| DK203575A (en) | 1975-11-23 |
| IE41622L (en) | 1975-11-22 |
| DE2521062A1 (en) | 1975-12-04 |
| IE41622B1 (en) | 1980-02-13 |
| SE7504669L (en) | 1975-11-24 |
| AU8059475A (en) | 1976-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 48R | Reference inserted (sect. 8/1949) | ||
| SP | Amendment (slips) printed | ||
| PCNP | Patent ceased through non-payment of renewal fee |